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Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

Deep learning models show promise in digital pathology, but their opaque decision-making processes limit trust and clinical adoption. To address this challenge, we present HIPPO, an explainable AI method for analyzing weakly-supervised…

Tissues and Organs · Quantitative Biology 2025-12-10 Jakub R. Kaczmarzyk , Chanwoo Kim , Soham Gadgil , Deepika Savant , Zhen Zhao , Joel H. Saltz , Su-In Lee , Peter K. Koo

Modeling and manufacturing of personalized cranial implants are important research areas that may decrease the waiting time for patients suffering from cranial damage. The modeling of personalized implants may be partially automated by the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Marek Wodzinski , Kamil Kwarciak , Mateusz Daniol , Daria Hemmerling

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Contrastive Language-Image Pretraining (CLIP) has emerged as a novel paradigm to learn visual models from language supervision. While researchers continue to push the frontier of CLIP, reproducing these works remains challenging. This is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Yufeng Cui , Lichen Zhao , Feng Liang , Yangguang Li , Jing Shao

Foundation models are increasingly developed in computational pathology (CPath) given their promise in facilitating many downstream tasks. While recent studies have evaluated task performance across models, less is known about the structure…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Vaibhav Mishra , William Lotter

Data selection has emerged as a core issue for large-scale visual-language model pretaining (e.g., CLIP), particularly with noisy web-curated datasets. Three main data selection approaches are: (1) leveraging external non-CLIP models to aid…

Machine Learning · Computer Science 2024-12-23 Yiping Wang , Yifang Chen , Wendan Yan , Alex Fang , Wenjing Zhou , Kevin Jamieson , Simon Shaolei Du

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

Graphical model estimation from multi-omics data requires a balance between statistical estimation performance and computational scalability. We introduce a novel pseudolikelihood-based graphical model framework that reparameterizes the…

Machine Learning · Statistics 2025-09-23 Sungdong Lee , Joshua Bang , Youngrae Kim , Hyungwon Choi , Sang-Yun Oh , Joong-Ho Won

Convolutional neural networks excel in histopathological image classification, yet their pixel-level focus hampers explainability. Conversely, emerging graph convolutional networks spotlight cell-level features and medical implications.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Ziqi Yang , Zhongyu Li , Chen Liu , Xiangde Luo , Xingguang Wang , Dou Xu , Chaoqun Li , Xiaoying Qin , Meng Yang , Long Jin

In this paper, we identify an important reproducibility challenge in the image-to-set prediction literature that impedes proper comparisons among published methods, namely, researchers use different evaluation protocols to assess their…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Luis Pineda , Amaia Salvador , Michal Drozdzal , Adriana Romero

Diffusion models have achieved remarkable success in generating high-quality images thanks to their novel training procedures applied to unprecedented amounts of data. However, training a diffusion model from scratch is computationally…

Machine Learning · Computer Science 2023-03-28 Michał Zając , Kamil Deja , Anna Kuzina , Jakub M. Tomczak , Tomasz Trzciński , Florian Shkurti , Piotr Miłoś

The Consolidated Standards of Reporting Trials statement is the global benchmark for transparent and high-quality reporting of randomized controlled trials. Manual verification of CONSORT adherence is a laborious, time-intensive process…

Computation and Language · Computer Science 2025-11-18 Zhichao He , Mouxiao Bian , Jianhong Zhu , Jiayuan Chen , Yunqiu Wang , Wenxia Zhao , Tianbin Li , Bing Han , Jie Xu , Junyan Wu

Recent large language models have been trained on vast datasets, but also often on repeated data, either intentionally for the purpose of upweighting higher quality data, or unintentionally because data deduplication is not perfect and the…

Understanding the memorization and privacy leakage risks in Contrastive Language--Image Pretraining (CLIP) is critical for ensuring the security of multimodal models. Recent studies have demonstrated the feasibility of extracting sensitive…

Cryptography and Security · Computer Science 2026-05-22 Yunhao Chen , Shujie Wang , Xin Wang , Ran He , Xingjun Ma , Yu-Gang Jiang

Healthcare is one of the foremost applications of machine learning (ML). Traditionally, ML models are trained by central servers, which aggregate data from various distributed devices to forecast the results for newly generated data. This…

Machine Learning · Computer Science 2023-10-12 Sankalp Vyas , Amar Nath Patra , Raj Mani Shukla

White blood cell (WBC) classification plays a vital role in hematology for diagnosing various medical conditions. However, it faces significant challenges due to domain shifts caused by variations in sample sources (e.g., blood or bone…

Foundation models are trained on massive amounts of data to distinguish complex patterns and can be adapted to a wide range of downstream tasks with minimal computational resources. Here, we develop a foundation model for prostate cancer…

Image and Video Processing · Electrical Eng. & Systems 2024-11-25 Joona Pohjonen , Abderrahim-Oussama Batouche , Antti Rannikko , Kevin Sandeman , Andrew Erickson , Esa Pitkanen , Tuomas Mirtti

Medical report generation task, which targets to produce long and coherent descriptions of medical images, has attracted growing research interests recently. Different from the general image captioning tasks, medical report generation is…

Computation and Language · Computer Science 2023-04-12 Fenglin Liu , Shen Ge , Yuexian Zou , Xian Wu
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