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- New advance technologies based on reverse engineering , design and additive manufacturing, have expanded design capabilities for biomedical applications to include Patient Specific Implants (PSI). This change in design paradigms needs…

Medical Physics · Physics 2017-09-21 J. Díaz , Octavio Andrés González-Estrada , C. López

Architectural simulators hold a vital role in RISC-V research, providing a crucial platform for workload evaluation without the need for costly physical prototypes. They serve as a dynamic environment for exploring innovative architectural…

Hardware Architecture · Computer Science 2024-05-27 Debjyoti Bhattacharjee , Anmol , Tommaso Marinelli , Karan Pathak , Peter Kourzanov

Modern applications process massive data volumes that overwhelm the storage and retrieval capabilities of memory systems, making memory the primary performance and energy-efficiency bottleneck of computing systems. Although many…

Hardware Architecture · Computer Science 2026-03-10 Rahul Bera

Computer models are widely used across a range of scientific disciplines to describe various complex physical systems, however to perform full uncertainty quantification we often need to employ emulators. An emulator is a fast statistical…

Methodology · Statistics 2022-10-20 Ian Vernon , Jonathan Owen , Jonathan Carter

Spinodal metamaterials, with architectures inspired by natural phase-separation processes, have presented a significant alternative to periodic and symmetric morphologies when designing mechanical metamaterials with extreme performance.…

Computational Engineering, Finance, and Science · Computer Science 2025-01-10 Prakash Thakolkaran , Michael A. Espinal , Somayajulu Dhulipala , Siddhant Kumar , Carlos M. Portela

In the Internet of Things era, where we see many interconnected and heterogeneous mobile and fixed smart devices, distributing the intelligence from the cloud to the edge has become a necessity. Due to limited computational and…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Francesco Paissan , Alberto Ancilotto , Elisabetta Farella

In cryo-electron microscopy (EM), molecular structures are determined from large numbers of projection images of individual particles. To harness the full power of this single-molecule information, we use the Bayesian inference of EM…

Biomolecules · Quantitative Biology 2018-01-17 Pilar Cossio , David Rohr , Fabio Baruffa , Markus Rampp , Volker Lindenstruth , Gerhard Hummer

The design of structural & functional materials for specialized applications is being fueled by rapid advancements in materials synthesis, characterization, manufacturing, with sophisticated computational materials modeling frameworks that…

The rapid adaptation of data driven AI models, such as deep learning inference, training, Vision Transformers (ViTs), and other HPC applications, drives a strong need for runtime precision configurable different non linear activation…

Hardware Architecture · Computer Science 2026-02-12 Mukul Lokhande , Gopal Raut , Santosh Kumar Vishvakarma

Edge computing has been emerging as a popular scenario for model inference. However, the inference performance on edge devices (e.g., Multi-Core DSP, FGPA, etc.) suffers from inefficiency due to the lack of highly optimized inference…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-02-02 Zhang Runhua , Jiang Hongxu , Tian Fangzheng , Geng Jinkun , Li Xiaobin , Ma Yuhang , Zhu Chenhui , Dong Dong , Li Xin , Wang Haojie

To address the challenges of 3D modeling and structural simulation in industrial environment, such as the difficulty of equipment deployment, and the difficulty of balancing accuracy and real-time performance, this paper proposes an…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Bowen Zheng

This paper introduces a novel approach in neuromorphic computing, integrating heterogeneous hardware nodes into a unified, massively parallel architecture. Our system transcends traditional single-node constraints, harnessing the neural…

Hardware Architecture · Computer Science 2024-10-02 Murat Isik , Jonathan Naoukin , I. Can Dikmen

Transformers have revolutionized AI in natural language processing and computer vision, but their large computation and memory demands pose major challenges for hardware acceleration. In practice, end-to-end throughput is often limited by…

Hardware Architecture · Computer Science 2026-03-20 Qunyou Liu , Marina Zapater , David Atienza

While deep learning models have replaced hand-designed features across many domains, these models are still trained with hand-designed optimizers. In this work, we leverage the same scaling approach behind the success of deep learning to…

Using simulation to predict the mechanical behavior of heterogeneous materials has applications ranging from topology optimization to multi-scale structural analysis. However, full-fidelity simulation techniques such as Finite Element…

Machine Learning · Computer Science 2021-10-26 S. Mohammadzadeh , E. Lejeune

Spine biomechanics is at a transformation with the advent and integration of machine learning and computer vision technologies. These novel techniques facilitate the estimation of 3D body shapes, anthropometrics, and kinematics from as…

Accurate and efficient modeling of soft-tissue interactions is fundamental for advancing surgical simulation, surgical robotics, and model-based surgical automation. To achieve real-time latency, classical Finite Element Method (FEM)…

GPU design space exploration (DSE) for modern AI workloads, such as Large-Language Model (LLM) inference, is challenging because of GPUs' vast, multi-modal design spaces, high simulation costs, and complex design optimization objectives…

Hardware Architecture · Computer Science 2026-03-19 Tao Zhang , Rui Ma , Shuotao Xu , Yongqiang Xiong , Peng Cheng

Data driven approaches have the potential to make modeling complex, nonlinear physical phenomena significantly more computationally tractable. For example, computational modeling of fracture is a core challenge where machine learning…

Machine Learning · Computer Science 2025-10-01 Erfan Hamdi , Emma Lejeune

Complex-Valued Neural Networks (CVNNs) have significant advantages in handling tasks that involve complex numbers. However, existing CVNNs are unable to quantify predictive uncertainty. We propose, for the first time, dropout-based Bayesian…

Hardware Architecture · Computer Science 2026-04-23 Zehuan Zhang , Mark Chen , He Li , Wayne Luk