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Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Multimodal regression aims to predict a continuous target from heterogeneous input sources and typically relies on fusion strategies such as early or late fusion. However, existing methods lack principled tools to disentangle and quantify…

Machine Learning · Computer Science 2025-12-29 Zhaozhao Ma , Shujian Yu

For many neurological disorders, prediction of disease state is an important clinical aim. Neuroimaging provides detailed information about brain structure and function from which such predictions may be statistically derived. A multinomial…

Parkinson's Disease (PD) medication management presents unique challenges due to heterogeneous disease progression and treatment response. Neurologists must balance symptom control with optimal dopaminergic dosing based on functional…

Machine Learning · Computer Science 2025-08-15 Ricardo Diaz-Rincon , Muxuan Liang , Adolfo Ramirez-Zamora , Benjamin Shickel

Multimodal learning integrates information from different modalities to enhance model performance, yet it often suffers from modality imbalance, where dominant modalities overshadow weaker ones during joint optimization. This paper reveals…

Machine Learning · Computer Science 2025-10-17 Xiaoyu Ma , Hao Chen

This paper introduces BagStacking, a novel ensemble learning method designed to enhance the detection of Freezing of Gait (FOG) in Parkinson's Disease (PD) by using a lower-back sensor to track acceleration. Building on the principles of…

Signal Processing · Electrical Eng. & Systems 2025-02-10 Seffi Cohen , Lior Rokach

Multimodal learning (MML) aims to jointly exploit the common priors of different modalities to compensate for their inherent limitations. However, existing MML methods often optimize a uniform objective for different modalities, leading to…

Machine Learning · Computer Science 2022-11-15 Yunfeng Fan , Wenchao Xu , Haozhao Wang , Junxiao Wang , Song Guo

Parkinson's disease (PD) is one of the major public health problems in the world. It is a well-known fact that around one million people suffer from Parkinson's disease in the United States whereas the number of people suffering from…

Machine Learning · Computer Science 2016-10-27 Kamal Nayan Reddy Challa , Venkata Sasank Pagolu , Ganapati Panda , Babita Majhi

Parkinson's Disease (PD) is a slowly evolving neuro-logical disease that affects about 1% of the population above 60 years old, causing symptoms that are subtle at first, but whose intensity increases as the disease progresses. Automated…

This paper presents a novel multimodal framework to distinguish between different symptom classes of subjects in the schizophrenia spectrum and healthy controls using audio, video, and text modalities. We implemented Convolution Neural…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

Parkinson's disease (PD) is a chronic, degenerative neurological disorder. PD cannot be prevented, slowed or cured as of today but highly effective symptomatic treatments are available. We consider relevant estimands and treatment effect…

Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Evaluating neurological disorders such as Parkinson's disease (PD) is a challenging task that requires the assessment of several motor and non-motor functions. In this paper, we present an end-to-end deep learning framework to measure PD…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Amirhossein Dadashzadeh , Alan Whone , Michal Rolinski , Majid Mirmehdi

Parkinson's disease (PD) has been found to affect 1 out of every 1000 people, being more inclined towards the population above 60 years. Leveraging wearable-systems to find accurate biomarkers for diagnosis has become the need of the hour,…

Machine Learning · Computer Science 2023-04-20 Poojaa C , John Sahaya Rani Alex

To overcome the imbalanced multimodal learning problem, where models prefer the training of specific modalities, existing methods propose to control the training of uni-modal encoders from different perspectives, taking the inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yake Wei , Siwei Li , Ruoxuan Feng , Di Hu

This paper discusses the benefits of incorporating multimodal data for improving latent emotion recognition accuracy, focusing on micro-expression (ME) and physiological signals (PS). The proposed approach presents a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Liangfei Zhang , Yifei Qian , Ognjen Arandjelovic , Anthony Zhu

AI-assisted gait analysis holds promise for improving Parkinson's Disease (PD) care, but current clinical dashboards lack transparency and offer no meaningful way for clinicians to interrogate or contest AI decisions. To address this issue,…

Human-Computer Interaction · Computer Science 2025-12-11 Loc Phuc Truong Nguyen , Hung Thanh Do , Hung Truong Thanh Nguyen , Hung Cao

From the original abstract: This thesis initially aims to study the pain assessment process from a clinical-theoretical perspective while exploring and examining existing automatic approaches. Building on this foundation, the primary…

Artificial Intelligence · Computer Science 2025-05-13 Stefanos Gkikas

Recent advancements in large-scale models have showcased remarkable generalization capabilities in various tasks. However, integrating multimodal processing into these models presents a significant challenge, as it often comes with a high…

Multimedia · Computer Science 2024-07-17 Hao Sun , Yu Song , Xinyao Yu , Jiaqing Liu , Yen-Wei Chen , Lanfen Lin

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kai Han , Chongwen Lyu , Lele Ma , Chengxuan Qian , Siqi Ma , Zheng Pang , Jun Chen , Zhe Liu