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Traditional image annotation tasks rely heavily on human effort for object selection and label assignment, making the process time-consuming and prone to decreased efficiency as annotators experience fatigue after extensive work. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 He Zhang , Xinyi Fu , John M. Carroll

Background: More than half (57%) of pharma clinical research spend is in support of clinical trials. One reason is that Electronic Health Record (EHR) systems and HIPAA privacy rules often limit how broadly patient information can be…

Quantitative Methods · Quantitative Biology 2018-07-03 Andrew J McMurry , Richen Zhang , Alex Foxman , Lawrence Reiter , Ronny Schnel , DeLeys Brandman

Electronic Health Records (EHRs) have become the primary form of medical data-keeping across the United States. Federal law restricts the sharing of any EHR data that contains protected health information (PHI). De-identification, the…

Computation and Language · Computer Science 2021-03-26 Abdullah Ahmed , Adeel Abbasi , Carsten Eickhoff

Although large language models (LLMs) have shown exceptional capabilities across a wide range of tasks, reliable evaluation remains a critical challenge due to data contamination, opaque operation, and subjective preferences. To address…

Artificial Intelligence · Computer Science 2026-04-15 Qianhong Guo , Wei Xie , Xiaofang Cai , Enze Wang , Shuoyoucheng Ma , Xiaobing Sun , Tian Xia , Kai Chen , Xiaofeng Wang , Baosheng Wang

The efficacy of large language models (LLMs) on downstream tasks usually hinges on instruction tuning, which relies critically on the quality of training data. Unfortunately, collecting high-quality and diverse data is both expensive and…

Computation and Language · Computer Science 2024-11-25 Hang Zhou , Yehui Tang , Haochen Qin , Yujie Yang , Renren Jin , Deyi Xiong , Kai Han , Yunhe Wang

Protecting patient privacy in clinical narratives is essential for enabling secondary use of healthcare data under regulations such as GDPR and HIPAA. While manual de-identification remains the gold standard, it is costly and slow,…

Cryptography and Security · Computer Science 2026-04-24 Michele Miranda , Xinlan Yan , Nishant Mishra , Rachel Murphy , Ameen Abu-Hanna , Sébastien Bratières , Iacer Calixto

Purpose: The purpose of this study was to determine if an ensemble of multiple LLM agents could be used collectively to provide a more reliable assessment of a pixel-based AI triage tool than a single LLM. Methods: 29,766 non-contrast CT…

Computation and Language · Computer Science 2025-10-31 Adam E. Flanders , Yifan Peng , Luciano Prevedello , Robyn Ball , Errol Colak , Prahlad Menon , George Shih , Hui-Ming Lin , Paras Lakhani

Large language models (LLMs) have demonstrated remarkable capabilities across a range of text-generation tasks. However, LLMs still struggle with problems requiring multi-step decision-making and environmental feedback, such as online…

Artificial Intelligence · Computer Science 2025-02-18 Zhenfang Chen , Delin Chen , Rui Sun , Wenjun Liu , Chuang Gan

High-dimensional data remains a pervasive challenge in machine learning, often undermining model interpretability and computational efficiency. While Large Language Models (LLMs) have shown promise for dimensionality reduction through…

Machine Learning · Computer Science 2025-10-08 Mohamed Bal-Ghaoui , Fayssal Sabri

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Large Language Models (LLMs) are advancing rapidly, yet the benchmarks used to measure this progress are becoming increasingly unreliable. Score inflation and selective reporting have eroded the authority of standard benchmarks, leaving the…

Artificial Intelligence · Computer Science 2026-02-13 Longyuan Zhu , Hairan Hua , Linlin Miao , Bing Zhao

We introduce a novel large language model (LLM)-driven agent framework, which iteratively refines queries and filters contextual evidence by leveraging dynamically evolving knowledge. A defining feature of the system is its decoupling of…

Artificial Intelligence · Computer Science 2025-04-02 Seyoung Song

Topic modeling has become a crucial method for analyzing text data, particularly for extracting meaningful insights from large collections of documents. However, the output of these models typically consists of lists of keywords that…

Information Retrieval · Computer Science 2025-02-27 Trishia Khandelwal

Large Language Models (LLMs) have enabled the emergence of autonomous agents capable of complex reasoning, planning, and interaction. However, coordinating such agents at scale remains a fundamental challenge, particularly in decentralized…

Multiagent Systems · Computer Science 2025-09-23 Minfeng Qi , Tianqing Zhu , Lefeng Zhang , Ningran Li , Wanlei Zhou

Despite the utility of Large Language Models (LLMs) across a wide range of tasks and scenarios, developing a method for reliably evaluating LLMs across varied contexts continues to be challenging. Modern evaluation approaches often use LLMs…

Computation and Language · Computer Science 2024-01-31 Steffi Chern , Ethan Chern , Graham Neubig , Pengfei Liu

With the rapid expansion of unstructured clinical texts in electronic health records (EHRs), clinical named entity recognition (NER) has become a crucial technique for extracting medical information. However, traditional supervised models…

Computation and Language · Computer Science 2026-03-31 Xinli Tao , Xin Dong , Xuezhong Zhou

The rapid adoption of Large Language Models (LLMs) in interactive systems has enabled the creation of dynamic, open-ended Role-Playing Agents (RPAs). However, evaluating these agents remains a significant challenge, as standard NLP metrics…

Computation and Language · Computer Science 2026-04-14 Riccardo Rosati , Edoardo Colucci , Massimiliano Bolognini , Adriano Mancini , Paolo Sernani

One paradigm of language model (LM) fine-tuning relies on creating large training datasets, under the assumption that high quantity and diversity will enable models to generalize to novel tasks after post-training. In practice, gathering…

Machine Learning · Computer Science 2025-10-10 Emre Can Acikgoz , Cheng Qian , Heng Ji , Dilek Hakkani-Tür , Gokhan Tur

Effective model and hyperparameter selection remains a major challenge in deep learning, often requiring extensive expertise and computation. While AutoML and large language models (LLMs) promise automation, current LLM-based approaches…

Machine Learning · Computer Science 2025-10-08 Mohamed Bal-Ghaoui , Mohammed Tiouti

The advancement of Large Language Models (LLMs) enables flexible and interpretable automatic evaluations. In the field of machine translation evaluation, utilizing LLMs with translation error annotations based on Multidimensional Quality…

Computation and Language · Computer Science 2025-09-17 Shijie Zhang , Renhao Li , Songsheng Wang , Philipp Koehn , Min Yang , Derek F. Wong