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Contextual bandit algorithms are commonly used in digital health to recommend personalized treatments. However, to ensure the effectiveness of the treatments, patients are often requested to take actions that have no immediate benefit to…

Machine Learning · Computer Science 2024-03-14 Kyra Gan , Esmaeil Keyvanshokooh , Xueqing Liu , Susan Murphy

Learning personalized cancer treatment with machine learning holds great promise to improve cancer patients' chance of survival. Despite recent advances in machine learning and precision oncology, this approach remains challenging as…

Machine Learning · Computer Science 2022-07-12 Mingyu Lu , Yifang Chen , Su-In Lee

Clinical trials involving multiple treatments utilize randomization of the treatment assignments to enable the evaluation of treatment efficacies in an unbiased manner. Such evaluation is performed in post hoc studies that usually use…

Artificial Intelligence · Computer Science 2018-09-10 Yogatheesan Varatharajah , Brent Berry , Sanmi Koyejo , Ravishankar Iyer

We present substantial evidence demonstrating the benefits of integrating Large Language Models (LLMs) with a Contextual Multi-Armed Bandit framework. Contextual bandits have been widely used in recommendation systems to generate…

Machine Learning · Computer Science 2024-10-30 Parand A. Alamdari , Yanshuai Cao , Kevin H. Wilson

We introduce a unified framework that seamlessly integrates algorithmic recourse, contextual bandits, and large language models (LLMs) to support sequential decision-making in high-stakes settings such as personalized medicine. We first…

Artificial Intelligence · Computer Science 2026-01-21 Junyu Cao , Ruijiang Gao , Esmaeil Keyvanshokooh , Jianhao Ma

Precision oncology, the genetic sequencing of tumors to identify druggable targets, has emerged as the standard of care in the treatment of many cancers. Nonetheless, due to the pace of therapy development and variability in patient…

Machine Learning · Computer Science 2019-11-12 Niklas T. Rindtorff , MingYu Lu , Nisarg A. Patel , Huahua Zheng , Alexander D'Amour

Large language models (LLMs) exhibit diverse response behaviors, costs, and strengths, making it challenging to select the most suitable LLM for a given user query. We study the problem of adaptive multi-LLM selection in an online setting,…

Machine Learning · Computer Science 2025-06-24 Manhin Poon , XiangXiang Dai , Xutong Liu , Fang Kong , John C. S. Lui , Jinhang Zuo

Web-based applications such as chatbots, search engines and news recommendations continue to grow in scale and complexity with the recent surge in the adoption of LLMs. Online model selection has thus garnered increasing attention due to…

Machine Learning · Computer Science 2024-03-13 Yu Xia , Fang Kong , Tong Yu , Liya Guo , Ryan A. Rossi , Sungchul Kim , Shuai Li

As large language models (LLMs) become increasingly popular, there is a growing need to predict which out of a set of LLMs will yield a successful answer to a given query at low cost. This problem promises to become even more relevant as…

Computation and Language · Computer Science 2026-04-23 Baran Atalar , Eddie Zhang , Carlee Joe-Wong

Conversational contextual bandits elicit user preferences by occasionally querying for explicit feedback on key-terms to accelerate learning. However, there are aspects of existing approaches which limit their performance. First,…

Machine Learning · Computer Science 2023-10-03 Zhiyong Wang , Xutong Liu , Shuai Li , John C. S. Lui

We study how to learn optimal interventions sequentially given causal information represented as a causal graph along with associated conditional distributions. Causal modeling is useful in real world problems like online advertisement…

Machine Learning · Statistics 2020-06-12 Yangyi Lu , Amirhossein Meisami , Ambuj Tewari , Zhenyu Yan

We study Contextual Multi-Armed Bandits (CMABs) for non-episodic sequential decision making problems where the context includes both textual and numerical information (e.g., recommendation systems, dynamic portfolio adjustments, offer…

Artificial Intelligence · Computer Science 2026-04-08 Uljad Berdica , Fernando Acero , Anton Ipsen , Parisa Zehtabi , Michael Cashmore , Manuela Veloso

We introduce a new and completely online contextual bandit algorithm called Gated Linear Contextual Bandits (GLCB). This algorithm is based on Gated Linear Networks (GLNs), a recently introduced deep learning architecture with properties…

Machine Learning · Computer Science 2020-11-23 Eren Sezener , Marcus Hutter , David Budden , Jianan Wang , Joel Veness

We present BanditLP, a scalable multi-stakeholder contextual bandit framework that unifies neural Thompson Sampling for learning objective-specific outcomes with a large-scale linear program for constrained action selection at serving time.…

Machine Learning · Computer Science 2026-01-23 Phuc Nguyen , Benjamin Zelditch , Joyce Chen , Rohit Patra , Changshuai Wei

Speculative decoding has emerged as a popular method to accelerate the inference of Large Language Models (LLMs) while retaining their superior text generation performance. Previous methods either adopt a fixed speculative decoding…

Machine Learning · Computer Science 2025-11-21 Yunlong Hou , Fengzhuo Zhang , Cunxiao Du , Xuan Zhang , Jiachun Pan , Tianyu Pang , Chao Du , Vincent Y. F. Tan , Zhuoran Yang

Behavior change interventions are important to coordinate societal action across a wide array of important applications, including the adoption of electrified vehicles to reduce emissions. Prior work has demonstrated that interventions for…

Computation and Language · Computer Science 2024-11-01 Keiichi Namikoshi , David A. Shamma , Rumen Iliev , Jingchao Fang , Alexandre Filipowicz , Candice L Hogan , Charlene Wu , Nikos Arechiga

Sequential decision-making algorithms such as multi-armed bandits can find optimal personalized decisions, but are notoriously sample-hungry. In personalized medicine, for example, training a bandit from scratch for every patient is…

Machine Learning · Computer Science 2026-05-12 Ahmet Zahid Balcıoğlu , Newton Mwai , Emil Carlsson , Fredrik D. Johansson

Applying causal inference models in areas such as economics, healthcare and marketing receives great interest from the machine learning community. In particular, estimating the individual-treatment-effect (ITE) in settings such as precision…

Machine Learning · Computer Science 2019-10-17 Jeroen Berrevoets , Sam Verboven , Wouter Verbeke

The rapid advancement in large language models (LLMs) has brought forth a diverse range of models with varying capabilities that excel in different tasks and domains. However, selecting the optimal LLM for user queries often involves a…

Machine Learning · Computer Science 2025-02-06 Yang Li

The rise of large-scale pretrained models has made it feasible to generate predictive or synthetic features at low cost, raising the question of how to incorporate such surrogate predictions into downstream decision-making. We study this…

Machine Learning · Statistics 2026-04-03 Hao Yan , Heyan Zhang , Yongyi Guo
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