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Covariate adjustment is a ubiquitous method used to estimate the average treatment effect (ATE) from observational data. Assuming a known graphical structure of the data generating model, recent results give graphical criteria for optimal…

Statistics Theory · Mathematics 2025-12-08 Alexander Mangulad Christgau , Anton Rask Lundborg , Niels Richard Hansen

Optimization techniques have been widely used in deformable registration, allowing for the incorporation of similarity metrics with regularization mechanisms. These regularization mechanisms are designed to mitigate the effects of trivial…

Computer Vision and Pattern Recognition · Computer Science 2014-04-10 Martin Rajchl , John S. H. Baxter , Wu Qiu , Ali R. Khan , Aaron Fenster , Terry M. Peters , Jing Yuan

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

Foundation models have recently achieved impressive success in computational pathology, demonstrating strong generalization across diverse histopathology tasks. However, existing models overlook the heterogeneous and non-uniform…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Di Zhang , Zhangpeng Gong , Xiaobo Pang , Jiashuai Liu , Junbo Lu , Hao Cui , Jiusong Ge , Zhi Zeng , Kai Yi , Yinghua Li , Si Liu , Tingsong Yu , Haoran Wang , Mireia Crispin-Ortuzar , Weimiao Yu , Chen Li , Zeyu Gao

In breast surgical planning, accurate registration of MR images across patient positions has the potential to improve the localisation of tumours during breast cancer treatment. While learning-based registration methods have recently become…

The conditional average treatment effect (CATE) is widely used in personalized medicine to inform therapeutic decisions. However, state-of-the-art methods for CATE estimation (so-called meta-learners) often perform poorly in the presence of…

Machine Learning · Computer Science 2026-03-12 Valentyn Melnychuk , Dennis Frauen , Jonas Schweisthal , Stefan Feuerriegel

This paper presents a predictive model for estimating regularization parameters of diffeomorphic image registration. We introduce a novel framework that automatically determines the parameters controlling the smoothness of diffeomorphic…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Jian Wang , Miaomiao Zhang

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Alessa Hering , Sarah de Boer , Anindo Saha , Jasper J. Twilt , Mattias P. Heinrich , Derya Yakar , Maarten de Rooij , Henkjan Huisman , Joeran S. Bosma

Deep learning has revolutionized image registration by its ability to handle diverse tasks while achieving significant speed advantages over conventional approaches. Current approaches, however, often employ globally uniform smoothness…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Xiang Chen , Fengting Zhang , Qinghao Liu , Min Liu , Kun Wu , Yaonan Wang , Hang Zhang

We consider the problem of uncertainty quantification in high dimensional regression and classification for which deep ensemble have proven to be promising methods. Recent observations have shown that deep ensemble often return…

Machine Learning · Computer Science 2023-04-11 Antoine de Mathelin , Francois Deheeger , Mathilde Mougeot , Nicolas Vayatis

Atlas construction is fundamental to medical image analysis, offering a standardized spatial reference for tasks such as population-level anatomical modeling. While data-driven registration methods have recently shown promise in pairwise…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Ziwei Zou , Bei Zou , Xiaoyan Kui , Wenqi Lu , Haoran Dou , Arezoo Zakeri , Timothy Cootes , Alejandro F Frangi , Jinming Duan

Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung

The nonrigid alignment between a pre-operative biomechanical model and an intra-operative observation is a critical step to track the motion of a soft organ in augmented surgery. While many elastic registration procedures introduce…

Optimization and Control · Mathematics 2022-06-23 Guillaume Mestdagh , Stéphane Cotin

Deformable registration consists of finding the best dense correspondence between two different images. Many algorithms have been published, but the clinical application was made difficult by the high calculation time needed to solve the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Théo Estienne , Maria Vakalopoulou , Enzo Battistella , Theophraste Henry , Marvin Lerousseau , Amaury Leroy , Nikos Paragios , Eric Deutsch

Classical pairwise image registration methods search for a spatial transformation that optimises a numerical measure that indicates how well a pair of moving and fixed images are aligned. Current learning-based registration methods have…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Yipeng Hu , Eli Gibson , Dean C. Barratt , Mark Emberton , J. Alison Noble , Tom Vercauteren

With the mass construction of Gen III nuclear reactors, it is a popular trend to use deep learning (DL) techniques for fast and effective diagnosis of possible accidents. To overcome the common problems of previous work in diagnosing…

Signal Processing · Electrical Eng. & Systems 2022-09-26 Chengyuan Li , Zhifang Qiu , Zhangrui Yan , Meifu Li

Deep learning methods typically depend on the availability of labeled data, which is expensive and time-consuming to obtain. Active learning addresses such effort by prioritizing which samples are best to annotate in order to maximize the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Sparse neural networks are a key factor in developing resource-efficient machine learning applications. We propose the novel and powerful sparse learning method Adaptive Regularized Training (ART) to compress dense into sparse networks.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Patrick Glandorf , Timo Kaiser , Bodo Rosenhahn

Image registration is an essential step in many medical image analysis tasks. Traditional methods for image registration are primarily optimization-driven, finding the optimal deformations that maximize the similarity between two images.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Shanlin Sun , Kun Han , Chenyu You , Hao Tang , Deying Kong , Junayed Naushad , Xiangyi Yan , Haoyu Ma , Pooya Khosravi , James S. Duncan , Xiaohui Xie