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Large Language Models (LLMs) has made significant progress in a number of professional fields, including medicine, law, and finance. However, in traditional Chinese medicine (TCM), there are challenges such as the essential differences…

Computation and Language · Computer Science 2024-06-25 Heyi Zhang , Xin Wang , Zhaopeng Meng , Zhe Chen , Pengwei Zhuang , Yongzhe Jia , Dawei Xu , Wenbin Guo

Traditional Chinese Medicine (TCM), with a history spanning over two millennia, plays a role in global healthcare. However, applying large language models (LLMs) to TCM remains challenging due to its reliance on holistic reasoning, implicit…

Computation and Language · Computer Science 2025-10-21 Jiacheng Xie , Yang Yu , Yibo Chen , Hanyao Zhang , Lening Zhao , Jiaxuan He , Lei Jiang , Xiaoting Tang , Guanghui An , Dong Xu

Traditional Chinese Medicine (TCM), as an effective alternative medicine, has been receiving increasing attention. In recent years, the rapid development of large language models (LLMs) tailored for TCM has highlighted the urgent need for…

Computation and Language · Computer Science 2025-10-28 Jiacheng Xie , Yang Yu , Ziyang Zhang , Shuai Zeng , Jiaxuan He , Ayush Vasireddy , Xiaoting Tang , Congyu Guo , Lening Zhao , Congcong Jing , Guanghui An , Dong Xu

Recent advances in large language models (LLMs) have shown strong reasoning capabilities through large-scale pretraining and post-training reinforcement learning, demonstrated by DeepSeek-R1. However, current post-training methods, such as…

Artificial Intelligence · Computer Science 2025-12-04 Boyang Gu , Hongjian Zhou , Bradley Max Segal , Jinge Wu , Zeyu Cao , Hantao Zhong , Lei Clifton , Fenglin Liu , David A. Clifton

Large Language Models (LLMs) often exhibit implicit biases and discriminatory tendencies that reflect underlying social stereotypes. While recent alignment techniques such as RLHF and DPO have mitigated some of these issues, they remain…

Computation and Language · Computer Science 2025-11-11 Deng Yixuan , Ji Xiaoqiang

Large Language Models (LLMs) have demonstrated remarkable capabilities in modern medicine, yet their application in Traditional Chinese Medicine (TCM) remains severely limited by the absence of standardized benchmarks and the scarcity of…

Computation and Language · Computer Science 2025-12-29 Zihao Cheng , Yuheng Lu , Huaiqian Ye , Zeming Liu , Minqi Wang , Jingjing Liu , Zihan Li , Wei Fan , Yuanfang Guo , Ruiji Fu , Shifeng She , Gang Wang , Yunhong Wang

Search agents extend Large Language Models (LLMs) beyond static parametric knowledge by enabling access to up-to-date and long-tail information unavailable during pretraining. While reinforcement learning has been widely adopted for…

Machine Learning · Computer Science 2026-04-21 Junzhe Wang , Zhiheng Xi , Yajie Yang , Hao Luo , Shihan Dou , Tao Gui , Qi Zhang

The Group Relative Policy Optimization (GRPO), a reinforcement learning method used to fine-tune large language models (LLMs), has proved its effectiveness in practical applications such as DeepSeek-R1. It raises a question whether GRPO can…

Machine Learning · Computer Science 2025-11-20 Yanchen Xu , Ziheng Jiao , Hongyuan Zhang , Xuelong Li

Recent advances in Large Language Model (LLM) agents have demonstrated their promising general capabilities. However, their performance in specialized real-world domains often degrades due to challenges in effectively integrating external…

Computation and Language · Computer Science 2025-10-10 Yuzheng Cai , Siqi Cai , Yuchen Shi , Zihan Xu , Lichao Chen , Yulei Qin , Xiaoyu Tan , Gang Li , Zongyi Li , Haojia Lin , Yong Mao , Ke Li , Xing Sun

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Large Language Models (LLMs) are increasingly deployed in business-critical domains such as finance, education, healthcare, and customer support, where users expect consistent and reliable recommendations. Yet LLMs often exhibit variability…

Machine Learning · Computer Science 2026-04-20 Sonal Prabhune , Balaji Padmanabhan , Kaushik Dutta

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Large language models (LLMs) excel in various NLP tasks and modern medicine, but their evaluation in traditional Chinese medicine (TCM) is underexplored. To address this, we introduce TCM3CEval, a benchmark assessing LLMs in TCM across…

Computation and Language · Computer Science 2025-03-11 Tianai Huang , Lu Lu , Jiayuan Chen , Lihao Liu , Junjun He , Yuping Zhao , Wenchao Tang , Jie Xu

Large language models (LLMs) have performed remarkably well in various natural language processing tasks by benchmarking, including in the Western medical domain. However, the professional evaluation benchmarks for LLMs have yet to be…

Computation and Language · Computer Science 2024-06-04 Wenjing Yue , Xiaoling Wang , Wei Zhu , Ming Guan , Huanran Zheng , Pengfei Wang , Changzhi Sun , Xin Ma

Large Language Models (LLMs) struggle with accuracy, domain-specific reasoning, and interpretability in vertical domains. Traditional preference alignment methods like Reinforcement Learning from Human Feedback (RLHF) and Direct Preference…

Computation and Language · Computer Science 2025-06-04 Qihang Yan , Xinyu Zhang , Luming Guo , Qi Zhang , Feifan Liu

This paper explores the application of prompt engineering to enhance the performance of large language models (LLMs) in the domain of Traditional Chinese Medicine (TCM). We propose TCM-Prompt, a framework that integrates various pre-trained…

Computation and Language · Computer Science 2024-10-28 Yirui Chen , Qinyu Xiao , Jia Yi , Jing Chen , Mengyang Wang

We propose reinforcement learning (RL) strategies tailored for reasoning in large language models (LLMs) under strict memory and compute limits, with a particular focus on compatibility with LoRA fine-tuning. Building on early policy…

Machine Learning · Computer Science 2025-06-13 Alan Lee , Harry Tong

Recent advances in large language models (LLMs) have broadened their applicability across diverse tasks, yet specialized domains still require targeted post training. Among existing methods, Group Relative Policy Optimization (GRPO) stands…

Machine Learning · Computer Science 2025-08-08 Ziyin Gu , Jingyao Wang , Ran Zuo , Chuxiong Sun , Zeen Song , Changwen Zheng , Wenwen Qiang

The recently unprecedented advancements in Large Language Models (LLMs) have propelled the medical community by establishing advanced medical-domain models. However, due to the limited collection of medical datasets, there are only a few…

Computation and Language · Computer Science 2024-06-10 Ping Yu , Kaitao Song , Fengchen He , Ming Chen , Jianfeng Lu

Traditional Chinese Medicine (TCM) is a holistic medical system with millennia of accumulated clinical experience, playing a vital role in global healthcare-particularly across East Asia. However, the implicit reasoning, diverse textual…

Computation and Language · Computer Science 2025-06-03 Shufeng Kong , Xingru Yang , Yuanyuan Wei , Zijie Wang , Hao Tang , Jiuqi Qin , Shuting Lan , Yingheng Wang , Junwen Bai , Zhuangbin Chen , Zibin Zheng , Caihua Liu , Hao Liang
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