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We study a regularized interacting particle method for computing aggregation patterns and near singular solutions of a Keller-Segal (KS) chemotaxis system in two and three space dimensions, then further develop DeepParticle (DP) method to…

Computational Physics · Physics 2024-01-30 Zhongjian Wang , Jack Xin , Zhiwen Zhang

We consider the Keller-Segel model of chemotaxis on one-dimensional networks. Using a variational characterization of solutions, positivity preservation, conservation of mass, and energy estimates, we establish global existence of weak…

Numerical Analysis · Mathematics 2018-05-03 Herbert Egger , Lucas Schöbel-Kröhn

In this work, we develop a novel numerical scheme to solve the classical Keller--Segel (KS) model which simultaneously preserves its intrinsic mathematical structure and achieves optimal accuracy. The model is reformulated into a gradient…

Numerical Analysis · Mathematics 2025-09-23 X. Yin , X. Lan , Y. Qin

Auto-chemotaxis, the directed movement of cells along gradients in chemicals they secrete, is central to the formation of complex spatiotemporal patterns in biological systems. Since the introduction of the Keller--Segel model, numerous…

Soft Condensed Matter · Physics 2025-11-18 Henrik Weyer , David Muramatsu , Erwin Frey

Chemotaxis systems of Keller--Segel type constitute one of the central mathematical frameworks for understanding aggregation phenomena in biological and ecological systems. Over the past decades, the theory has evolved from the classical…

Analysis of PDEs · Mathematics 2026-03-06 Kolade M Owolabi , Eben Mare , Clara O Ijalana , Kolawole S Adegbie

We introduce stochastic models of chemotaxis generalizing the deterministic Keller-Segel model. These models include fluctuations which are important in systems with small particle numbers or close to a critical point. Following Dean's…

Statistical Mechanics · Physics 2009-09-01 Pierre-Henri Chavanis

We prove uniqueness in the class of integrable and bounded nonnegative solutions in the energy sense to the Keller-Segel (KS) chemotaxis system. Our proof works for the fully parabolic KS model, it includes the classical parabolic-elliptic…

Analysis of PDEs · Mathematics 2012-12-07 J. A. Carrillo , S. Lisini , E. Mainini

We investigate a one dimensional flux limited Keller Segel system (FLKS) in which the chemical decay rate is allowed to vary explicitly in time, a feature motivated by enzymatic regulation and environmental variability in chemotactic…

Analysis of PDEs · Mathematics 2026-05-21 Ahmed Abbas Jaber Al Furaiji , Ghorbanali Haghighatdoost , Mustafa Bazghandi

In this paper, we propose and study a stochastic aggregation-diffusion equation of the Keller-Segel (KS) type for modeling the chemotaxis in dimensions $d=2,3$. Unlike the classical deterministic KS system, which only allows for…

Analysis of PDEs · Mathematics 2020-09-23 Hui Huang , Jinniao Qiu

This paper is devoted to constructing approximate solutions for the classical Keller--Segel model governing \emph{chemotaxis}. It consists of a system of nonlinear parabolic equations, where the unknowns are the average density of cells (or…

Numerical Analysis · Mathematics 2024-02-13 Juan Vicente Gutiérrez-Santacreu , José Rafael Rodríguez-Galván

We propose a unified learning framework for identifying the profile function in discrete Keller-Segel equations, which are widely used mathematical models for understanding chemotaxis. Training data are obtained via either a rigorously…

Numerical Analysis · Mathematics 2025-10-28 Chi-An Chen , Chun Liu , Ming Zhong

Chemotaxis plays a significant role in numerous physiological processes. The Keller-Segel equation serves as a mathematical model for simulating the phenomenon of cell population aggregation under chemotaxis, possessing physical properties…

Numerical Analysis · