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The discovery of Metal-Organic Frameworks (MOFs) with application-specific properties remains a central challenge in materials chemistry, owing to the immense size and complexity of their structural design space. Conventional computational…

Machine Learning · Computer Science 2025-06-03 Srivathsan Badrinarayanan , Rishikesh Magar , Akshay Antony , Radheesh Sharma Meda , Amir Barati Farimani

Human motion generation, a cornerstone technique in animation and video production, has widespread applications in various tasks like text-to-motion and music-to-dance. Previous works focus on developing specialist models tailored for each…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Mingyuan Zhang , Daisheng Jin , Chenyang Gu , Fangzhou Hong , Zhongang Cai , Jingfang Huang , Chongzhi Zhang , Xinying Guo , Lei Yang , Ying He , Ziwei Liu

Analysis of molecular scale interactions and chemical structure offers an enormous opportunity to tune material properties for targeted applications. However, designing materials from molecular scale is a grand challenge owing to the…

Materials Science · Physics 2021-11-19 Praneeth S Ramesh , Tarak K Patra

A machine learning approach is presented to accelerate the computation of block polymer morphology evolution for large domains over long timescales. The strategy exploits the separation of characteristic times between coarse-grained…

Chemical Physics · Physics 2023-09-01 Hyun Park , Boyuan Yu , Juhae Park , Ge Sun , Emad Tajkhorshid , Juan J. de Pablo , Ludwig Schneider

Molecular dynamics (MD) simulations enable the description of ma- terial properties and processes with atomistic detail by numerically solv- ing the time evolution of every atom in the system. We introduce Poly- merModeler, a…

Materials Science · Physics 2015-03-16 Benjamin P. Haley , Chunyu Li , Nathaniel Wilson , Eugenio Jaramillo , Alejandro Strachan

Peptide self-assembly prediction offers a powerful bottom-up strategy for designing biocompatible, low-toxicity materials for large-scale synthesis in a broad range of biomedical and energy applications. However, screening the vast sequence…

Biomolecules · Quantitative Biology 2026-04-23 Nuno Costa , Julija Zavadlav

Foundation models or pre-trained models have substantially improved the performance of various language, vision, and vision-language understanding tasks. However, existing foundation models can only perform the best in one type of tasks,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Xinsong Zhang , Yan Zeng , Jipeng Zhang , Hang Li

High-fidelity Monte Carlo simulations and complex inverse problems, such as mapping smeared experimental observations to ground-truth states, are computationally intensive yet essential for robust data analysis. Conditional Flow Matching…

Machine Learning · Computer Science 2026-04-03 Zeyu Xia , Tyler Kim , Trevor Reed , Judy Fox , Geoffrey Fox , Adam Szczepaniak

Recent advancements in multimodal foundation models have yielded significant progress in vision-language understanding. Initial attempts have also explored the potential of multimodal large language models (MLLMs) for visual content…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Rongyao Fang , Chengqi Duan , Kun Wang , Hao Li , Hao Tian , Xingyu Zeng , Rui Zhao , Jifeng Dai , Hongsheng Li , Xihui Liu

This paper introduces Multi-Garment Customized Model Generation, a unified framework based on Latent Diffusion Models (LDMs) aimed at addressing the unexplored task of synthesizing images with free combinations of multiple pieces of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Yichen Liu , Penghui Du , Yi Liu Quanwei Zhang

Metamaterials are artificial materials that are designed to meet unseen properties in nature, such as ultra-stiffness and negative materials indices. In mechanical metamaterial design, three key modalities are typically involved, i.e., 3D…

Machine Learning · Computer Science 2025-06-23 Wangzhi Zhan , Jianpeng Chen , Dongqi Fu , Dawei Zhou

This work presents a novel framework governing the development of an efficient, accurate, and transferable coarse-grained (CG) model of a polyether material. The proposed framework combines the two fundamentally different classical…

A novel framework has recently been proposed for designing the molecular structure of chemical compounds with a desired chemical property using both artificial neural networks and mixed integer linear programming. In this paper, we design a…

Traditional AI methods often rely on task-specific model designs and training, which constrain both the scalability of model size and generalization across different tasks. Here, we introduce ChemFM, a large foundation model specifically…

Computational Engineering, Finance, and Science · Computer Science 2025-11-06 Feiyang Cai , Katelin Zacour , Tianyu Zhu , Tzuen-Rong Tzeng , Yongping Duan , Ling Liu , Srikanth Pilla , Gang Li , Feng Luo

Polymer property performance prediction aims to forecast specific features or attributes of polymers, which has become an efficient approach to measuring their performance. However, existing machine learning models face challenges in…

Machine Learning · Computer Science 2024-09-25 Xuanming Hu , Dongjie Wang , Wangyang Ying , Yanjie Fu

Designing de-novo molecules with desired property profiles requires efficient exploration of the vast chemical space ranging from $10^{23}$ to $10^{60}$ possible synthesizable candidates. While various deep generative models have been…

Machine Learning · Computer Science 2025-08-25 Kamran Chitsaz , Roshan Balaji , Quentin Fournier , Nirav Pravinbhai Bhatt , Sarath Chandar

Generative models such as AlphaFold and MatterGen can directly generate novel material structures with desired properties, accelerating the new materials discovery and revolutionizing the material design paradigm from traditional…

Granular flows govern many natural and industrial processes, yet their interior kinematics and mechanics remain largely unobservable, as experiments access only boundaries or free surfaces. Conventional numerical simulations are…

Computational Engineering, Finance, and Science · Computer Science 2026-05-26 Xuyang Li , Rui Li , Teng Man , Yimin Lu

The Earth's weather system encompasses intricate weather data modalities and diverse weather understanding tasks, which hold significant value to human life. Existing data-driven models focus on single weather understanding tasks (e.g.,…

Polymer materials have the characteristic feature that they are multiscale systems by definition. Already the description of a single molecules involves a multitude of different scales, and cooperative processes in polymer assemblies are…

Chemical Physics · Physics 2022-12-20 Friederike Schmid