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With the potential of quantum algorithms to solve intractable classical problems, quantum computing is rapidly evolving and more algorithms are being developed and optimized. Expressing these quantum algorithms using a high-level language…

Quantum Physics · Physics 2020-05-28 N. Khammassi , I. Ashraf , J. v. Someren , R. Nane , A. M. Krol , M. A. Rol , L. Lao , K. Bertels , C. G. Almudever

Quantum computers are moving into HPC centers, and the main challenge is now integration rather than pure hardware access. Many current software paths still depend on vendor-specific adapter chains between user SDKs, schedulers, and backend…

This PhD thesis explores the potential of quantum computing to address computational challenges in high-energy physics (HEP). As the Standard Model (SM) leaves key questions unanswered and no signs of new physics have emerged since the…

Quantum Physics · Physics 2025-12-02 Jorge J. Martínez de Lejarza

We present a composable design scheme for the development of hybrid quantum/classical algorithms and workflows for applications of quantum simulation. Our object-oriented approach is based on constructing an expressive set of common data…

Quantum processors are now able to run quantum circuits that are infeasible to simulate classically, creating a need for benchmarks that assess a quantum processor's rate of errors when running these circuits. Here, we introduce a general…

Quantum Physics · Physics 2025-10-29 Jordan Hines , Timothy Proctor

Developing state-of-the-art classical simulators of quantum circuits is of utmost importance to test and evaluate early quantum technology and understand the true potential of full-blown error-corrected quantum computers. In the past few…

Quantum Physics · Physics 2022-01-03 Salvatore Mandrà , Jeffrey Marshall , Eleanor G. Rieffel , Rupak Biswas

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

We conducted a systematic survey of emerging quantum-HPC platforms, which integrate quantum computers and High-Performance Computing (HPC) systems through co-location. Currently, it remains unclear whether such platforms provide tangible…

Quantum computers are often treated as experimental add-ons that are loosely coupled to classical infrastructure through high-level interpreted languages and cloud-like orchestration. However, future deployments in both, high-performance…

Quantum Physics · Physics 2025-07-28 Ralf Ramsauer , Wolfgang Mauerer

Quantum computing is an emerging computational paradigm that leverages the laws of quantum mechanics to perform elementary logic operations. Existing programming models for quantum computing were designed with fault-tolerant hardware in…

Programming Languages · Computer Science 2019-09-06 Tiffany M. Mintz , Alexander J. Mccaskey , Eugene F. Dumitrescu , Shirley V. Moore , Sarah Powers , Pavel Lougovski

Quantum processing unit (QPU) has to satisfy highly demanding quantity and quality requirements on its qubits to produce accurate results for problems at useful scales. Furthermore, classical simulations of quantum circuits generally do not…

Emerging Technologies · Computer Science 2022-07-05 Wei Tang , Margaret Martonosi

Context: The emergence of quantum computing proposes a revolutionary paradigm that can radically transform numerous scientific and industrial application domains. The ability of quantum computers to scale computations beyond what the…

Quantum Physics · Physics 2024-08-07 Vlad Stirbu , Otso Kinanen , Majid Haghparast , Tommi Mikkonen

Quantum computing has the potential to offer substantial computational advantages over conventional computing. Recent advances in quantum computing hardware and algorithms have enabled a class of classically parallel quantum workloads,…

Quantum circuit execution is the central task in quantum computation. Due to inherent quantum-mechanical constraints, quantum computing workflows often involve a considerable number of independent measurements over a large set of slightly…

Quantum Physics · Physics 2024-06-06 Daniel Claudino , Dmitry I. Lyakh , Alexander J. McCaskey

A strategy for the orchestration of hybrid classical-quantum workloads on supercomputers featuring quantum devices is proposed. The method makes use of heterogeneous job launches with Slurm to interleave classical and quantum computation,…

Quantum Physics · Physics 2023-12-11 Aniello Esposito , Sebastien Cabaniols , Jessica R. Jones , David Brayford

This paper presents the definition and implementation of a quantum computer architecture to enable creating a new computational device - a quantum computer as an accelerator. In this paper, we present explicitly the idea of a quantum…

Quantum Physics · Physics 2020-10-20 K. Bertels , A. Sarkar , A. A. Mouedenne , T. Hubregtsen , A. Yadav , A. Krol , I. Ashraf

Recent advances in quantum computing have brought us closer to realizing the potential of this transformative technology. While significant strides have been made in quantum error correction, many challenges persist, particularly in the…

Quantum Physics · Physics 2025-12-03 Mateusz Meller , Vendel Szeremi , Oliver Thomson Brown

The challenge of scaling quantum computers to gain computational power is expected to lead to architectures with multiple connected quantum processing units (QPUs), commonly referred to as Distributed Quantum Computing (DQC). In parallel,…

We present ScaffCC, a scalable compilation and analysis framework based on LLVM, which can be used for compiling quantum computing applications at the logical level. Drawing upon mature compiler technologies, we discuss similarities and…