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Causal structure learning refers to a process of identifying causal structures from observational data, and it can have multiple applications in biomedicine and health care. This paper provides a practical review and tutorial on scalable…

Machine Learning · Computer Science 2023-01-20 Pulakesh Upadhyaya , Kai Zhang , Can Li , Xiaoqian Jiang , Yejin Kim

A major challenge in research involving artificial intelligence (AI) is the development of algorithms that can find solutions to problems that can generalize to different environments and tasks. Unlike AI, humans are adept at finding…

Artificial Intelligence · Computer Science 2021-10-12 Semir Tatlidil , Yanqi Liu , Emily Sheetz , R. Iris Bahar , Steven Sloman

The domain gap caused mainly by variable medical image quality renders a major obstacle on the path between training a segmentation model in the lab and applying the trained model to unseen clinical data. To address this issue, domain…

Image and Video Processing · Electrical Eng. & Systems 2022-09-27 Shishuai Hu , Zehui Liao , Jianpeng Zhang , Yong Xia

Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

Causal generative modeling is essential for developing reliable and transparent AI systems capable of counterfactual reasoning. While existing approaches focus on integrating causal constraints during the training of generative models, they…

Machine Learning · Computer Science 2026-05-25 Aneesh Komanduri , Xintao Wu

A trained neural network can be interpreted as a structural causal model (SCM) that provides the effect of changing input variables on the model's output. However, if training data contains both causal and correlational relationships, a…

Machine Learning · Computer Science 2022-06-30 Sai Srinivas Kancheti , Abbavaram Gowtham Reddy , Vineeth N Balasubramanian , Amit Sharma

Language models are traditionally designed around causal masking. In domains with spatial or relational structure, causal masking is often viewed as inappropriate, and sequential linearizations are instead used. Yet the question of whether…

Artificial Intelligence · Computer Science 2025-11-03 Jared Junkin , Samuel Nathanson

Over the last few decades, psychologists have developed sophisticated formal models of human categorization using simple artificial stimuli. In this paper, we use modern machine learning methods to extend this work into the realm of…

Computer Vision and Pattern Recognition · Computer Science 2017-11-15 Ruairidh M. Battleday , Joshua C. Peterson , Thomas L. Griffiths

The aim in many sciences is to understand the mechanisms that underlie the observed distribution of variables, starting from a set of initial hypotheses. Causal discovery allows us to infer mechanisms as sets of cause and effect…

Machine Learning · Computer Science 2025-03-05 Ashka Shah , Adela DePavia , Nathaniel Hudson , Ian Foster , Rick Stevens

The availability of extensive datasets containing gaze information for each subject has significantly enhanced gaze estimation accuracy. However, the discrepancy between domains severely affects a model's performance explicitly trained for…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Younghan Kim , Kangryun Moon , Yongjun Park , Yonggyu Kim

Three distinct phenomena complicate statistical causal analysis: latent common causes, causal cycles, and latent selection. Foundational works on Structural Causal Models (SCMs), e.g., Bongers et al. (2021, Ann. Stat., 49(5): 2885-2915),…

Methodology · Statistics 2025-11-23 Leihao Chen , Onno Zoeter , Joris M. Mooij

Humans abstract experiences into structured representations to facilitate pattern inference and knowledge transfer. While the hippocampal-entorhinal (HPC-MEC) circuit is known to represent both spatial and conceptual spaces, the mechanisms…

Neural and Evolutionary Computing · Computer Science 2026-05-18 Tianqiu Zhang , Muyang Lyu , Xiao Liu , Si Wu

Medical imaging models frequently fail when deployed across hospitals, scanners, populations, or imaging protocols due to domain shift, limiting their clinical reliability. While transfer learning and domain adaptation address such shifts…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Mohammed M. Abdelsamea , Daniel Tweneboah Anyimadu , Tasneem Selim , Saif Alzubi , Lei Zhang , Ahmed Karam Eldaly , Xujiong Ye

Dynamical systems are widely used in science and engineering to model systems consisting of several interacting components. Often, they can be given a causal interpretation in the sense that they not only model the evolution of the states…

Artificial Intelligence · Computer Science 2022-03-29 Stephan Bongers , Tineke Blom , Joris M. Mooij

Although deep learning models have been successfully applied to a variety of tasks, due to the millions of parameters, they are becoming increasingly opaque and complex. In order to establish trust for their widespread commercial use, it is…

Machine Learning · Computer Science 2018-11-13 Tanmayee Narendra , Anush Sankaran , Deepak Vijaykeerthy , Senthil Mani

World modelling, i.e. building a representation of the rules that govern the world so as to predict its evolution, is an essential ability for any agent interacting with the physical world. Despite their impressive performance, many…

Machine Learning · Computer Science 2025-05-06 Francesco Petri , Luigi Asprino , Aldo Gangemi

Extracting abstract causal structures and applying them to novel situations is a hallmark of human intelligence. While Large Language Models (LLMs) and Vision Language Models (VLMs) have shown strong performance on a wide range of reasoning…

Artificial Intelligence · Computer Science 2026-04-28 Liangru Xiang , Yuxi Ma , Zhihao Cao , Yixin Zhu , Song-Chun Zhu

Deep neural networks can obtain impressive performance on various tasks under the assumption that their training domain is identical to their target domain. Performance can drop dramatically when this assumption does not hold. One…

Machine Learning · Computer Science 2024-10-10 Gaël Gendron , Michael Witbrock , Gillian Dobbie

Human beings learn causal models and constantly use them to transfer knowledge between similar environments. We use this intuition to design a transfer-learning framework using object-oriented representations to learn the causal…

Machine Learning · Computer Science 2020-07-21 Purva Pruthi , Javier González , Xiaoyu Lu , Madalina Fiterau

The paper proposes a semantic clustering based deduction learning by mimicking the learning and thinking process of human brains. Human beings can make judgments based on experience and cognition, and as a result, no one would recognize an…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Wenchi Ma , Xuemin Tu , Bo Luo , Guanghui Wang