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Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ziyun Liang , Xiaoqing Guo , Wentian Xu , Yasin Ibrahim , Natalie Voets , Pieter M Pretorius , J. Alison Noble , Konstantinos Kamnitsas

In medical imaging, obtaining large amounts of labeled data is often a hurdle, because annotations and pathologies are scarce. Anomaly detection is a method that is capable of detecting unseen abnormal data while only being trained on…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Djennifer K. Madzia-Madzou , Hugo J. Kuijf

In medical applications, weakly supervised anomaly detection methods are of great interest, as only image-level annotations are required for training. Current anomaly detection methods mainly rely on generative adversarial networks or…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Julia Wolleb , Florentin Bieder , Robin Sandkühler , Philippe C. Cattin

The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Serban Stan , Mohammad Rostami

Early detection of newly emerging diseases, lesion severity assessment, differentiation of medical conditions and automated screening are examples for the wide applicability and importance of anomaly detection (AD) and unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Branko Mitic , Philipp Seeböck , Helmut Prosch , Georg Langs

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Early and accurate disease detection is crucial for patient management and successful treatment outcomes. However, the automatic identification of anomalies in medical images can be challenging. Conventional methods rely on large labeled…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Cosmin I Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A Schnabel

In this paper, we study unsupervised anomaly detection algorithms that learn a neural network representation, i.e. regular patterns of normal data, which anomalies are deviating from. Inspired by a similar concept in engineering, we refer…

Machine Learning · Computer Science 2025-11-12 Simon Klüttermann , Tim Katzke , Emmanuel Müller

Unsupervised Anomaly Detection (UAD) techniques aim to identify and localize anomalies without relying on annotations, only leveraging a model trained on a dataset known to be free of anomalies. Diffusion models learn to modify inputs $x$…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Sergio Naval Marimont , Matthew Baugh , Vasilis Siomos , Christos Tzelepis , Bernhard Kainz , Giacomo Tarroni

Diffusion models have shown superior performance on unsupervised anomaly detection tasks. Since trained with normal data only, diffusion models tend to reconstruct normal counterparts of test images with certain noises added. However, these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Hang Yao , Ming Liu , Haolin Wang , Zhicun Yin , Zifei Yan , Xiaopeng Hong , Wangmeng Zuo

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

Unsupervised anomaly detection methods offer a promising and flexible alternative to supervised approaches, holding the potential to revolutionize medical scan analysis and enhance diagnostic performance. In the current landscape, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Cosmin I. Bercea , Esther Puyol-Antón , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel , Andrew P. King

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

Unsupervised Continuous Anomaly Detection (UCAD) is gaining attention for effectively addressing the catastrophic forgetting and heavy computational burden issues in traditional Unsupervised Anomaly Detection (UAD). However, existing UCAD…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Mingle Zhou , Jiahui Liu , Jin Wan , Gang Li , Min Li

In anomaly detection (AD), one seeks to identify whether a test sample is abnormal, given a data set of normal samples. A recent and promising approach to AD relies on deep generative models, such as variational autoencoders (VAEs), for…

Machine Learning · Computer Science 2021-11-05 Tal Daniel , Thanard Kurutach , Aviv Tamar

Anomaly detection tools and methods present a key capability in modern cyberphysical and failure prediction systems. Despite the fast-paced development in deep learning architectures for anomaly detection, model optimization for a given…

Machine Learning · Computer Science 2023-05-29 Marcin Pietron , Dominik Zurek , Kamil Faber , Roberto Corizzo

Traditional deep learning models often lack annotated data, especially in cross-domain applications such as anomaly detection, which is critical for early disease diagnosis in medicine and defect detection in industry. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Wahyu Rahmaniar , Kenji Suzuki

Out-of-distribution (OOD) detection is crucial for enhancing the generalization of AI models used in mammogram screening. Given the challenge of limited prior knowledge about OOD samples in external datasets, unsupervised generative…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Zhemin Zhang , Bhavika Patel , Bhavik Patel , Imon Banerjee

Medical anomaly detection is a crucial yet challenging task aimed at recognizing abnormal images to assist in diagnosis. Due to the high-cost annotations of abnormal images, most methods utilize only known normal images during training and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yu Cai , Hao Chen , Xin Yang , Yu Zhou , Kwang-Ting Cheng

Anomaly detection on dynamic graphs refers to detecting entities whose behaviors obviously deviate from the norms observed within graphs and their temporal information. This field has drawn increasing attention due to its application in…

Machine Learning · Computer Science 2023-10-26 Shiqi Lou , Qingyue Zhang , Shujie Yang , Yuyang Tian , Zhaoxuan Tan , Minnan Luo
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