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Positron Emission Tomography (PET) imaging is a vital tool in medical diagnostics, offering detailed insights into molecular processes within the human body. However, PET images often suffer from complicated noise, which can obscure…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Xuehua Ye , Hongxu Yang , Adam J. Schwarz

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Boxiao Yu , Kuang Gong

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…

Medical Physics · Physics 2018-08-01 Kuang Gong , Jaewon Yang , Kyungsang Kim , Georges El Fakhri , Youngho Seo , Quanzheng Li

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. However, low-count PET scans often suffer from high image noise, which can negatively impact image…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Huidong Xie , Qiong Liu , Bo Zhou , Xiongchao Chen , Xueqi Guo , Chi Liu

Working from a Poisson-Gaussian noise model, a multi-sample extension of the Photon Counting Histogram Expectation Maximization (PCH-EM) algorithm is derived as a general-purpose alternative to the Photon Transfer (PT) method. This…

Instrumentation and Detectors · Physics 2024-03-08 Aaron J. Hendrickson , David P. Haefner , Stanley H. Chan , Nicholas R. Shade , Eric R. Fossum

Low-count positron emission tomography (PET) reconstruction is a challenging inverse problem due to severe degradations arising from Poisson noise, photon scarcity, and attenuation correction errors. Existing deep learning methods typically…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zheng Zhang , Hao Tang , Yingying Hu , Zhanli Hu , Jing Qin

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

Low-resolution and signal-dependent noise distribution in positron emission tomography (PET) images makes denoising process an inevitable step prior to qualitative and quantitative image analysis tasks. Conventional PET denoising methods…

Computer Vision and Pattern Recognition · Computer Science 2014-07-14 Awais Mansoor , Ulas Bagci , Daniel J. Mollura

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Photon-limited imaging arises when the number of photons collected by a sensor array is small relative to the number of detector elements. Photon limitations are an important concern for many applications such as spectral imaging, night…

Computer Vision and Pattern Recognition · Computer Science 2014-04-29 Joseph Salmon , Zachary Harmany , Charles-Alban Deledalle , Rebecca Willett

Radiation exposure in positron emission tomography (PET) imaging limits its usage in the studies of radiation-sensitive populations, e.g., pregnant women, children, and adults that require longitudinal imaging. Reducing the PET radiotracer…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Viswanath P. Sudarshan , Uddeshya Upadhyay , Gary F. Egan , Zhaolin Chen , Suyash P. Awate

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

While Positron emission tomography (PET) imaging has been widely used in diagnosis of number of diseases, it has costly acquisition process which involves radiation exposure to patients. However, magnetic resonance imaging (MRI) is a safer…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Hajar Emami , Qiong Liu , Ming Dong

Optical Coherence Tomography (OCT) imaging is pivotal in diagnosing ophthalmic conditions by providing detailed cross-sectional images of the anterior and posterior segments of the eye. Nonetheless, speckle noise and other imaging artifacts…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Akkidas Noel Prakash , Jahnvi Sai Ganta , Ramaswami Krishnadas , Tin A. Tunc , Satish K Panda

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

Cross-dose denoising for low-dose positron emission tomography (LDPET) has been proposed to address the limited generalization of models trained at a single noise level. However, neural networks trained on a specific dose level often fail…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yichao Liu , Zongru Shao , Yueyang Teng , Junwen Guo
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