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As large language models (LLMs) are increasingly deployed in healthcare, ensuring their safety, particularly within collaborative multi-agent configurations, is paramount. In this paper we introduce MedSentry, a benchmark comprising 5 000…

Multiagent Systems · Computer Science 2025-05-28 Kai Chen , Taihang Zhen , Hewei Wang , Kailai Liu , Xinfeng Li , Jing Huo , Tianpei Yang , Jinfeng Xu , Wei Dong , Yang Gao

Multi-agent cyberphysical systems enable new capabilities in efficiency, resilience, and security. The unique characteristics of these systems prompt a reevaluation of their security concepts, including their vulnerabilities, and mechanisms…

Retrieval-augmented LLMs are deployed for tasks where evidence quality determines action safety, yet evaluation protocols assume that single-turn robustness predicts robustness when evidence accumulates across turns. We show this assumption…

Artificial Intelligence · Computer Science 2026-05-27 Zhe Yu , Wenpeng Xing , Chen Ye , Xuyang Teng , Bo Yang , Changting Lin , Meng Han

What should a developer inspect before deploying an LLM agent: the model, the tool code, the deployment configuration, or all three? In practice, many security failures in agent systems arise not from model weights alone, but from the…

Cryptography and Security · Computer Science 2026-03-25 Haiyue Zhang , Yi Nian , Yue Zhao

This paper examines why safety mechanisms designed for human-model interaction do not scale to environments where large language models (LLMs) interact with each other. Most current governance practices still rely on single-agent safety…

Multiagent Systems · Computer Science 2025-12-03 Piercosma Bisconti , Marcello Galisai , Federico Pierucci , Marcantonio Bracale , Matteo Prandi

AI agents dynamically acquire tools, orchestrate sub-agents, and transact across organizational boundaries, yet no existing security layer verifies what an agent can do, whether it executed what it claims, or what happened in a multi-agent…

Cryptography and Security · Computer Science 2026-03-23 Ziling Zhou

As Large Language Model (LLM) agents become more widespread, associated misalignment risks increase. While prior research has studied agents' ability to produce harmful outputs or follow malicious instructions, it remains unclear how likely…

Context: Software vulnerabilities pose a significant threat to modern software systems, as evidenced by the growing number of reported vulnerabilities and cyberattacks. These escalating trends underscore the urgent need for effective…

Software Engineering · Computer Science 2025-07-01 Siyu Chen , Jiongyi Yang , Xiang Chen , Menglin Zheng , Minnan Wei , Xiaolin Ju

The rapid integration of Large Language Models (LLMs) across diverse sectors has marked a transformative era, showcasing remarkable capabilities in text generation and problem-solving tasks. However, this technological advancement is…

Cryptography and Security · Computer Science 2024-03-21 Rahul Pankajakshan , Sumitra Biswal , Yuvaraj Govindarajulu , Gilad Gressel

The rapid integration of Multimodal Large Language Models (MLLMs) into critical applications is increasingly hindered by persistent safety vulnerabilities. However, existing red-teaming benchmarks are often fragmented, limited to…

Cryptography and Security · Computer Science 2026-01-13 Xin Wang , Yunhao Chen , Juncheng Li , Yixu Wang , Yang Yao , Tianle Gu , Jie Li , Yan Teng , Yingchun Wang , Xia Hu

The rapid deployment of open-source frameworks has significantly advanced the development of modern multi-agent systems. However, expanded action spaces, including uncontrolled privilege exposure and hidden inter-system interactions, pose…

Computation and Language · Computer Science 2026-04-07 Wenhui Zhu , Xuanzhao Dong , Xiwen Chen , Rui Cai , Peijie Qiu , Zhipeng Wang , Oana Frunza , Shao Tang , Jindong Gu , Yalin Wang

Agentic workflows -- where multiple large language model (LLM) instances interact to solve tasks -- are increasingly built on feedback mechanisms, where one model evaluates and critiques another. Despite the promise of feedback-driven…

Artificial Intelligence · Computer Science 2025-06-05 Yifei Ming , Zixuan Ke , Xuan-Phi Nguyen , Jiayu Wang , Shafiq Joty

While multi-agent LLM systems show strong capabilities in various domains, they are highly vulnerable to adversarial and low-performing agents. To resolve this issue, in this paper, we introduce a general and adversary-resistant multi-agent…

Multiagent Systems · Computer Science 2025-06-02 Sana Ebrahimi , Mohsen Dehghankar , Abolfazl Asudeh

Large Language Model (LLM) agents are increasingly used to automate complex workflows, but integrating untrusted external data with privileged execution exposes them to severe security risks, particularly direct and indirect prompt…

Cryptography and Security · Computer Science 2026-04-28 Zonghao Ying , Haozheng Wang , Jiangfan Liu , Quanchen Zou , Aishan Liu , Jian Yang , Yaodong Yang , Xianglong Liu

Organisations are starting to adopt LLM-based AI agents, with their deployments naturally evolving from single agents towards interconnected, multi-agent networks. Yet a collection of safe agents does not guarantee a safe collection of…

Multiagent Systems · Computer Science 2025-08-11 Alistair Reid , Simon O'Callaghan , Liam Carroll , Tiberio Caetano

When combining Large Language Models (LLMs) with autonomous agents, used in network monitoring and decision-making systems, this will create serious security issues. In this research, the MAESTRO framework consisting of the seven layers…

Cryptography and Security · Computer Science 2025-08-15 Pallavi Zambare , Venkata Nikhil Thanikella , Ying Liu

The actions of intelligent agents, such as chatbots, recommender systems, and virtual assistants are typically not fully transparent to the user. Consequently, using such an agent involves the user exposing themselves to the risk that the…

Computer Science and Game Theory · Computer Science 2020-07-23 The Anh Han , Cedric Perret , Simon T. Powers

Current large language models (LLMs) excel in verifiable domains where outputs can be checked before action but prove less reliable for high-stakes strategic decisions with uncertain outcomes. This gap, driven by mutually reinforcing…

Artificial Intelligence · Computer Science 2025-11-12 Alejandro R. Jadad

Agentic AI systems, built upon large language models (LLMs) and deployed in multi-agent configurations, are redefining intelligence, autonomy, collaboration, and decision-making across enterprise and societal domains. This review presents a…

Artificial Intelligence · Computer Science 2025-12-19 Shaina Raza , Ranjan Sapkota , Manoj Karkee , Christos Emmanouilidis

Large language models increasingly rely on either reinforcement learning or multi-agent prompting to improve reasoning, yet these two paradigms remain difficult to combine. Directly applying single-agent reinforcement learning to multi-turn…

Artificial Intelligence · Computer Science 2026-05-28 Chusen Li , Zhou Liu , Shuigeng Zhou , Wentao Zhang