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We present a systematic evaluation framework - thirty-seven analyses, 153 statistical tests, four cell types, two perturbation modalities - for assessing mechanistic interpretability in single-cell foundation models. Applying this framework…

Genomics · Quantitative Biology 2026-02-20 Ihor Kendiukhov

Transformers, adapted from natural language processing, are emerging as a leading approach for graph representation learning. Contemporary graph transformers often treat nodes or edges as separate tokens. This approach leads to…

Machine Learning · Computer Science 2023-10-04 Zihan Pengmei , Zimu Li , Chih-chan Tien , Risi Kondor , Aaron R. Dinner

Geometric Attention (GA) specifies an attention layer by four independent inputs: a finite carrier (what indices are addressable), an evidence-kernel rule (how masked proto-scores and a link induce nonnegative weights), a probe family…

Machine Learning · Computer Science 2026-01-21 Luis Rosario Freytes

Learning from demonstrations is a common way for users to teach robots, but it is prone to spurious feature correlations. Recent work constructs state abstractions, i.e. visual representations containing task-relevant features, from…

We introduce methods for discovering and applying sparse feature circuits. These are causally implicated subnetworks of human-interpretable features for explaining language model behaviors. Circuits identified in prior work consist of…

Machine Learning · Computer Science 2025-03-28 Samuel Marks , Can Rager , Eric J. Michaud , Yonatan Belinkov , David Bau , Aaron Mueller

To perform few-shot learning, language models extract signals from a few input-label pairs, aggregate these into a learned prediction rule, and apply this rule to new inputs. How is this implemented in the forward pass of modern transformer…

Machine Learning · Computer Science 2025-10-10 Xinyan Hu , Kayo Yin , Michael I. Jordan , Jacob Steinhardt , Lijie Chen

Identifying words that impact a task's performance more than others is a challenge in natural language processing. Transformers models have recently addressed this issue by incorporating an attention mechanism that assigns greater attention…

Computation and Language · Computer Science 2023-03-15 Neşet Özkan Tan , Alex Yuxuan Peng , Joshua Bensemann , Qiming Bao , Tim Hartill , Mark Gahegan , Michael Witbrock

Sparse autoencoders (SAEs) have become an important tool for analyzing and interpreting the activation space of transformer-based language models (LMs). However, SAEs suffer several shortcomings that diminish their utility and internal…

Computation and Language · Computer Science 2025-06-27 Ryosuke Takahashi , Tatsuro Inaba , Kentaro Inui , Benjamin Heinzerling

Recursion is a prominent feature of human language, and fundamentally challenging for self-attention due to the lack of an explicit recursive-state tracking mechanism. Consequently, Transformer language models poorly capture long-tail…

Computation and Language · Computer Science 2023-10-31 Shikhar Murty , Pratyusha Sharma , Jacob Andreas , Christopher D. Manning

Understanding the reasons behind the exceptional success of transformers requires a better analysis of why attention layers are suitable for NLP tasks. In particular, such tasks require predictive models to capture contextual meaning which…

Machine Learning · Statistics 2024-05-20 Simone Bombari , Marco Mondelli

Large language models have found success by scaling up capabilities to work in general settings. The same can unfortunately not be said for interpretability methods. The current trend in mechanistic interpretability is to provide precise…

Machine Learning · Computer Science 2026-04-07 Jonathan Katzy , Razvan-Mihai Popescu , Erik Mekkes , Arie van Deursen , Maliheh Izadi

We propose a graph-oriented attention-based explainability method for tabular data. Tasks involving tabular data have been solved mostly using traditional tree-based machine learning models which have the challenges of feature selection and…

Machine Learning · Computer Science 2024-06-05 Andrea Treviño Gavito , Diego Klabjan , Jean Utke

What latent features are encoded in language model (LM) representations? Recent work on training sparse autoencoders (SAEs) to disentangle interpretable features in LM representations has shown significant promise. However, evaluating the…

With the advent of large models based on the Transformer architecture, researchers have observed an anomalous phenomenon in the Attention mechanism--there is a very high attention on the first element, which is prevalent across…

Machine Learning · Computer Science 2024-07-04 Ruiqing Yan , Xingbo Du , Haoyu Deng , Linghan Zheng , Qiuzhuang Sun , Jifang Hu , Yuhang Shao , Penghao Jiang , Jinrong Jiang , Lian Zhao

Trained Transformers have been shown to compute abstract features that appear redundant for predicting the immediate next token. We identify which components of the gradient signal from the next-token prediction objective give rise to this…

Machine Learning · Computer Science 2026-03-17 Mark Rofin , Jalal Naghiyev , Michael Hahn

Pre-trained transformer models shine in many natural language processing tasks and therefore are expected to bear the representation of the input sentence or text meaning. These sentence-level embeddings are also important in…

Computation and Language · Computer Science 2025-02-21 Lukas Stankevičius , Mantas Lukoševičius

Adverse Event (ADE) extraction is one of the core tasks in digital pharmacovigilance, especially when applied to informal texts. This task has been addressed by the Natural Language Processing community using large pre-trained language…

Computation and Language · Computer Science 2023-06-09 Simone Scaboro , Beatrice Portellia , Emmanuele Chersoni , Enrico Santus , Giuseppe Serra

To improve the generalization of the representations for natural language processing tasks, words are commonly represented using vectors, where distances among the vectors are related to the similarity of the words. While word2vec, the…

Computation and Language · Computer Science 2020-03-20 Canlin Zhang , Xiuwen Liu , Daniel Bis

The advent of recurrent neural networks for handwriting recognition marked an important milestone reaching impressive recognition accuracies despite the great variability that we observe across different writing styles. Sequential…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Lei Kang , Pau Riba , Marçal Rusiñol , Alicia Fornés , Mauricio Villegas

Supervised training of abstractive language generation models results in learning conditional probabilities over language sequences based on the supervised training signal. When the training signal contains a variety of writing styles, such…

Computation and Language · Computer Science 2018-04-12 Ye Zhang , Nan Ding , Radu Soricut