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This paper presents DDTracking, a novel deep generative framework for diffusion MRI tractography that formulates streamline propagation as a conditional denoising diffusion process. In DDTracking, we introduce a dual-pathway encoding…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Yijie Li , Wei Zhang , Xi Zhu , Ye Wu , Yogesh Rathi , Lauren J. O'Donnell , Fan Zhang

Accurately identifying white matter tracts in medical images is essential for various applications, including surgery planning and tract-specific analysis. Supervised machine learning models have reached state-of-the-art solving this task…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Robin Peretzke , Klaus Maier-Hein , Jonas Bohn , Yannick Kirchhoff , Saikat Roy , Sabrina Oberli-Palma , Daniela Becker , Pavlina Lenga , Peter Neher

Tensor-based morphometry (TBM) aims at showing local differences in brain volumes with respect to a common template. TBM images are smooth but they exhibit (especially in diseased groups) higher values in some brain regions called lateral…

Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Traumatic Brain Injuries (TBIs) resulting from Road Traffic Crashes (RTCs) can have fatal and disabling effects on patients. In this study, we evaluated the TBIs outcomes of patients involved in RTCs and identify key contributing factors…

Applications · Statistics 2024-11-05 Azka Rodoshi Oishi , Md Jamil Ahsan , Azka Sejuti , B M Tazbiul Hassan Anik

Diffusion tensor imaging (DTI) is a novel modality of magnetic resonance imaging that allows noninvasive mapping of the brain's white matter. A particular map derived from DTI measurements is a map of water principal diffusion directions,…

Applications · Statistics 2008-12-18 Armin Schwartzman , Robert F. Dougherty , Jonathan E. Taylor

Automated segmentation of medical imaging is of broad interest to clinicians and machine learning researchers alike. The goal of segmentation is to increase efficiency and simplicity of visualization and quantification of regions of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-04 Shruti Jadon , Owen P. Leary , Ian Pan , Tyler J. Harder , David W. Wright , Lisa H. Merck , Derek L. Merck

We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…

Medical Physics · Physics 2024-08-21 Ting Gong , Merlin J. Fair , Kawin Setsompop , Hui Zhang

Multimodal neuroimaging modeling has becomes a widely used approach but confronts considerable challenges due to heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability…

Neurons and Cognition · Quantitative Biology 2025-04-15 Gang Qu , Ziyu Zhou , Vince D. Calhoun , Aiying Zhang , Yu-Ping Wang

Introduction: Tuberculous meningitis (TBM) is a serious brain infection caused by Mycobacterium tuberculosis, characterized by inflammation of the meninges covering the brain and spinal cord. Diagnosis often requires invasive lumbar…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Snigdha Agarwal , Ganaraja V H , Neelam Sinha , Abhilasha Indoria , Netravathi M , Jitender Saini

Tractography parcellation classifies streamlines reconstructed from diffusion MRI into anatomically defined fiber tracts for clinical and research applications. However, clinical scans often have incomplete fields of view (FOV) where brain…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Yuqian Chen , Leo Zekelman , Yui Lo , Suheyla Cetin-Karayumak , Tengfei Xue , Yogesh Rathi , Nikos Makris , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

Divergent brain connectivity is thought to underlie the behavioral and cognitive symptoms observed in many neurodevelopmental disorders. Quantifying divergence from neurotypical connectivity patterns offers a promising pathway to inform…

Neurons and Cognition · Quantitative Biology 2024-11-19 Rui Sherry Shen , Yusuf Osmanlıoğlu , Drew Parker , Darien Aunapu , Benjamin E. Yerys , Birkan Tunç , Ragini Verma

Numerous studies on text-to-image (T2I) generative models have utilized cross-attention maps to boost application performance and interpret model behavior. However, the distinct characteristics of attention maps from different attention…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Jungwon Park , Jungmin Ko , Dongnam Byun , Wonjong Rhee

Diffusion kurtosis imaging (DKI), is an imaging modality that yields novel disease biomarkers and in combination with nervous tissue modeling, provides access to microstructural parameters. Recently, DKI and subsequent estimation of…

Quantitative Methods · Quantitative Biology 2019-04-09 Andrey Chuhutin , Brian Hansen , Agnieszka Wlodarczyk , Trevor Owens , Noam Shemesh , Sune Nørhøj Jespersen

Intracranial hemorrhage (ICH) secondary to Traumatic Brain Injury (TBI) represents a critical diagnostic challenge, with approximately 64,000 TBI-related deaths annually in the United States. Current diagnostic modalities including Computed…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Phat Tran , Enbai Kuang , Fred Xu

Mild traumatic brain injury (mTBI) is a prevalent condition that remains difficult to diagnose in its early stages. Oculomotor dysfunction is a well-established marker of mTBI, motivating the development of portable tools that capture both…

Signal Processing · Electrical Eng. & Systems 2026-05-15 Shantanu Sarkar , Sai Shashank Gandavarapu , Jeff Feng , Saurabh Prasad , Reza Khanbabaie , Jose L. Contreras-Vidal

Understanding brain connectivity has become one of the most important issues in neuroscience. But connectivity data can reflect either the functional relationships of the brain activities or the anatomical properties between brain areas.…

Neurons and Cognition · Quantitative Biology 2015-04-13 Tiago Simas , Mario Chavez , Pablo Rodriguez , Albert Diaz-Guilera

Medical ultrasound provides images which are the spatial map of the tissue echogenicity. Unfortunately, an ultrasound image is a low-quality version of the expected Tissue Reflectivity Function (TRF) mainly due to the non-ideal Point Spread…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sobhan Goudarzi , Hassan Rivaz

This study investigates optical activity and quantum transport in twisted bilayer graphene (TBG) systems, demonstrating that the former results from spatial dispersion effects. The transfer matrix method is used to solve the propagation of…

Mesoscale and Nanoscale Physics · Physics 2023-05-31 S. Ta Ho , V. Nam Do

In this paper, we develop an analytical approach for estimating brain connectivity networks that accounts for subject heterogeneity. More specifically, we consider a novel extension of a multi-subject Bayesian vector autoregressive model…