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Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

While large language models (LLMs) have demonstrated impressive capabilities across various natural language processing tasks by acquiring rich factual knowledge from their broad training data, their ability to synthesize and logically…

Computation and Language · Computer Science 2024-07-31 Tianshi Zheng , Jiaxin Bai , Yicheng Wang , Tianqing Fang , Yue Guo , Yauwai Yim , Yangqiu Song

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by integrating them with an external knowledge base to improve the answer relevance and accuracy. In real-world scenarios, beyond pure text, a substantial amount of…

Computation and Language · Computer Science 2025-10-07 Jiaru Zou , Dongqi Fu , Sirui Chen , Xinrui He , Zihao Li , Yada Zhu , Jiawei Han , Jingrui He

Large language models (LLMs) have shown impressive prowess in solving a wide range of tasks with world knowledge. However, it remains unclear how well LLMs are able to perceive their factual knowledge boundaries, particularly under…

Computation and Language · Computer Science 2024-11-20 Ruiyang Ren , Yuhao Wang , Yingqi Qu , Wayne Xin Zhao , Jing Liu , Hao Tian , Hua Wu , Ji-Rong Wen , Haifeng Wang

As Large Language Models (LLMs) continue to evolve, more are being designed to handle long-context inputs. Despite this advancement, most of them still face challenges in accurately handling long-context tasks, often showing the "lost in…

Computation and Language · Computer Science 2024-12-13 Yijiong Yu , Yongfeng Huang , Zhixiao Qi , Zhe Zhou

Retrieval Augmented Generation (RAG) systems have emerged as a powerful method for enhancing large language models (LLMs) with up-to-date information. However, the retrieval step in RAG can sometimes surface documents containing…

Computation and Language · Computer Science 2025-04-02 Vignesh Gokul , Srikanth Tenneti , Alwarappan Nakkiran

With the advancement of large language models (LLMs) and the expansion of their context windows, existing long-context benchmarks fall short in effectively evaluating the models' comprehension and reasoning abilities in extended texts.…

Computation and Language · Computer Science 2024-06-27 Lei Zhang , Yunshui Li , Ziqiang Liu , Jiaxi yang , Junhao Liu , Longze Chen , Run Luo , Min Yang

The Retrieval Augmented Generation (RAG) framework utilizes a combination of parametric knowledge and external knowledge to demonstrate state-of-the-art performance on open-domain question answering tasks. However, the RAG framework suffers…

Computation and Language · Computer Science 2024-10-25 Kiseung Kim , Jay-Yoon Lee

Existing large language models (LLMs) can only afford fix-sized inputs due to the input length limit, preventing them from utilizing rich long-context information from past inputs. To address this, we propose a framework, Language Models…

Computation and Language · Computer Science 2023-06-13 Weizhi Wang , Li Dong , Hao Cheng , Xiaodong Liu , Xifeng Yan , Jianfeng Gao , Furu Wei

Effective patient care in digital healthcare requires large language models (LLMs) that not only answer questions but also actively gather critical information through well-crafted inquiries. This paper introduces HealthQ, a novel framework…

Computation and Language · Computer Science 2025-02-26 Ziyu Wang , Hao Li , Di Huang , Hye-Sung Kim , Chae-Won Shin , Amir M. Rahmani

Large Language Models (LLMs) excel in data synthesis but can be inaccurate in domain-specific tasks, which retrieval-augmented generation (RAG) systems address by leveraging user-provided data. However, RAGs require optimization in both…

Computation and Language · Computer Science 2024-11-05 Kazi Ahmed Asif Fuad , Lizhong Chen

Large language models (LLMs) have demonstrated remarkable performance on question-answering (QA) tasks because of their superior capabilities in natural language understanding and generation. However, LLM-based QA struggles with complex QA…

Computation and Language · Computer Science 2025-09-23 Chuangtao Ma , Yongrui Chen , Tianxing Wu , Arijit Khan , Haofen Wang

Large language models (LLMs) have demonstrated remarkable progress in understanding long-context inputs. However, benchmarks for evaluating the long-context reasoning abilities of LLMs fall behind the pace. Existing benchmarks often focus…

Computation and Language · Computer Science 2025-11-19 Zhan Ling , Kang Liu , Kai Yan , Yifan Yang , Weijian Lin , Ting-Han Fan , Lingfeng Shen , Zhengyin Du , Jiecao Chen

Recent advancements in Large language models (LLMs) have demonstrated remarkable capabilities across diverse domains. While they exhibit strong zero-shot performance on various tasks, LLMs' effectiveness in music-related applications…

Computation and Language · Computer Science 2025-12-09 Daeyong Kwon , SeungHeon Doh , Juhan Nam

Retrieval-augmented generation (RAG) mitigates many problems of fully parametric language models, such as temporal degradation, hallucinations, and lack of grounding. In RAG, the model's knowledge can be updated from documents provided in…

Machine Learning · Computer Science 2024-10-10 Evgenii Kortukov , Alexander Rubinstein , Elisa Nguyen , Seong Joon Oh

Retrieval-Augmented Generation (RAG) effectively enhances Large Language Models (LLMs) by incorporating retrieved external knowledge into the generation process. Reasoning models improve LLM performance in multi-hop QA tasks, which require…

Computation and Language · Computer Science 2026-01-21 Guo Chen , Junjie Huang , Huaijin Xie , Fei Sun , Tao Jia

Large language models (LLMs) often exhibit limited performance on domain-specific tasks due to the natural disproportionate representation of specialized information in their training data and the static nature of these datasets. Knowledge…

Computation and Language · Computer Science 2025-09-30 Chaojun Nie , Jun Zhou , Guanxiang Wang , Shisong Wu , Zichen Wang

As Large Language Models (LLMs) increasingly address domain-specific problems, their application in the financial sector has expanded rapidly. Tasks that are both highly valuable and time-consuming, such as analyzing financial statements,…

Computation and Language · Computer Science 2024-11-28 Joohyun Lee , Minji Roh