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Online Surgical Phase Recognition (SPR) models can reach high frame-wise accuracy, yet their predictions often lack temporal stability, fragmenting workflow understanding and reducing the reliability of downstream assistance. We show that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Yang Liu , Ning Zhu , Jingjing Peng , Xiwu Chen , Alejandro Granados , Guotai Wang , Sebastien Ourselin

PET is a functional imaging method that visualizes metabolic processes. TOF information can be derived from coincident detector signals and incorporated into image reconstruction to enhance the SNR. PET detectors are typically assessed by…

Instrumentation and Detectors · Physics 2025-04-24 Stephan Naunheim , Luis Lopes de Paiva , Vanessa Nadig , Yannick Kuhl , Stefan Gundacker , Florian Mueller , Volkmar Schulz

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

Biomarker analysis of athletes' urinary steroid profiles is crucial for the success of anti-doping efforts. Current statistical analysis methods generate personalised limits for each athlete based on univariate modelling of longitudinal…

Applications · Statistics 2023-10-24 Dimitra Eleftheriou , Thomas Piper , Mario Thevis , Tereza Neocleous

Detection of occult hemorrhage (i.e., internal bleeding) in patients in intensive care units (ICUs) can pose significant challenges for critical care workers. Because blood loss may not always be clinically apparent, clinicians rely on…

Cost-effectiveness analyses (CEAs) compare the costs and health outcomes of treatment regimes to inform medical decisions. With observational claims data, CEAs must address nonrandom treatment assignment, administrative censoring, and…

Methodology · Statistics 2026-01-22 Esteban Fernández-Morales , Emily M. Ko , Nandita Mitra , Youjin Lee , Arman Oganisian

Recurrent events often serve as key endpoints in clinical studies but may be prematurely truncated by terminal events such as death, creating selection bias and complicating causal inference. To address this challenge, we develop a Bayesian…

Methodology · Statistics 2026-03-18 Yuki Ohnishi , Michael O. Harhay , Guangyu Tong , Fan Li

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

Machine Learning · Computer Science 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

Cluster randomized trials (CRTs) offer a practical alternative for addressing logistical challenges and ensuring feasibility in community health, education, and prevention studies, even though randomized controlled trials are considered the…

Methodology · Statistics 2025-10-30 Jooyeon Lee , M. S. , Evan Kwiatkowski , Ph. D

In developing products for rare diseases, statistical challenges arise due to the limited number of patients available for participation in drug trials and other clinical research. Bayesian adaptive clinical trial designs offer the…

Applications · Statistics 2019-09-19 Xiao Wu , Yi Xu , Bradley P. Carlin

Many studies of biomedical time series signals aim to measure the association between frequency-domain properties of time series and clinical and behavioral covariates. However, the time-varying dynamics of these associations are largely…

Methodology · Statistics 2016-10-05 Scott A. Bruce , Martica H. Hall , Daniel J. Buysse , Robert T. Krafty

Early identification of at risk students in higher education depends on predictive models that maintain accuracy across successive cohorts -- a requirement that single-cohort modeling approaches fail to meet. This study evaluates Bayesian…

Applications · Statistics 2026-04-22 Jakob Schwerter , Amer Krivosija , Tim Novak , Katja Ickstadt , Alexander Munteanu

Adaptive approaches, allowing for more flexible trial design, have been proposed for individually randomized trials to save time or reduce sample size. However, adaptive designs for cluster-randomized trials in which groups of participants…

Methodology · Statistics 2022-01-10 Junwei Shen , Shirin Golchi , Erica E. M. Moodie , David Benrimoh

Sepsis is a poorly understood and potentially life-threatening complication that can occur as a result of infection. Early detection and treatment improves patient outcomes, and as such it poses an important challenge in medicine. In this…

Electroencephalography (EEG) foundation models have shown strong potential for learning generalizable representations from large-scale neural data, yet their clinical deployment is hindered by distribution shifts across clinical settings,…

Machine Learning · Computer Science 2026-04-21 Gabriel Jason Lee , Jathurshan Pradeepkumar , Jimeng Sun

Research on transcranial magnetic stimulation (TMS) combined with encephalography feedback (EEG-TMS) has shown that the phase of the sensorimotor mu rhythm is predictive of corticospinal excitability. Thus, if the subject-specific optimal…

Neurons and Cognition · Quantitative Biology 2024-10-10 Miriam Kirchhoff , Dania Humaidan , Ulf Ziemann

Bayesian experimental design (BED) provides a principled framework for optimizing data collection by choosing experiments that are maximally informative about unknown parameters. However, existing methods cannot deal with the joint…

Machine Learning · Statistics 2026-01-30 Sara Pérez-Vieites , Sahel Iqbal , Simo Särkkä , Dominik Baumann

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Objective: Epileptic seizures are relatively common in critically-ill children admitted to the pediatric intensive care unit (PICU) and thus serve as an important target for identification and treatment. Most of these seizures have no…

Industrial simulations of turbulent flows often rely on Reynolds-averaged Navier-Stokes (RANS) turbulence models, which contain numerous closure coefficients that need to be calibrated. In this work, we address this issue by proposing a…

Fluid Dynamics · Physics 2024-06-18 Ryley McConkey , Nikhila Kalia , Eugene Yee , Fue-Sang Lien