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Electrocardiography (ECG) is a non-invasive tool for predicting cardiovascular diseases (CVDs). Current ECG-based diagnosis systems show promising performance owing to the rapid development of deep learning techniques. However, the label…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Rushuang Zhou , Lei Lu , Zijun Liu , Ting Xiang , Zhen Liang , David A. Clifton , Yining Dong , Yuan-Ting Zhang

Cardiovascular disease (CVD) prediction remains a tremendous challenge due to its multifactorial etiology and global burden of morbidity and mortality. Despite the growing availability of genomic and electrophysiological data, extracting…

Machine Learning · Computer Science 2025-08-12 Niranjana Arun Menon , Iqra Farooq , Yulong Li , Sara Ahmed , Yutong Xie , Muhammad Awais , Imran Razzak

Reliable risk assessment for carotid atheromatous disease remains a major clinical challenge, as it requires integrating diverse clinical and imaging information in a manner that is transparent and interpretable to clinicians. This study…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Daphne Tsolissou , Theofanis Ganitidis , Konstantinos Mitsis , Stergios CHristodoulidis , Maria Vakalopoulou , Konstantina Nikita

The label scarcity problem is the main challenge that hinders the wide application of deep learning systems in automatic cardiovascular diseases (CVDs) detection using electrocardiography (ECG). Tuning pre-trained models alleviates this…

Machine Learning · Computer Science 2024-11-18 Rushuang Zhou , Lei Clifton , Zijun Liu , Kannie W. Y. Chan , David A. Clifton , Yuan-Ting Zhang , Yining Dong

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

Machine Learning · Computer Science 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

Due to the high human cost of annotation, it is non-trivial to curate a large-scale medical dataset that is fully labeled for all classes of interest. Instead, it would be convenient to collect multiple small partially labeled datasets from…

Machine Learning · Computer Science 2022-04-20 Nanqing Dong , Jiayi Wang , Irina Voiculescu

Automated analysis of 12-lead electrocardiogram (ECG) plays a crucial role in the early screening and management of cardiovascular diseases (CVDs). In practice, it is common to see multiple co-occurring cardiac disorders, i.e., multi-label…

Signal Processing · Electrical Eng. & Systems 2023-06-07 Eedara Prabhakararao , Samarendra Dandapt

Vision-language models (VLMs) pre-trained on large, heterogeneous data sources are becoming increasingly popular, providing rich multi-modal embeddings that enable efficient transfer to new tasks. A particularly relevant application is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Julio Silva-Rodríguez , Ender Konukoglu

Electrocardiogram (ECG) signal is one of the most effective sources of information mainly employed for the diagnosis and prediction of cardiovascular diseases (CVDs) connected with the abnormalities in heart rhythm. Clearly, single modality…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Thinh Phan , Duc Le , Patel Brijesh , Donald Adjeroh , Jingxian Wu , Morten Olgaard Jensen , Ngan Le

Recent advances in large language models (LLMs) have enabled the development of multimodal medical AI. While models such as MedGemini achieve high accuracy on VQA tasks like USMLE MM, their performance on ECG based tasks remains limited,…

Machine Learning · Computer Science 2026-02-12 Junichiro Takahashi , Masataka Sato , Satoshi Kodeta , Norihiko Takeda

Timely identification and accurate risk stratification of cardiovascular disease (CVD) remain essential for reducing global mortality. While existing prediction models primarily leverage structured data, unstructured clinical notes contain…

Computation and Language · Computer Science 2025-07-16 Haowei Yang , Ziyu Shen , Junli Shao , Luyao Men , Xinyue Han , Jing Dong

Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, highlighting the critical need for efficient and accurate diagnostic tools. Electrocardiograms (ECGs) are indispensable in diagnosing various heart conditions;…

Signal Processing · Electrical Eng. & Systems 2025-04-24 Lei Kang , Xuanshuo Fu , Javier Vazquez-Corral , Ernest Valveny , Dimosthenis Karatzas

Electrocardiography (ECG) plays a central role in cardiovascular diagnostics, yet existing automated approaches often struggle to generalize across clinical tasks and offer limited support for open-ended reasoning. We present HeartLLM, a…

Artificial Intelligence · Computer Science 2026-01-27 Jinning Yang , Wenjie Sun , Wen Shi

Label ambiguity is an inherent problem in real-world electrocardiogram (ECG) diagnosis, arising from overlapping conditions and diagnostic disagreement. However, current ECG models are trained under the assumption of clean and non-ambiguous…

Machine Learning · Computer Science 2025-12-15 Sana Rahmani , Javad Hashemi , Ali Etemad

Medical Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities across diverse healthcare tasks. However, current post-training strategies, such as supervised fine-tuning and reinforcement learning, heavily depend…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Dunyuan Xu , Xikai Yang , Juzheng Miao , Yaoqian Li , Jinpeng Li , Pheng-Ann Heng

Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a…

Machine Learning · Computer Science 2026-01-13 Rohit Kaushik , Eva Kaushik

Computer-aided diagnosis systems must make critical decisions from medical images that are often noisy, ambiguous, or conflicting, yet today's models are trained on overly simplistic labels that ignore diagnostic uncertainty. One-hot labels…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Ang Nan Gu , Michael Tsang , Hooman Vaseli , Purang Abolmaesumi , Teresa Tsang

Cardiovascular disease (CVD) persists as a primary cause of death on a global scale, which requires more effective and timely detection methods. Traditional supervised learning approaches for CVD detection rely heavily on large-labeled…

Quantitative Methods · Quantitative Biology 2024-12-17 Shaohan Chen , Zheyan Liu , Huili Zheng , Qimin Zhang , Yiru Gong

The major challenge of learning from multi-label data has arisen from the overwhelming size of label space which makes this problem NP-hard. This problem can be alleviated by gradually involving easy to hard tags into the learning process.…

Machine Learning · Computer Science 2019-10-09 Seyed Amjad Seyedi , S. Siamak Ghodsi , Fardin Akhlaghian , Mahdi Jalili , Parham Moradi

Accurate multi-label classification of electrocardiogram (ECG) signals remains challenging due to the coexistence of multiple cardiac conditions, pronounced class imbalance, and long-range temporal dependencies in multi-lead recordings.…

Machine Learning · Computer Science 2026-01-28 Alireza Jafari , Fatemeh Jafari
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