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The capability of cells to form surface extensions to non-locally probe the surrounding environment plays a key role in cell migration. The existing mathematical models for migration of cell populations driven by this non-local form of…

Cell Behavior · Quantitative Biology 2025-12-24 Tommaso Lorenzi , Nadia Loy , Chiara Villa

We study the long-time behaviour of phenotype-structured models describing the evolutionary dynamics of asexual species whose phenotypic fitness landscape is characterised by multiple peaks. First we consider the case where phenotypic…

Analysis of PDEs · Mathematics 2020-10-28 Tommaso Lorenzi , Camille Pouchol

We propose and investigate general kinetic models %of Boltzmann type with transition probabilities that can describe the simultaneous change of multiple microscopic states of the interacting agents. These models can be applied to many…

Mathematical Physics · Physics 2023-02-23 Marzia Bisi , Nadia Loy

In this work, we provide an asymptotic analysis of the solutions to an elliptic integro-differential equation. This equation describes the evolutionary equilibria of a phenotypically structured population, subject to selection, mutation,…

Analysis of PDEs · Mathematics 2022-01-19 Alexis Léculier , Sepideh Mirrahimi

Phenotypically structured equations arise in population biology to describe the interaction of species with their environment that brings the nutrients. This interaction usually leads to selection of the fittest individuals. Models used in…

Analysis of PDEs · Mathematics 2015-06-18 Alexander Lorz , Benoit Perthame

Populations are heterogeneous, deviating in numerous ways. Phenotypic diversity refers to the range of traits or characteristics across a population, where for cells this could be the levels of signalling, movement and growth activity, etc.…

Cell Behavior · Quantitative Biology 2025-04-11 Tommaso Lorenzi , Kevin J Painter , Chiara Villa

We discuss several models of the dynamics of interacting populations. The models are constructed by nonlinear differential equations and have two sets of parameters: growth rates and coefficients of interaction between populations. We…

Adaptation and Self-Organizing Systems · Physics 2013-07-29 Nikolay K. Vitanov , Zlatinka I. Dimitrova

In this paper, we analyze the behavior of a multi-agent system driven by the interactions of agents within a competitive environment. To achieve this, we describe the transition probabilities that underlie the system's stochastic nature. We…

Multiagent Systems · Computer Science 2024-12-23 Mohammad Daneshvar , Mandana Delavari

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

Populations and Evolution · Quantitative Biology 2020-10-14 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

We analyze the long-term stability of a stochastic model designed to illustrate the adaptation of a population to variation in its environment. A piecewise-deterministic process modeling adaptation is coupled to a Feller logistic diffusion…

Probability · Mathematics 2021-09-14 Aurélien Velleret

1) Micro-evolutionary predictions are complicated by ecological feedbacks like density dependence, while ecological predictions can be complicated by evolutionary change. A widely used approach in micro-evolution, quantitative genetics,…

Populations and Evolution · Quantitative Biology 2015-09-07 Tim Coulson , Floriane Plard , Susanne Schindler , Arpat Ozgul , Jean-Michel Gaillard

We present a systematic review of some basic results on the derivation of classical epidemiological models from simple agent-based dynamics. The evolution of large populations is coupled with the dynamics of the contact distribution,…

Populations and Evolution · Quantitative Biology 2024-10-14 Mattia Zanella

We develop a continuous mathematical model of population dynamics that describes the sequential emergence of new genotypes under limited resources. The framework models genotype density as a nonlinear flow in mutation space, combining…

Populations and Evolution · Quantitative Biology 2025-12-10 Alexander Bratus , Tatiana Yakushkina , Vladimir Posvyanski

Inferring the driving equations of a dynamical system from population or time-course data is important in several scientific fields such as biochemistry, epidemiology, financial mathematics and many others. Despite the existence of…

Machine Learning · Computer Science 2020-12-10 Anastasios Tsourtis , Yannis Pantazis , Ioannis Tsamardinos

We propose a kinetic model to describe the dynamical evolution of wealth and knowledge in national and global markets, starting from a microscopic description of individual interactions. The model is built upon interaction rules that…

Physics and Society · Physics 2026-02-24 Marzia Bisi , Martina Conte , Maria Groppi

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

Populations and Evolution · Quantitative Biology 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

Mathematical models of biological populations commonly use discrete structure classes to capture trait variation among individuals (e.g. age, size, phenotype, intracellular state). Upscaling these discrete models into continuum descriptions…

Populations and Evolution · Quantitative Biology 2026-03-18 Eleonora Agostinelli , Keith L. Chambers , Helen M. Byrne , Mohit P. Dalwadi

The aim of this paper is to study the derivation of appropriate meso- and macroscopic models for interactions as appearing in social processes. There are two main characteristics the models take into account, namely a network structure of…

Analysis of PDEs · Mathematics 2020-06-30 Martin Burger

In this paper we study a novel Fokker-Planck-type model that is designed to mimic manufacturing processes through the dynamics characterizing a large set of agents. In particular, we describe a many-agent system interacting with a target…

Adaptation and Self-Organizing Systems · Physics 2022-12-08 Ferdinando Auricchio , Giuseppe Toscani , Mattia Zanella
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