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Foundation models (FMs), large neural networks pretrained on extensive and diverse datasets, have revolutionized artificial intelligence and shown significant promise in medical imaging by enabling robust performance with limited labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Salah Ghamizi , Georgia Kanli , Yu Deng , Magali Perquin , Olivier Keunen

Clinical deployment of automated brain MRI analysis faces a fundamental challenge: clinical data is heterogeneous and noisy, and high-quality labels are prohibitively costly to obtain. Self-supervised learning (SSL) can address this by…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Asbjørn Munk , Stefano Cerri , Vardan Nersesjan , Christian Hedeager Krag , Jakob Ambsdorf , Pablo Rocamora García , Julia Machnio , Peirong Liu , Suhyun Ahn , Nasrin Akbari , Yasmina Al Khalil , Kimberly Amador , Sina Amirrajab , Tal Arbel , Meritxell Bach Cuadra , Ujjwal Baid , Bhakti Baheti , Jaume Banus , Kamil Barbierik , Christoph Brune , Yansong Bu , Baptiste Callard , Yuhan Chen , Cornelius Crijnen , Corentin Dancette , Peter Drotar , Prasad Dutande , Nils D. Forkert , Saurabh Garg , Jakub Gazda , Matej Gazda , Benoît Gérin , Partha Ghosh , Weikang Gong , Pedro M. Gordaliza , Sam Hashemi , Tobias Heimann , Fucang Jia , Jiexin Jiang , Emily Kaczmarek , Chris Kang , Seung Kwan Kang , Mohammad Khazaei , Julien Khlaut , Petros Koutsouvelis , Jae Sung Lee , Yuchong Li , Mengye Lyu , Mingchen Ma , Anant Madabhushi , Klaus H. Maier-Hein , Pierre Manceron , Andrés Martínez Mora , Moona Mazher , Felix Meister , Nataliia Molchanova , Steven A. Niederer , Leonard Nürnberg , Jinah Park , Abdul Qayyum , Jonas Richiardi , Antoine Saporta , Branislav Setlak , Ning Shen , Justin Szeto , Constantin Ulrich , Puru Vaish , Vibujithan Vigneshwaran , Leroy Volmer , Zihao Wang , Siqi Wei , Anthony Winder , Jelmer M. Wolterink , Maxence Wynen , Chang Yang , Si Young Yie , Mostafa Mehdipour Ghazi , Akshay Pai , Espen Jimenez Solem , Sebastian Nørgaard Llambias , Mikael Boesen , Michael Eriksen Benros , Juan Eugenio Iglesias , Mads Nielsen

Magnetic resonance imaging (MRI) data is heterogeneous due to differences in device manufacturers, scanning protocols, and inter-subject variability. A conventional way to mitigate MR image heterogeneity is to apply preprocessing…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Ekaterina Kondrateva , Polina Druzhinina , Alexandra Dalechina , Svetlana Zolotova , Andrey Golanov , Boris Shirokikh , Mikhail Belyaev , Anvar Kurmukov

Self-supervised fMRI foundation models have shown promising transfer performance, yet most rely on predefined region-level parcellations that discard fine-grained voxel information and introduce atlas-dependent biases. We propose Omni-fMRI,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-02 Mo Wang , Wenhao Ye , Junfeng Xia , Junxiang Zhang , Xuanye Pan , Minghao Xu , Haotian Deng , Hongkai Wen , Quanying Liu

Multi-sequence Magnetic Resonance Imaging (MRI) offers remarkable versatility, enabling the distinct visualization of different tissue types. Nevertheless, the inherent heterogeneity among MRI sequences poses significant challenges to the…

Current fMRI foundation models primarily rely on a limited range of brain states and mismatched pretraining tasks, restricting their ability to learn generalized representations across diverse brain states. We present \textit{Brain-DiT}, a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Junfeng Xia , Wenhao Ye , Xuanye Pan , Xinke Shen , Mo Wang , Quanying Liu

We present a foundation model for brain MRI that can work with different combinations of imaging sequences. The model uses one encoder with learnable modality embeddings, conditional layer normalization, and a masked autoencoding objective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Minh Sao Khue Luu , Bair N. Tuchinov

