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Membrane bending is an extensively studied problem from both modeling and experimental perspectives because of the wide implications of curvature generation in cell biology. Many of the curvature generating aspects in membranes can be…

Soft Condensed Matter · Physics 2021-07-21 Arijit Mahapatra , David Saintillan , Padmini Rangamani

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn

Collective rotations are common in active matter, enhancing cohesion, transport, and mixing. They are typically attributed to chiral non-reciprocal dynamics due to intrinsic particle chirality, torque-generating interactions among units, or…

Soft Condensed Matter · Physics 2026-04-20 Maks Pečnik Bambič , Nuno A. M. Araújo , Giorgio Volpe

We investigate the dynamics of a phase-separating binary fluid, containing colloidal dumbbells anchored to the fluid-fluid interface. Extensive Lattice Boltzmann-Immersed Boundary method simulations reveal that the presence of soft…

Soft Condensed Matter · Physics 2022-01-20 A. Tiribocchi , F. Bonaccorso , M. Lauricella , S. Melchionna , A. Montessori , S. Succi

Steady structures originating from dynamic self-assembly have begun to show their advantages in new generation materials, and pose challenges to equilibrium self-assembly. In view of the important role of confinement in self-assembly, here,…

Computational Physics · Physics 2019-08-06 Rui-fen Zhang , Chun-lai Ren , Jia-wei Feng , Yu-qiang Ma

Molecular dynamics simulations are used to study capillary adhesion from a nanometer scale liquid bridge between two parallel flat solid surfaces. The capillary force and the meniscus shape of the bridge are computed as the separation…

Soft Condensed Matter · Physics 2016-08-19 Shengfeng Cheng , Mark O. Robbins

We develop an agent-based model of vasculogenesis, the de novo formation of blood vessels. Endothelial cells in the vessel network are viewed as linearly elastic spheres and are of two types: vessel elements are contained within the…

Quantitative Methods · Quantitative Biology 2016-10-04 Holger Perfahl , Barry D Hughes , Tomas Alaracon , Philip K Maini , Mark C Lloyd , Matthias Reuss , Helen M Byrne

Chemically active colloids or enzymes cluster into dense droplets driven by their phoretic response to collectively generated chemical gradients. Employing Brownian dynamics simulation techniques, our study of the dynamics of such a…

Soft Condensed Matter · Physics 2024-01-29 K. R. Prathyusha , Suropriya Saha , Ramin Golestanian

Wet granular materials in a quasi-static steady state shear flow have been studied with discrete particle simulations. Macroscopic quantities, consistent with the conservation laws of continuum theory, are obtained by time averaging and…

Soft Condensed Matter · Physics 2015-06-23 Sudeshna Roy , Abhinendra Singh , Stefan Luding , Thomas Weinhart

Chiral active matter is enjoying a rapid increase of interest, spurred by the rich variety of asymmetries that can be attained in e.g. the shape or self-propulsion mechanism of active particles. Though this has already led to the observance…

Soft Condensed Matter · Physics 2023-02-15 Vincent E. Debets , Hartmut Löwen , Liesbeth M. C. Janssen

Colloidal particles are often seen as big atoms that can be directly observed in real space. They are therefore playing an increasingly important role as model systems to study processes of interest in condensed matter physics such as…

Active flows are central to mixing and transport across living systems. While Newtonian fluids remain laminar, diffusive and predictable at the microscale, living fluids like dense bacterial suspensions can exhibit highly chaotic flows like…

Fluid Dynamics · Physics 2026-05-26 Suvarchalanjan Bellaganti , Amal Manoharan , Kirti Kashyap , Siddhartha Mukherjee

Biological membranes and vesicles play a central role in living systems, forming dynamic interfaces that regulate cellular organization and function. Classical descriptions of membrane mechanics that are rooted in equilibrium statistical…

Soft Condensed Matter · Physics 2026-02-24 Sreekanth Ramesh , Prashant K. Purohit , Yashashree Kulkarni

We study non-equilibrium analogues of surface phase transitions in a minimal model of active particles in contact with a purely repulsive potential barrier that mimics a thin porous membrane. Under conditions of bulk motility-induced phase…

Statistical Mechanics · Physics 2021-12-15 Francesco Turci , Nigel B. Wilding

Ciliated organs transport viscous fluids through confined ducts, yet how duct morphology and ciliary activity jointly set the limits of flow rate and sustainable pressure remains unclear. Here, we model dense arrays of beating cilia lining…

Fluid Dynamics · Physics 2026-05-22 JP Raimondi , Feng Ling , Eva Kanso

Membrane pores are implicated in several critical functions, including cell fusion and the transport of signaling molecules for intercellular communication. However, these structural features are often difficult to probe directly. Droplet…

Soft Condensed Matter · Physics 2025-11-13 Nivedina A. Sarma , David A. King , Xuefei Wu , Brett A. Helms , Paul D. Ashby , Thomas P. Russell , Ahmad K. Omar

Liquid drops are everywhere around us and important in numerous technological applications. Here, we demonstrate a quasi-two-dimensional (Q2D) analogy to the regular, often close to axisymmetric, three-dimensional (3D) drops. The Q2D drops…

Fluid Dynamics · Physics 2024-01-23 Tytti Kärki , Into Pääkkönen , Nikos Kyriakopoulos , Jaakko V. I. Timonen

The motion of cells in tissues is an ubiquitous phenomenon. In particular, in monolayered cell colonies in vitro, pronounced collective behavior with swirl-like motion has been observed deep within a cell colony, while at the same time, the…

Biological Physics · Physics 2024-06-03 Debarati Sarkar , Gerhard Gompper , Jens Elgeti

A theoretical model for stratified epithelium is presented. The viscoelastic properties of the tissue is assumed to be dependent on the spatial distribution of proliferative and differentiated cells. Based on this assumption, a hydrodynamic…

Biological Physics · Physics 2016-06-08 Wei-Ting Yeh , Hsuan-Yi Chen

Collective cell migration plays a central role in tissue development, morphogenesis, wound repair and cancer progression. With the growing realization that physical forces mediate cell motility in development and physiology, a key…

Biological Physics · Physics 2018-12-07 Shiladitya Banerjee , M. Cristina Marchetti
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