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Deformable registration is crucial in medical imaging. Several existing applications include lesion tracking, probabilistic atlas generation, and treatment response evaluation. However, current methods often lack robustness and…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Yunzheng Zhu , Aichi Chien , Kimaya kulkarni , Luoting Zhuang , Stephen Park , Ricky Savjani , Daniel Low , William Hsu

Network regularization is an effective tool for incorporating structural prior knowledge to learn coherent models over networks, and has yielded provably accurate estimates in applications ranging from spatial economics to neuroimaging…

Machine Learning · Computer Science 2020-06-02 Hongyuan You , Furkan Kocayusufoglu , Ambuj K. Singh

Medical image registration is critical for aligning anatomical structures across imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound. Among existing techniques, non-rigid registration (NRR)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Sneha Sree C. , Dattesh Shanbhag , Sudhanya Chatterjee

Recent advances in deep learning-based medical image registration have shown that training deep neural networks~(DNNs) does not necessarily require medical images. Previous work showed that DNNs trained on randomly generated images with…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Junyu Chen , Shuwen Wei , Yihao Liu , Aaron Carass , Yong Du

Deformation field estimation is an important and challenging issue in many medical image registration applications. In recent years, deep learning technique has become a promising approach for simplifying registration problems, and has been…

Computer Vision and Pattern Recognition · Computer Science 2020-04-17 Yujia Zhou , Shumao Pang , Jun Cheng , Yuhang Sun , Yi Wu , Lei Zhao , Yaqin Liu , Zhentai Lu , Wei Yang , Qianjin Feng

We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

Clinical decision making from magnetic resonance imaging (MRI) combines complementary information from multiple MRI sequences (defined as 'modalities'). MRI image registration aims to geometrically 'pair' diagnoses from different…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Chengjia Wang , Giorgos Papanastasiou

Deformable templates are essential to large-scale medical image registration, segmentation, and population analysis. Current conventional and deep network-based methods for template construction use only regularized registration objectives…

Computer Vision and Pattern Recognition · Computer Science 2022-03-21 Neel Dey , Mengwei Ren , Adrian V. Dalca , Guido Gerig

Diffuse Optical Tomography (DOT) is an emerging technology in medical imaging which employs light in the NIR spectrum to estimate the distribution of optical coefficients in biological tissues for diagnostic and monitoring purposes. DOT…

Numerical Analysis · Mathematics 2022-05-27 Alessandro Benfenati , Giuseppe Bisazza , Paola Causin

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

Morphological analysis of longitudinal MR images plays a key role in monitoring disease progression for prostate cancer patients, who are placed under an active surveillance program. In this paper, we describe a learning-based image…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Qianye Yang , Yunguan Fu , Francesco Giganti , Nooshin Ghavami , Qingchao Chen , J. Alison Noble , Tom Vercauteren , Dean Barratt , Yipeng Hu

Shape information is a strong and valuable prior in segmenting organs in medical images. However, most current deep learning based segmentation algorithms have not taken shape information into consideration, which can lead to bias towards…

Computer Vision and Pattern Recognition · Computer Science 2022-07-07 Yuan Yao , Fengze Liu , Zongwei Zhou , Yan Wang , Wei Shen , Alan Yuille , Yongyi Lu

Image registration is a fundamental task in medical image analysis. Deformations are often closely related to the morphological characteristics of tissues, making accurate feature extraction crucial. Recent weakly supervised methods improve…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Yue He , Min Liu , Qinghao Liu , Jiazheng Wang , Yaonan Wang , Hang Zhang , Xiang Chen

Image registration (IR) is a process that deforms images to align them with respect to a reference space, making it easier for medical practitioners to examine various medical images in a standardized reference frame, such as having the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-11 Ahmad Hammoudeh , Stéphane Dupont

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak

In this work we address the problem of real-time dynamic MRI reconstruction. There are a handful of studies on this topic; these techniques are either based on compressed sensing or employ Kalman Filtering. These techniques cannot achieve…

Computer Vision and Pattern Recognition · Computer Science 2015-03-24 Angshul Majumdar

In the past, optimization-based registration models have used spatially-varying regularization to account for deformation variations in different image regions. However, deep learning-based registration models have mostly relied on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Junyu Chen , Yihao Liu , Yufan He , Yong Du

Recent deep learning-based methods have shown promising results and runtime advantages in deformable image registration. However, analyzing the effects of hyperparameters and searching for optimal regularization parameters prove to be too…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Tony C. W. Mok , Albert C. S. Chung

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

Medical image analysis relies on accurate segmentation, and benefits from controllable synthesis (of new training images). Yet both tasks of the cyclical pipeline face spatial imbalance: lesions occupy small regions against vast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Anugunj Naman , Ayushman Singh , Gaibo Zhang , Yaguang Zhang
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