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Zhongying Deng , Cheng Tang , Ziyan Huang , Jiashi Lin , Ying Chen , Junzhi Ning , Chenglong Ma , Jiyao Liu , Wei Li , Yinghao Zhu , Shujian Gao , Yanyan Huang , Sibo Ju , Yanzhou Su , Pengcheng Chen , Wenhao Tang , Tianbin Li , Haoyu Wang , Yuanfeng Ji , Hui Sun , Shaobo Min , Liang Peng , Feilong Tang , Haochen Xue , Rulin Zhou , Chaoyang Zhang , Wenjie Li , Shaohao Rui , Weijie Ma , Xingyue Zhao , Yibin Wang , Kun Yuan , Zhaohui Lu , Shujun Wang , Jinjie Wei , Lihao Liu , Dingkang Yang , Lin Wang , Yulong Li , Haolin Yang , Yiqing Shen , Lequan Yu , Xiaowei Hu , Yun Gu , Yicheng Wu , Benyou Wang , Minghui Zhang , Angelica I. Aviles-Rivero , Qi Gao , Hongming Shan , Xiaoyu Ren , Fang Yan , Hongyu Zhou , Haodong Duan , Maosong Cao , Shanshan Wang , Bin Fu , Xiaomeng Li , Zhi Hou , Chunfeng Song , Lei Bai , Yuan Cheng , Yuandong Pu , Xiang Li , Wenhai Wang , Hao Chen , Jiaxin Zhuang , Songyang Zhang , Huiguang He , Mengzhang Li , Bohan Zhuang , Zhian Bai , Rongshan Yu , Liansheng Wang , Yukun Zhou , Xiaosong Wang , Xin Guo , Guanbin Li , Xiangru Lin , Dakai Jin , Mianxin Liu , Wenlong Zhang , Qi Qin , Conghui He , Yuqiang Li , Ye Luo , Nanqing Dong , Jie Xu , Wenqi Shao , Bo Zhang , Qiujuan Yan , Yihao Liu , Jun Ma , Zhi Lu , Yuewen Cao , Zongwei Zhou , Jianming Liang , Shixiang Tang , Qi Duan , Dongzhan Zhou , Chen Jiang , Yuyin Zhou , Yanwu Xu , Jiancheng Yang , Shaoting Zhang , Xiaohong Liu , Siqi Luo , Yi Xin , Chaoyu Liu , Haochen Wen , Xin Chen , Alejandro Lozano , Min Woo Sun , Yuhui Zhang , Yue Yao , Xiaoxiao Sun , Serena Yeung-Levy , Xia Li , Jing Ke , Chunhui Zhang , Zongyuan Ge , Ming Hu , Jin Ye , Zhifeng Li , Yirong Chen , Yu Qiao , Junjun He

Magnetic resonance imaging~(MRI) have played a crucial role in brain disease diagnosis, with which a range of computer-aided artificial intelligence methods have been proposed. However, the early explorations usually focus on the limited…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Jiayu Lei , Lisong Dai , Haoyun Jiang , Chaoyi Wu , Xiaoman Zhang , Yao Zhang , Jiangchao Yao , Weidi Xie , Yanyong Zhang , Yuehua Li , Ya Zhang , Yanfeng Wang

In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…

Computational Geometry · Computer Science 2025-09-11 Ty Easley , Kevin Freese , Elizabeth Munch , Janine Bijsterbosch

Purpose: This study provides the first comprehensive evaluation of foundation models in fetal ultrasound (US) imaging under low inter-class variability conditions. While recent vision foundation models such as DINOv3 have shown remarkable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Edoardo Conti , Riccardo Rosati , Lorenzo Federici , Adriano Mancini , Maria Chiara Fiorentin

Publicly available data is essential for the progress of medical image analysis, in particular for crafting machine learning models. Glioma is the most common group of primary brain tumors, and magnetic resonance imaging (MRI) is a widely…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Meryem Abbad Andaloussi , Raphael Maser , Frank Hertel , François Lamoline , Andreas Dominik Husch

Foundation models in artificial intelligence (AI) are transforming medical imaging by enabling general-purpose feature learning from large-scale, unlabeled datasets. In this work, we introduce BrainFound, a self-supervised foundation model…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Moona Mazher , Geoff J. M. Parker , Daniel C. Alexander

While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu

Foundation models are emerging as a powerful paradigm for fMRI analysis, but current approaches face a dual bottleneck of data- and training-efficiency. Atlas-based methods aggregate voxel signals into fixed regions of interest, reducing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Mo Wang , Junfeng Xia , Wenhao Ye , Enyu Liu , Kaining Peng , Jianfeng Feng , Quanying Liu , Hongkai Wen

We present FOMO260K, a large-scale, heterogeneous dataset of 260,927 brain Magnetic Resonance Imaging (MRI) scans from 77,589 MRI sessions and 55,378 subjects, aggregated from 910 publicly available sources. The dataset includes both…

We present Brain Harmony (BrainHarmonix), the first multimodal brain foundation model that unifies structural morphology and functional dynamics into compact 1D token representations. The model was pretrained on two of the largest…

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

3D structural Magnetic Resonance Imaging (MRI) brain scans are commonly acquired in clinical settings to monitor a wide range of neurological conditions, including neurodegenerative disorders and stroke. While deep learning models have…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

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