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Frontier large language models (LLMs) are developed by researchers and practitioners with skewed cultural backgrounds and on datasets with skewed sources. However, LLMs' (lack of) multicultural knowledge cannot be effectively assessed with…

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Large language model agents are becoming increasingly capable at web-centric tasks such as information retrieval, complex reasoning. These emerging capabilities have given rise to surge research interests in developing LLM agent for…

Computation and Language · Computer Science 2026-04-02 Yu Li , Lehui Li , Lin Chen , Qingmin Liao , Fengli Xu , Yong Li

Sequential sentence classification (SSC) in scientific publications is crucial for supporting downstream tasks such as fine-grained information retrieval and extractive summarization. However, current SSC methods are constrained by model…

Computation and Language · Computer Science 2024-12-02 Mengfei Lan , Lecheng Zheng , Shufan Ming , Halil Kilicoglu

We introduce Biomed-Enriched, a biomedical text dataset constructed from PubMed via a two-stage annotation process. In the first stage, a large language model annotates 400K paragraphs from PubMed scientific articles, assigning scores for…

Computation and Language · Computer Science 2025-06-26 Rian Touchent , Nathan Godey , Eric de la Clergerie

Annotation bias in NLP datasets remains a major challenge for developing multilingual Large Language Models (LLMs), particularly in culturally diverse settings. Bias from task framing, annotator subjectivity, and cultural mismatches can…

Computation and Language · Computer Science 2025-11-19 Xia Cui , Ziyi Huang , Naeemeh Adel

This paper presents the formal release of MedMentions, a new manually annotated resource for the recognition of biomedical concepts. What distinguishes MedMentions from other annotated biomedical corpora is its size (over 4,000 abstracts…

Computation and Language · Computer Science 2019-02-26 Sunil Mohan , Donghui Li

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Biomedical documents such as Electronic Health Records (EHRs) contain a large amount of information in an unstructured format. The data in EHRs is a hugely valuable resource documenting clinical narratives and decisions, but whilst the text…

Computation and Language · Computer Science 2019-12-24 Zeljko Kraljevic , Daniel Bean , Aurelie Mascio , Lukasz Roguski , Amos Folarin , Angus Roberts , Rebecca Bendayan , Richard Dobson

Novel contexts may often arise in complex querying scenarios such as in evidence-based medicine (EBM) involving biomedical literature, that may not explicitly refer to entities or canonical concept forms occurring in any fact- or rule-based…

Computation and Language · Computer Science 2019-11-12 Manirupa Das , Juanxi Li , Eric Fosler-Lussier , Simon Lin , Soheil Moosavinasab , Steve Rust , Yungui Huang , Rajiv Ramnath

As Large Language Models (LLMs) rapidly evolve, their influence in science is becoming increasingly prominent. The emerging capabilities of LLMs in task generalization and free-form dialogue can significantly advance fields like chemistry…

Computation and Language · Computer Science 2024-02-21 Yin Fang , Kangwei Liu , Ningyu Zhang , Xinle Deng , Penghui Yang , Zhuo Chen , Xiangru Tang , Mark Gerstein , Xiaohui Fan , Huajun Chen

This paper is on active learning where the goal is to reduce the data annotation burden by interacting with a (human) oracle during training. Standard active learning methods ask the oracle to annotate data samples. Instead, we take a…

Computer Vision and Pattern Recognition · Computer Science 2017-08-03 Miriam W. Huijser , Jan C. van Gemert

Cellular image segmentation is essential for quantitative biology yet remains difficult due to heterogeneous modalities, morphological variability, and limited annotations. We present GenCellAgent, a training-free multi-agent framework that…

Quantitative Methods · Quantitative Biology 2026-05-12 Xi Yu , Yang Yang , Qun Liu , Yonghua Du , Sean McSweeney , Yuewei Lin

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Large language models (LLMs) present a promising yet challenging frontier for automated source citation in scientific communication. Previous approaches to citation generation have been limited by citation ambiguity and LLM…

Computation and Language · Computer Science 2025-04-14 Yash Saxena , Deepa Tilwani , Ali Mohammadi , Edward Raff , Amit Sheth , Srinivasan Parthasarathy , Manas Gaur

Suicidal ideation detection is critical for real-time suicide prevention, yet its progress faces two under-explored challenges: limited language coverage and unreliable annotation practices. Most available datasets are in English, but even…

Computation and Language · Computer Science 2025-07-22 Amina Dzafic , Merve Kavut , Ulya Bayram

Large Language Models (LLMs) can adapt to new tasks via in-context learning (ICL). ICL is efficient as it does not require any parameter updates to the trained LLM, but only few annotated examples as input for the LLM. In this work, we…

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

Recent years showed a strong increase in biomedical sciences and an inherent increase in publication volume. Extraction of specific information from these sources requires highly sophisticated text mining and information extraction tools.…

Computation and Language · Computer Science 2020-04-09 Johannes Kirschnick , Philippe Thomas , Roland Roller , Leonhard Hennig

The question-answering system for Life science research, which is characterized by the rapid pace of discovery, evolving insights, and complex interactions among knowledge entities, presents unique challenges in maintaining a comprehensive…

Computation and Language · Computer Science 2024-08-15 Chengrui Wang , Qingqing Long , Meng Xiao , Xunxin Cai , Chengjun Wu , Zhen Meng , Xuezhi Wang , Yuanchun Zhou
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