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Early detection of cancer plays a key role in improving survival rates, but identifying reliable biomarkers from RNA-seq data is still a major challenge. The data are high-dimensional, and conventional statistical methods often fail to…

Machine Learning · Computer Science 2025-12-09 Shreyas Shende , Varsha Narayanan , Vishal Fenn , Yiran Huang , Dincer Goksuluk , Gaurav Choudhary , Melih Agraz , Mengjia Xu

ECLAIRs is the next space borne instrument that will be fully dedicated to multi-wavelength studies of Gamma-Ray Bursts (GRBs). It consists of a coded mask telescope with a wide (~2 sr) field of view, made of 6400 CdTe pixels (~1000 cm^2),…

Astrophysics · Physics 2010-11-11 Diego Gotz

Blind source separation (BSS) aims at recovering signals from mixtures. This problem has been extensively studied in cases where the mixtures are contaminated with additive Gaussian noise. However, it is not well suited to describe data…

Machine Learning · Statistics 2018-12-12 I. El Hamzaoui , J. Bobin

The Green's function coupled cluster (GFCC) method is a powerful many-body tool for computing the electronic structure of molecular and periodic systems, especially when electrons of the system are strongly correlated. However, for the GFCC…

Computational Physics · Physics 2019-04-18 Bo Peng , Roel Van Beeumen , David B. Williams-Young , Karol Kowalski , Chao Yang

A programme is outlined for the assembly of a comprehensive dielectronic recombination database within the generalized collisional--radiative (GCR) framework. It is valid for modelling ions of elements in dynamic finite-density plasmas such…

Cancer is a complex disease characterized by uncontrolled cell growth and proliferation. T cell receptors (TCRs) are essential proteins for the adaptive immune system, and their specific recognition of antigens plays a crucial role in the…

Machine Learning · Computer Science 2023-09-07 Zahra Tayebi , Sarwan Ali , Prakash Chourasia , Taslim Murad , Murray Patterson

Multi-contrast super-resolution (MCSR) is crucial for enhancing MRI but current deep learning methods are limited. They typically require large, paired low- and high-resolution (LR/HR) training datasets, which are scarce, and are trained…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Yinzhe Wu , Hongyu Rui , Fanwen Wang , Jiahao Huang , Zhenxuan Zhang , Haosen Zhang , Zi Wang , Guang Yang

Cross-modal retrieval (CMR) is a fundamental task in multimedia research, focused on retrieving semantically relevant targets across different modalities. While traditional CMR methods match text and image via embedding-based similarity…

Information Retrieval · Computer Science 2025-04-18 Haoxuan Li , Yi Bin , Yunshan Ma , Guoqing Wang , Yang Yang , See-Kiong Ng , Tat-Seng Chua

Graphical modeling explores dependences among a collection of variables by inferring a graph that encodes pairwise conditional independences. For jointly Gaussian variables, this translates into detecting the support of the precision…

Methodology · Statistics 2018-02-16 Shota Katayama , Hironori Fujisawa , Mathias Drton

G protein-coupled receptors (GPCRs) govern diverse physiological processes and are central to modern pharmacology. Yet discovering GPCR modulators remains challenging because receptor activation often arises from complex allosteric effects…

Machine Learning · Computer Science 2026-02-03 Jingjie Ning , Xiangzhen Shen , Li Hou , Shiyi Shen , Jiahao Yang , Junrui Li , Hong Shan , Sanan Wu , Sihan Gao , H. Eric Xu , Xinheng He

Foreground removal remains an ongoing challenge in radio cosmology, and increasingly sensitive experiments necessitate more robust analysis techniques. In this work, we model simulated data from a single-dish intensity mapping experiment,…

Instrumentation and Methods for Astrophysics · Physics 2026-04-30 Geoff G. Murphy , Philip Bull , Mario G. Santos , Zheng Zhang , Steven Cunnington

We show that Gaussian process regression (GPR) allows representing multivariate functions with low-dimensional terms via kernel design. When using a kernel built with HDMR (High-dimensional model representation), one obtains a similar type…

Numerical Analysis · Mathematics 2023-01-27 Eita Sasaki , Manabu Ihara , Sergei Manzhos

Sparse phase retrieval aims to recover a $k$-sparse signal from $m$ phaseless measurements. While the theoretically optimal sample complexity for successful recovery is $\Omega(k \log n)$, existing algorithms can only achieve this bound for…

Information Theory · Computer Science 2026-03-30 Mengchu Xu , Yuxuan Zhang , Jian Wang

The analysis of high-dimensional data, common in fields such as genomics, is complicated by the presence of cellwise contamination, where individual cells rather than entire rows are corrupted. This contamination poses a significant…

Methodology · Statistics 2026-03-31 Anthony Christidis , Jeyshinee Pyneeandee , Gabriela Cohen-Freue

The study of the prompt high-energy emission of Gamma-Ray Bursts (GRBs) with SVOM relies on the observations performed by ECLAIRs (4-150 keV) and the Gamma-Ray Monitor (GRM, 0.015-5 MeV), the two wide field-of-view instruments on board the…

Many inspiraling and merging stellar remnants emit both gravitational and electromagnetic radiation as they orbit or collide. These gravitational wave events together with their associated electromagnetic counterparts provide insight about…

Instrumentation and Methods for Astrophysics · Physics 2021-03-17 Michael L. Katz , Olivia R. Cooper , Michael W. Coughlin , Kevin B. Burdge , Katelyn Breivik , Shane L. Larson

We describe the Microbial Community Reconstruction ({\bf MCR}) Problem, which is fundamental for microbiome analysis. In this problem, the goal is to reconstruct the identity and frequency of species comprising a microbial community, using…

Computational Engineering, Finance, and Science · Computer Science 2013-09-27 Or Zuk , Amnon Amir , Amit Zeisel , Ohad Shamir , Noam Shental

Sparse coding refers to the pursuit of the sparsest representation of a signal in a typically overcomplete dictionary. From a Bayesian perspective, sparse coding provides a Maximum a Posteriori (MAP) estimate of the unknown vector under a…

Signal Processing · Electrical Eng. & Systems 2019-09-04 Dror Simon , Jeremias Sulam , Yaniv Romano , Yue M. Lu , Michael Elad

Sparse linear system solvers ($Ax=b$) are critical computational kernels in Electronic Design Automation (EDA), underpinning vital simulations for modern IC and system design. Applications like power integrity verification and…

Numerical Analysis · Mathematics 2025-04-17 Nityanand Rai

The scanning electron microscope (SEM) produces an image of a sample by scanning it with a focused beam of electrons. The electrons interact with the atoms in the sample, which emit secondary electrons that contain information about the…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Shahar Tsiper , Or Dicker , Idan Kaizerman , Zeev Zohar , Mordechai Segev , Yonina C. Eldar