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Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

Unsupervised anomaly detection (UAD) learns one-class classifiers exclusively with normal (i.e., healthy) images to detect any abnormal (i.e., unhealthy) samples that do not conform to the expected normal patterns. UAD has two main…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Yu Tian , Guansong Pang , Fengbei Liu , Yuanhong chen , Seon Ho Shin , Johan W. Verjans , Rajvinder Singh , Gustavo Carneiro

Graph anomaly detection (GAD) is a critical task in graph machine learning, with the primary objective of identifying anomalous nodes that deviate significantly from the majority. This task is widely applied in various real-world scenarios,…

Machine Learning · Computer Science 2025-07-03 Xiang Li , Jianpeng Qi , Zhongying Zhao , Guanjie Zheng , Lei Cao , Junyu Dong , Yanwei Yu

Unsupervised anomaly detection (UAD) aims to find anomalous images by optimising a detector using a training set that contains only normal images. UAD approaches can be based on reconstruction methods, self-supervised approaches, and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Yu Tian , Guansong Pang , Yuyuan Liu , Chong Wang , Yuanhong Chen , Fengbei Liu , Rajvinder Singh , Johan W Verjans , Mengyu Wang , Gustavo Carneiro

The detection of lesions in magnetic resonance imaging (MRI)-scans of human brains remains challenging, time-consuming and error-prone. Recently, unsupervised anomaly detection (UAD) methods have shown promising results for this task. These…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Finn Behrendt , Marcel Bengs , Frederik Rogge , Julia Krüger , Roland Opfer , Alexander Schlaefer

T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy. However, current clinical diagnoses primarily rely on manual evaluation. Deep learning methods have shown promise…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Kun Wang , Lianming Wu , Hongxing Shen , Jianqi Sun

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Continuous electrocardiogram (ECG) monitoring via wearable devices is vital for early cardiovascular disease detection. However, deploying deep learning models on resource-constrained microcontrollers faces reliability challenges,…

Machine Learning · Computer Science 2026-01-26 Mustafa Fuad Rifet Ibrahim , Maurice Meijer , Alexander Schlaefer , Peer Stelldinger

Unlike conventional anomaly detection research that focuses on point anomalies, our goal is to detect anomalous collections of individual data points. In particular, we perform group anomaly detection (GAD) with an emphasis on irregular…

Computer Vision and Pattern Recognition · Computer Science 2018-04-16 Raghavendra Chalapathy , Edward Toth , Sanjay Chawla

Dealing with atypical traffic scenarios remains a challenging task in autonomous driving. However, most anomaly detection approaches cannot be trained on raw sensor data but require exposure to outlier data and powerful semantic…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Daniel Bogdoll , Noël Ollick , Tim Joseph , Svetlana Pavlitska , J. Marius Zöllner

Obtaining models that capture imaging markers relevant for disease progression and treatment monitoring is challenging. Models are typically based on large amounts of data with annotated examples of known markers aiming at automating…

Computer Vision and Pattern Recognition · Computer Science 2017-03-20 Thomas Schlegl , Philipp Seeböck , Sebastian M. Waldstein , Ursula Schmidt-Erfurth , Georg Langs

Unsupervised anomaly detection (UAD) plays a crucial role in neuroimaging for identifying deviations from healthy subject data and thus facilitating the diagnosis of neurological disorders. In this work, we focus on Bayesian flow networks…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Hugues Roy , Reuben Dorent , Ninon Burgos

Expert interpretation of anatomical images of the human brain is the central part of neuro-radiology. Several machine learning-based techniques have been proposed to assist in the analysis process. However, the ML models typically need to…

Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to detect outliers either in…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Changhee Han , Leonardo Rundo , Kohei Murao , Tomoyuki Noguchi , Yuki Shimahara , Zoltan Adam Milacski , Saori Koshino , Evis Sala , Hideki Nakayama , Shinichi Satoh

Unsupervised anomaly detection is a popular approach for the analysis of neuroimaging data as it allows to identify a wide variety of anomalies from unlabelled data. It relies on building a subject-specific model of healthy appearance to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Maëlys Solal , Ravi Hassanaly , Ninon Burgos

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Due to the diversity of brain anatomy and the scarcity of annotated data, supervised anomaly detection for brain MRI remains challenging, driving the development of unsupervised anomaly detection (UAD) approaches. Current UAD methods…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Hao Li , Zhenfeng Zhuang , Jingyu Lin , Yu Liu , Yifei Chen , Qiong Peng , Lequan Yu , Liansheng Wang

Diffusion magnetic resonance imaging (dMRI) is a crucial technique in neuroimaging studies, allowing for the non-invasive probing of the underlying structures of brain tissues. Clinical dMRI data is susceptible to various artifacts during…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Sheng Chen , Zihao Tang , Xinyi Wang , Chenyu Wang , Weidong Cai

Recent advances in deep learning led to novel generative modeling techniques that achieve unprecedented quality in generated samples and performance in learning complex distributions in imaging data. These new models in medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Xiaoran Chen , Nick Pawlowski , Martin Rajchl , Ben Glocker , Ender Konukoglu