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Related papers: Reliability of Large Language Model Generated Clin…

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Large Language Models (LLMs) have demonstrated potential in predicting mental health outcomes from online text, yet traditional classification methods often lack interpretability and robustness. This study evaluates structured reasoning…

Computation and Language · Computer Science 2026-01-09 Avinash Patil , Amardeep Kour Gedhu

Objective: To improve the efficiency of medical question answering (MedQA) with large language models (LLMs) by avoiding unnecessary reasoning while maintaining accuracy. Methods: We propose Selective Chain-of-Thought (Selective CoT), an…

Computation and Language · Computer Science 2026-02-24 Zaifu Zhan , Min Zeng , Shuang Zhou , Yiran Song , Xiaoyi Chen , Yu Hou , Yifan Wu , Yang Ruan , Rui Zhang

As Large Language Models (LLMs) are increasingly being employed in real-world applications in critical domains such as healthcare, it is important to ensure that the Chain-of-Thought (CoT) reasoning generated by these models faithfully…

Computation and Language · Computer Science 2024-07-02 Sree Harsha Tanneru , Dan Ley , Chirag Agarwal , Himabindu Lakkaraju

Large Language Models (LLMs) are typically trained to reflect a relatively uniform set of values, which limits their applicability to tasks that require understanding of nuanced human perspectives. Recent research has underscored the…

Computation and Language · Computer Science 2025-10-07 Yunfan Zhang , Kathleen McKeown , Smaranda Muresan

The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic…

Computation and Language · Computer Science 2024-03-15 Erlend Frayling , Jake Lever , Graham McDonald

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding, reasoning, and problem-solving across various domains. However, their ability to perform complex, multi-step reasoning task-essential…

Pretrained large language models (LLMs) are widely used in many sub-fields of natural language processing (NLP) and generally known as excellent few-shot learners with task-specific exemplars. Notably, chain of thought (CoT) prompting, a…

Computation and Language · Computer Science 2023-01-31 Takeshi Kojima , Shixiang Shane Gu , Machel Reid , Yutaka Matsuo , Yusuke Iwasawa

In task-oriented conversational AI evaluation, unsupervised methods poorly correlate with human judgments, and supervised approaches lack generalization. Recent advances in large language models (LLMs) show robust zeroshot and few-shot…

Computation and Language · Computer Science 2024-06-26 Jinghan Jia , Abi Komma , Timothy Leffel , Xujun Peng , Ajay Nagesh , Tamer Soliman , Aram Galstyan , Anoop Kumar

Large language models (LLMs) are increasingly being applied to clinical care, a domain where both accuracy and transparent reasoning are critical for safe and trustworthy deployment. Chain-of-thought (CoT) prompting, which elicits…

Computation and Language · Computer Science 2025-12-09 Jiageng Wu , Kevin Xie , Bowen Gu , Nils Krüger , Kueiyu Joshua Lin , Jie Yang

Large language models (LLMs) are increasingly adopted in clinical decision support, yet aligning them with the multifaceted reasoning pathways of real-world medicine remains a major challenge. Using more than 8,000 infertility treatment…

Machine Learning · Computer Science 2025-11-25 Dou Liu , Ying Long , Sophia Zuoqiu , Kaipeng Xie , Runze Yang , Di Liu , Kang Li , Yiting Lin , Hanyi Liu , Rong Yin , Tian Tang

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Large Language Models (LLMs) have demonstrated remarkable performance across diverse tasks and exhibited impressive reasoning abilities by applying zero-shot Chain-of-Thought (CoT) prompting. However, due to the evolving nature of sentence…

Computation and Language · Computer Science 2024-02-09 Feihu Jin , Yifan Liu , Ying Tan

Large language models (LLMs) achieve strong performance on code generation, but the mechanisms by which Chain-of-Thought (CoT) prompting helps remain unclear. We present a systematic empirical and information-theoretic study of CoT…

Software Engineering · Computer Science 2025-12-11 Naizhu Jin , Zhong Li , Guang Yang , Tian Zhang , Qingkai Zeng

Agentic retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical decision support. These systems iteratively retrieve curated domain knowledge and…

Improving performance on complex tasks and enabling interpretable decision making in large language models (LLMs), especially for clinical applications, requires effective reasoning. Yet this remains challenging without supervised…

Computation and Language · Computer Science 2025-05-26 Che Liu , Haozhe Wang , Jiazhen Pan , Zhongwei Wan , Yong Dai , Fangzhen Lin , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

Closed-source large language models (LLMs), such as ChatGPT and Gemini, are increasingly consulted for medical advice, yet their explanations may appear plausible while failing to reflect the model's underlying reasoning process. This gap…

The development of Long-CoT reasoning has advanced LLM performance across various tasks, including language understanding, complex problem solving, and code generation. This paradigm enables models to generate intermediate reasoning steps,…

Computation and Language · Computer Science 2025-09-05 Yanbo Wang , Yongcan Yu , Jian Liang , Ran He

Large Language Models (LLMs) often exhibit strong linguistic abilities while remaining unreliable on multi-step reasoning tasks, particularly when deployed without additional training or fine-tuning. In this work, we study inference-time…

Computation and Language · Computer Science 2026-03-24 Vinay Sharma , Manish Jain

Recent advances have enabled Large Language Models (LLMs) to tackle reasoning tasks by generating chain-of-thought (CoT) rationales, yet these gains have largely applied to high-resource languages, leaving low-resource languages behind. In…

Computation and Language · Computer Science 2025-11-27 Khanh-Tung Tran , Barry O'Sullivan , Hoang D. Nguyen
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