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The complex nature of disease mechanisms and the variability of patient symptoms pose significant challenges in developing effective diagnostic tools. Although machine learning (ML) has made substantial advances in medical diagnosis, the…

A recent trend in machine learning has been to enrich learned models with the ability to explain their own predictions. The emerging field of Explainable AI (XAI) has so far mainly focused on supervised learning, in particular, deep neural…

Machine Learning · Computer Science 2022-07-13 Jacob Kauffmann , Malte Esders , Lukas Ruff , Grégoire Montavon , Wojciech Samek , Klaus-Robert Müller

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Artificial intelligence (AI) is becoming increasingly complex, making it difficult for users to understand how the AI has derived its prediction. Using explainable AI (XAI)-methods, researchers aim to explain AI decisions to users. So far,…

Human-Computer Interaction · Computer Science 2022-10-06 Lara Riefle , Patrick Hemmer , Carina Benz , Michael Vössing , Jannik Pries

Mental health constitutes a complex and pervasive global challenge, affecting millions of lives and often leading to severe consequences. In this paper, we conduct a thorough survey to explore the intersection of data science, artificial…

Machine Learning · Computer Science 2026-04-28 Yusif Ibrahimov , Tarique Anwar , Tommy Yuan

Explainable Artificial Intelligence (XAI) has experienced a significant growth over the last few years. This is due to the widespread application of machine learning, particularly deep learning, that has led to the development of highly…

Artificial Intelligence · Computer Science 2020-10-13 Giulia Vilone , Luca Longo

Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques…

Machine Learning · Computer Science 2022-09-15 Flavio Di Martino , Franca Delmastro

Research into explainable artificial intelligence (XAI) for data analysis tasks suffer from a large number of contradictions and lack of concrete design recommendations stemming from gaps in understanding the tasks that require AI…

Artificial Intelligence · Computer Science 2025-07-15 Hamzah Ziadeh , Hendrik Knoche

The growing adoption of artificial intelligence in healthcare has raised concerns about the transparency and trustworthiness of AI-driven medical diagnosis systems. Many existing models operate as black boxes, limiting clinicians' ability…

Human-Computer Interaction · Computer Science 2026-04-21 Altynbek Seitenov , Ainur Nurzhanova , Azhar Bekbussinova , Yerassyl Bolatkan

The adoption of intelligent systems creates opportunities as well as challenges for medical work. On the positive side, intelligent systems have the potential to compute complex data from patients and generate automated diagnosis…

Human-Computer Interaction · Computer Science 2019-02-19 Yao Xie , Ge Gao , Xiang 'Anthony' Chen

Given the complexity and lack of transparency in deep neural networks (DNNs), extensive efforts have been made to make these systems more interpretable or explain their behaviors in accessible terms. Unlike most reviews, which focus on…

Artificial Intelligence · Computer Science 2024-01-17 Haoyi Xiong , Xuhong Li , Xiaofei Zhang , Jiamin Chen , Xinhao Sun , Yuchen Li , Zeyi Sun , Mengnan Du

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

This paper presents a novel approach to Explainable AI (XAI) that combines contrastive explanations with differential privacy for clustering algorithms. Focusing on k-median and k-means problems, we calculate contrastive explanations as the…

Machine Learning · Computer Science 2025-06-03 Dung Nguyen , Ariel Vetzler , Sarit Kraus , Anil Vullikanti

Explainable AI (XAI) is widely viewed as a sine qua non for ever-expanding AI research. A better understanding of the needs of XAI users, as well as human-centered evaluations of explainable models are both a necessity and a challenge. In…

Artificial Intelligence · Computer Science 2024-10-17 Yao Rong , Tobias Leemann , Thai-trang Nguyen , Lisa Fiedler , Peizhu Qian , Vaibhav Unhelkar , Tina Seidel , Gjergji Kasneci , Enkelejda Kasneci

While the emerging research field of explainable artificial intelligence (XAI) claims to address the lack of explainability in high-performance machine learning models, in practice, XAI targets developers rather than actual end-users.…

Artificial Intelligence · Computer Science 2023-04-19 Lukas-Valentin Herm

XAI refers to the techniques and methods for building AI applications which assist end users to interpret output and predictions of AI models. Black box AI applications in high-stakes decision-making situations, such as medical domain have…

In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and…

Human-Computer Interaction · Computer Science 2026-05-06 Julia Wagner , Tim Schlippe

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Explainable AI (XAI) techniques are necessary to help clinicians make sense of AI predictions and integrate predictions into their decision-making workflow. In this work, we conduct a survey study to understand clinician preference among…

Computation and Language · Computer Science 2025-08-28 Jun Hou , Lucy Lu Wang

With the increasing availability of structured and unstructured data and the swift progress of analytical techniques, Artificial Intelligence (AI) is bringing a revolution to the healthcare industry. With the increasingly indispensable role…

Machine Learning · Computer Science 2020-11-09 Devam Dave , Het Naik , Smiti Singhal , Pankesh Patel
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