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We introduce MediX-R1, an open-ended Reinforcement Learning (RL) framework for medical multimodal large language models (MLLMs) that enables clinically grounded, free-form answers beyond multiple-choice formats. MediX-R1 fine-tunes a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Sahal Shaji Mullappilly , Mohammed Irfan Kurpath , Omair Mohamed , Mohamed Zidan , Fahad Khan , Salman Khan , Rao Anwer , Hisham Cholakkal

Medical vision-language models show strong potential for joint reasoning over medical images and clinical text, but their performance often degrades under domain shift caused by variations in imaging devices, acquisition protocols, and…

Machine Learning · Computer Science 2026-02-23 Melika Filvantorkaman , Mohsen Piri

Recent advances in general medical AI have made significant strides, but existing models often lack the reasoning capabilities needed for complex medical decision-making. This paper presents GMAI-VL-R1, a multimodal medical reasoning model…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Yanzhou Su , Tianbin Li , Jiyao Liu , Chenglong Ma , Junzhi Ning , Cheng Tang , Sibo Ju , Jin Ye , Pengcheng Chen , Ming Hu , Shixiang Tang , Lihao Liu , Bin Fu , Wenqi Shao , Xiaowei Hu , Xiangwen Liao , Yuanfeng Ji , Junjun He

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Developing 3D vision-language models with robust clinical reasoning remains a challenge due to the inherent complexity of volumetric medical imaging, the tendency of models to overfit superficial report patterns, and the lack of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Haoran Lai , Zihang Jiang , Kun Zhang , Qingsong Yao , Rongsheng Wang , Zhiyang He , Xiaodong Tao , Wei Wei , Shaohua Kevin Zhou

Large Language Models (LLMs) excel at reasoning and generation but are inherently limited by static pretraining data, resulting in factual inaccuracies and weak adaptability to new information. Retrieval-Augmented Generation (RAG) addresses…

Computation and Language · Computer Science 2025-11-03 Qi Luo , Xiaonan Li , Yuxin Wang , Tingshuo Fan , Yuan Li , Xinchi Chen , Xipeng Qiu

Multimodal Large Language Models (MLLMs) have recently been applied to universal multimodal retrieval, where Chain-of-Thought (CoT) reasoning improves candidate reranking. However, existing approaches remain largely language-driven, relying…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Dongyang Chen , Chaoyang Wang , Dezhao Su , Xi Xiao , Zeyu Zhang , Jing Xiong , Qing Li , Yuzhang Shang , Shichao Kan

Multimodal Large Language Models (MLLMs) have achieved remarkable progress in domains such as visual understanding and mathematical reasoning. However, their application in the medical domain is constrained by two key challenges: (1)…

Computation and Language · Computer Science 2025-10-09 Zeyu Liu , Zhitian Hou , Guanghao Zhu , Zhijie Sang , Congkai Xie , Hongxia Yang

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative…

Information Retrieval · Computer Science 2026-04-07 Xiangxu Zhang , Lei Li , Xiao Zhou , Zheng Liu

Large Language Models (LLMs) achieve impressive performance across many tasks but remain prone to hallucination, especially in long-form generation where redundant retrieved contexts and lengthy reasoning chains amplify factual errors.…

Computation and Language · Computer Science 2026-05-29 Yujie Feng , Jian Li , Zhihan Zhou , Pengfei Xu , Yujia Zhang , Xiaoyu Li , Xiaohui Zhou , Alan Zhao , Xi Chen , Xiao-Ming Wu

Medical retrieval-augmented generation (RAG) systems typically operate on text chunks extracted from biomedical literature, discarding the rich visual content (tables, figures, structured layouts) of original document pages. We propose…

Artificial Intelligence · Computer Science 2026-05-01 Xupeng Chen , Binbin Shi , Chenqian Le , Jiaqi Zhang , Kewen Wang , Ran Gong , Jinhan Zhang , Chihang Wang

Multimodal Large Language Models (MLLMs) have significantly advanced AI-assisted medical diagnosis, but they often generate factually inconsistent responses that deviate from established medical knowledge. Retrieval-Augmented Generation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Jinhong Wang , Tajamul Ashraf , Zongyan Han , Jorma Laaksonen , Rao Mohammad Anwer

Multimodal document retrieval systems enable information access across text, images, and layouts, benefiting various domains like document-based question answering, report analysis, and interactive content summarization. Rerankers improve…

Artificial Intelligence · Computer Science 2025-06-24 Mingjun Xu , Jinhan Dong , Jue Hou , Zehui Wang , Sihang Li , Zhifeng Gao , Renxin Zhong , Hengxing Cai

The success of DeepSeek-R1 demonstrates the immense potential of using reinforcement learning (RL) to enhance LLMs' reasoning capabilities. This paper introduces Retrv-R1, the first R1-style MLLM specifically designed for multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Lanyun Zhu , Deyi Ji , Tianrun Chen , Haiyang Wu , Shiqi Wang

Large Language Models (LLMs) have shown remarkable reasoning capabilities, while their practical applications are limited by severe factual hallucinations due to limitations in the timeliness, accuracy, and comprehensiveness of their…

Artificial Intelligence · Computer Science 2025-06-10 Xinyan Guan , Jiali Zeng , Fandong Meng , Chunlei Xin , Yaojie Lu , Hongyu Lin , Xianpei Han , Le Sun , Jie Zhou

Medical Vision-Language Models (VLMs) hold immense promise for complex clinical tasks, but their reasoning capabilities are often constrained by text-only paradigms that fail to ground inferences in visual evidence. This limitation not only…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Zheng Jiang , Heng Guo , Chengyu Fang , Changchen Xiao , Xinyang Hu , Lifeng Sun , Minfeng Xu

Reasoning has substantially improved the performance of large language models (LLMs) on complicated tasks. Central to the current reasoning studies, Process Reward Models (PRMs) offer a fine-grained evaluation of intermediate reasoning…

Machine Learning · Computer Science 2025-11-05 Qi Cao , Ruiyi Wang , Ruiyi Zhang , Sai Ashish Somayajula , Pengtao Xie

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

Computation and Language · Computer Science 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

The application of reinforcement learning (RL) to enhance the reasoning capabilities of Multimodal Large Language Models (MLLMs) constitutes a rapidly advancing research area. While MLLMs extend Large Language Models (LLMs) to handle…

Artificial Intelligence · Computer Science 2025-05-22 Guanghao Zhou , Panjia Qiu , Cen Chen , Jie Wang , Zheming Yang , Jian Xu , Minghui Qiu

Echocardiographic diagnosis is vital for cardiac screening yet remains challenging. Existing echocardiography foundation models do not effectively capture the relationships between quantitative measurements and clinical manifestations,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Yi Qin , Lehan Wang , Chenxu Zhao , Alex P. W. Lee , Xiaomeng Li