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Related papers: OncoReason: Structuring Clinical Reasoning in LLMs…

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Chain-of-thought (CoT) has emerged as a critical mechanism for enhancing reasoning capabilities in large language models (LLMs), with self-consistency demonstrating notable promise in boosting performance. However, inherent linguistic…

Computation and Language · Computer Science 2025-04-03 Zhiwei Yu , Tuo Li , Changhong Wang , Hui Chen , Lang Zhou

Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis. However, their application in gastrointestinal endoscopy is currently hindered by two critical limitations: the misalignment between…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Huan Zheng , Yucheng Zhou , Tianyi Yan , Dubing Chen , Hongbo Lu , Wenlong Liao , Tao He , Pai Peng , Jianbing Shen

Large language models (LLMs) face significant challenges in specialized biomedical tasks due to the inherent complexity of medical reasoning and the sensitive nature of clinical data. Existing LLMs often struggle with intricate medical…

Computation and Language · Computer Science 2026-05-12 Zongxian Yang , Jiayu Qian , Kay Chen Tan , Hau-San Wong , Yulong Chen , Haoyu Zhang , Zhi-An Huang

We present a novel framework addressing a critical vulnerability in Large Language Models (LLMs): the prevalence of factual inaccuracies within intermediate reasoning steps despite correct final answers. This phenomenon poses substantial…

Computation and Language · Computer Science 2025-08-05 Rui Jiao , Yue Zhang , Jinku Li

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

Accurate disease classification from radiology reports is essential for many applications. While supervised fine-tuning (SFT) of lightweight LLMs improves accuracy, it can degrade reasoning. We propose a two-stage approach: SFT on disease…

Artificial Intelligence · Computer Science 2026-04-22 Yishu Wei , Yi Lin , Adam Flanders , George Shih , Yifan Peng

Acute poly-substance intoxication requires rapid, life-saving decisions under substantial uncertainty, as clinicians must rely on incomplete ingestion details and nonspecific symptoms. Effective diagnostic reasoning in this chaotic…

Computation and Language · Computer Science 2026-04-01 Nico Oberländer , David Bani-Harouni , Tobias Zellner , Nassir Navab , Florian Eyer , Matthias Keicher

Recent Reinforcement Learning (RL) advances for Large Language Models (LLMs) have improved reasoning tasks, yet their resource-constrained application to medical imaging remains underexplored. We introduce ChexReason, a vision-language…

Lung cancer clinical decision support demands precise reasoning across complex, multi-stage oncological workflows. Existing multimodal large language models (MLLMs) fail to handle guideline-constrained staging and treatment reasoning. We…

Tabular prediction traditionally relies on gradient-boosted decision trees and deep learning models, which excel in specific tasks but lack interpretability and transferability. Reasoning large language models (LLMs) promise cross-task…

Machine Learning · Computer Science 2026-03-11 Pengxiang Cai , Zihao Gao , Wanchen Lian , Jintai Chen

Drug toxicity remains a major challenge in pharmaceutical development. Recent machine learning models have improved in silico toxicity prediction, but their reliance on annotated data and lack of interpretability limit their applicability.…

Machine Learning · Computer Science 2025-11-06 Jueon Park , Yein Park , Minju Song , Soyon Park , Donghyeon Lee , Seungheun Baek , Jaewoo Kang

Large Language Models (LLMs) have shown impressive reasoning capabilities in well-defined problems with clear solutions, such as mathematics and coding. However, they still struggle with complex real-world scenarios like business…

Computation and Language · Computer Science 2025-05-29 Xiaoqian Liu , Ke Wang , Yongbin Li , Yuchuan Wu , Wentao Ma , Aobo Kong , Fei Huang , Jianbin Jiao , Junge Zhang

In recent years, significant progress has been made in the field of surgical scene understanding, particularly in the task of Visual Question Localized-Answering in robotic surgery (Surgical-VQLA). However, existing Surgical-VQLA models…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Pengfei Hao , Shuaibo Li , Hongqiu Wang , Zhizhuo Kou , Junhang Zhang , Guang Yang , Lei Zhu

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

Large language models (LLMs) are increasingly used for high-stakes decision-making, yet existing approaches struggle to reconcile scalability, interpretability, and reproducibility. Black-box models obscure their reasoning, while recent…

While large language models (LLMs) have shown strong performance in math and logic reasoning, their ability to handle combinatorial optimization (CO) -- searching high-dimensional solution spaces under hard constraints -- remains…

Artificial Intelligence · Computer Science 2026-04-13 Xia Jiang , Jing Chen , Cong Zhang , Jie Gao , Chengpeng Hu , Chenhao Zhang , Yaoxin Wu , Yingqian Zhang

The integration of Large Language Models (LLMs) into biomedical research offers new opportunities for domainspecific reasoning and knowledge representation. However, their performance depends heavily on the semantic quality of training…

Despite the wide adoption of Large Language Models (LLM)s, clinical decision support systems face a critical challenge: achieving high predictive accuracy while generating explanations aligned with the predictions. Current approaches suffer…

Artificial Intelligence · Computer Science 2026-05-07 H M Quamran Hasan , Housam Khalifa Bashier , Jiayi Dai , Mi-Young Kim , Randy Goebel

Large language models (LLMs) with Chain-of-thought (CoT) have recently emerged as a powerful technique for eliciting reasoning to improve various downstream tasks. As most research mainly focuses on English, with few explorations in a…

Computation and Language · Computer Science 2024-07-11 Huiyuan Lai , Malvina Nissim

Logical reasoning is a critical benchmark for evaluating the capabilities of large language models (LLMs), as it reflects their ability to derive valid conclusions from given premises. While the combination of test-time scaling with…

Computation and Language · Computer Science 2025-08-28 Ramya Keerthy Thatikonda , Wray Buntine , Ehsan Shareghi