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Finding the ground state of spin glasses is a challenging problem with broad implications. Many hard optimization problems, including NP-complete problems, can be mapped, for instance, to the Ising spin glass model. We present a graph-based…

Disordered Systems and Neural Networks · Physics 2025-05-05 Seyed Ehsan Ghasempouri , Gerhard W. Dueck , Stijn De Baerdemacker

We present Quafu-Qcover, an open-source cloud-based software package designed for combinatorial optimization problems that support both quantum simulators and hardware backends. Quafu-Qcover provides a standardized and complete workflow for…

Quantum Physics · Physics 2023-05-30 BAQIS Quafu Group

Operation management of nuclear power plants consists of several computationally hard problems. Searching for an in-core fuel loading pattern is among them. The main challenge of this combinatorial optimization problem is the exponential…

Solving combinatorial optimization problems efficiently through emerging hardware by converting the problem to its equivalent Ising model and obtaining its ground state is known as Ising computing. Phase-binarized oscillators (PBO), modeled…

In quantum chemistry, self-consistent field (SCF) algorithms define a nonlinear optimization problem, with both continuous and discrete components. In this work, we derive Hartree-Fock-inspired SCF algorithms that can be exactly written as…

Quantum Physics · Physics 2025-06-05 Alexis Ralli , Tim Weaving , Peter V. Coveney , Peter J. Love

With the advent of quantum computers, many quantum computing algorithms are being developed. Solving linear systems is one of the most fundamental problems in almost all science and engineering. The Harrow-Hassidim-Lloyd algorithm, a…

Quantum Physics · Physics 2022-01-25 Kyungtaek Jun

Quantum Annealing (QA) can efficiently solve combinatorial optimization problems whose objective functions are represented by Quadratic Unconstrained Binary Optimization (QUBO) formulations. For broader applicability of QA, quadratization…

Quantum Physics · Physics 2025-07-29 Hyakka Nakada , Shu Tanaka

We propose an approach to solving constrained combinatorial optimization problems based on embedding the concept of Lagrangian duality into the framework of adiabatic quantum computation. Within the setting of circuit-model fault-tolerant…

Optimization and Control · Mathematics 2024-04-30 Einar Gabbassov , Gili Rosenberg , Artur Scherer

The Quantum Approximate Optimization Algorithm (QAOA) is a quantum algorithm that finds approximate solutions to problems in combinatorial optimization, especially those that can be formulated as a Quadratic Unconstrained Binary…

Quantum Physics · Physics 2025-09-23 Bikrant Bhattacharyya , Michael Capriotti , Reuben Tate

Heterogeneous HPC workflow scheduling under multiple hard constraints poses a challenging combinatorial optimization problem. Classical exact solvers guarantee optimality but face scalability limits, motivating interest in quantum-inspired…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-26 Aasish Kumar Sharma , Christian Boehme , Julian Kunkel

Quantum devices can be used to solve constrained combinatorial optimization (COPT) problems thanks to the use of penalization methods to embed the COPT problem's constraints in its objective to obtain a quadratic unconstrained binary…

Quantum Physics · Physics 2021-01-26 Rodolfo Quintero , David Bernal , Tamás Terlaky , Luis F. Zuluaga

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

Systems of correlated quantum matter can be a steep challenge to any would-be method of solution. Matrix-product state (MPS)-based methods can describe 1D systems quasiexactly, but often struggle to retain sufficient bipartite entanglement…

Strongly Correlated Electrons · Physics 2024-11-04 Gunnar Bollmark , Sam Mardazad , Johannes S. Hofmann , Adrian Kantian

We propose a hybrid quantum-classical algorithm for approximating the ground state of two-dimensional quantum systems using an isometric tensor network ansatz, which maps naturally to quantum circuits. Inspired by the density matrix…

Quantum computing holds the potential for quantum advantage in optimization problems, which requires advances in quantum algorithms and hardware specifications. Adiabatic quantum optimization is conceptually a valid solution that suffers…

Quadratic Unconstrained Binary Optimization (QUBO) is a general-purpose modeling framework for combinatorial optimization problems and is a requirement for quantum annealers. This paper utilizes the eigenvalue decomposition of the…

Optimization and Control · Mathematics 2021-06-22 Amit Verma , Mark Lewis

Finding the ground state of Ising spin glasses is notoriously difficult due to disorder and frustration. Often, this challenge is framed as a combinatorial optimization problem, for which a common strategy employs simulated annealing, a…

Recent years have seen significant advances in quantum/quantum-inspired technologies capable of approximately searching for the ground state of Ising spin Hamiltonians. The promise of leveraging such technologies to accelerate the solution…

Optimization and Control · Mathematics 2024-01-24 Robin Brown , David E. Bernal Neira , Davide Venturelli , Marco Pavone

Quantum Annealing (QA) and QAOA are promising quantum optimisation algorithms used for finding approximate solutions to combinatorial problems on near-term NISQ systems. Many NP-hard problems can be reformulated as Quadratic Unconstrained…

Quantum Physics · Physics 2025-10-06 Namasi G Sankar , Georgios Miliotis , Simon Caton

In this paper, we introduce three QUBO (Quadratic Unconstrained Binary Optimization) relaxations for the sparsest $k$-subgraph (SkS) problem: a quadratic penalty relaxation, a Lagrangian relaxation, and an augmented Lagrangian relaxation.…

Optimization and Control · Mathematics 2025-09-11 Omkar Bihani , Roman Kužel , Janez Povh , Dunja Pucher
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