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Large language models (LLMs) for code editing have achieved remarkable progress, yet recent empirical studies reveal a fundamental disconnect between technical accuracy and developer productivity. Despite their strong benchmark performance,…

Software Engineering · Computer Science 2026-04-09 Chenyan Liu , Yun Lin , Jiaxin Chang , Jiawei Liu , Binhang Qi , Bo Jiang , Zhiyong Huang , Jin Song Dong

Open-source Large Language Models (LLMs) and their specialized variants, particularly Code LLMs, have recently delivered impressive performance. However, previous Code LLMs are typically fine-tuned on single-source data with limited quality…

Computation and Language · Computer Science 2025-02-04 Zifan Song , Yudong Wang , Wenwei Zhang , Kuikun Liu , Chengqi Lyu , Demin Song , Qipeng Guo , Hang Yan , Dahua Lin , Kai Chen , Cairong Zhao

Code optimization is the process of enhancing code efficiency, while preserving its intended functionality. This process often requires a deep understanding of the code execution behavior at run-time to identify and address inefficiencies…

Software Engineering · Computer Science 2026-04-02 Federico Di Menna , Luca Traini , Gabriele Bavota , Vittorio Cortellessa

Despite recent advances in computer vision, Earth Observation (EO) analysis remains difficult to perform for the laymen, requiring expert knowledge and technical capabilities. Furthermore, many systems return black-box predictions that are…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lamia Lahouel , Laurynas Lopata , Simon Gruening , Gabriele Meoni , Gaetan Petit , Sylvain Lobry

Large Language Models (LLMs) and Vision Language Models (VLMs) have recently shown promising capabilities in various scientific domain. In particular, these advances have opened new opportunities in drug discovery, where the ability to…

Artificial Intelligence · Computer Science 2026-05-13 Jueon Park , Wonjune Jang , Jiwoo Lee , Yein Park , Jaewoo Kang

Code generation refers to automatically producing executable programs from user requirements. Recently, researchers have explored approaches to enhance the correctness of generated code with advanced large language models. Although…

Software Engineering · Computer Science 2026-04-20 Jia Li , Ruiqi Bai , Yangkang Luo , Yiran Zhang , Wentao Yang , Zeyu Sun , Tiankuo Zhao , Dongming Jin , Lei Li , Zhi Jin

Large language models (LLMs) have greatly accelerated the automation of algorithm generation and optimization. However, current methods such as EoH and FunSearch mainly rely on predefined templates and expert-specified functions that focus…

Software Engineering · Computer Science 2025-03-17 Zhe Zhao , Haibin Wen , Pengkun Wang , Ye Wei , Zaixi Zhang , Xi Lin , Fei Liu , Bo An , Hui Xiong , Yang Wang , Qingfu Zhang

The capabilities of Large Language Models (LLMs) have significantly evolved, extending from natural language processing to complex tasks like code understanding and generation. We expand the scope of LLMs' capabilities to a broader context,…

Computation and Language · Computer Science 2024-10-11 Chenyang Lyu , Lecheng Yan , Rui Xing , Wenxi Li , Younes Samih , Tianbo Ji , Longyue Wang

Molecule design is a multifaceted approach that leverages computational methods and experiments to optimize molecular properties, fast-tracking new drug discoveries, innovative material development, and more efficient chemical processes.…

Computation and Language · Computer Science 2024-08-23 Sakhinana Sagar Srinivas , Venkataramana Runkana

Human cognitive behavior arises from the interaction of specialized brain networks dedicated to distinct functions, such as language, logic, and social reasoning. Inspired by this organization, we propose Mixture of Cognitive Reasoners…

Machine Learning · Computer Science 2026-04-14 Badr AlKhamissi , C. Nicolò De Sabbata , Greta Tuckute , Zeming Chen , Martin Schrimpf , Antoine Bosselut

Molecular docking is a key computational tool utilized to predict the binding conformations of small molecules to protein targets, which is fundamental in the design of novel drugs. Despite recent advancements in geometric deep…

Biomolecules · Quantitative Biology 2023-12-01 Jiaxian Yan , Zaixi Zhang , Kai Zhang , Qi Liu

Advancements in artificial intelligence for molecular science are necessitating a paradigm shift from purely data-driven predictions to knowledge-guided computational reasoning. Existing molecular models are predominantly proprietary,…

Machine Learning · Computer Science 2026-03-16 Pengfei Liu , Shuang Ge , Jun Tao , Zhixiang Ren

Large Language Models (LLMs) are increasingly being used in education, yet their correctness alone does not capture the quality, reliability, or pedagogical validity of their problem-solving behavior, especially in mathematics, where…

Computers and Society · Computer Science 2025-10-22 Sagnik Dakshit , Sushmita Sinha Roy

Accurate molecular property prediction is a critical challenge with wide-ranging applications in chemistry, materials science, and drug discovery. Molecular representation methods, including fingerprints and graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-08-13 Jiaxin Ju , Yizhen Zheng , Huan Yee Koh , Can Wang , Shirui Pan

(Source) code summarization aims to automatically generate succinct natural language summaries for given code snippets. Such summaries play a significant role in promoting developers to understand and maintain code. Inspired by neural…

Software Engineering · Computer Science 2024-07-03 Chunrong Fang , Weisong Sun , Yuchen Chen , Xiao Chen , Zhao Wei , Quanjun Zhang , Yudu You , Bin Luo , Yang Liu , Zhenyu Chen

Large Language Models (LLMs) have shown great potential in supporting automated code review due to their impressive capabilities in context understanding and reasoning. However, these capabilities are still limited compared to human-level…

Software Engineering · Computer Science 2025-09-26 Yongda Yu , Guohao Shi , Xianwei Wu , Haochuan He , XueMing Gu , Qianqian Zhao , Kui Liu , Qiushi Wang , Zhao Tian , Haifeng Shen , Guoping Rong

Understanding molecules is key to understanding organisms and driving advances in drug discovery, requiring interdisciplinary knowledge across chemistry and biology. Although large molecular language models have achieved notable success in…

Machine Learning · Computer Science 2025-10-03 Dongki Kim , Wonbin Lee , Sung Ju Hwang

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

The combination of Large Language Models (LLMs), systematic evaluation, and evolutionary algorithms has enabled breakthroughs in combinatorial optimization and scientific discovery. We propose to extend this powerful combination to the…

Artificial Intelligence · Computer Science 2026-03-12 Carlo Bosio , Mark W. Mueller

The integration of deep learning, particularly AI-Generated Content, with high-quality data derived from ab initio calculations has emerged as a promising avenue for transforming the landscape of scientific research. However, the challenge…

Machine Learning · Computer Science 2024-12-11 Kaiwei Zhang , Yange Lin , Guangcheng Wu , Yuxiang Ren , Xuecang Zhang , Bo wang , Xiaoyu Zhang , Weitao Du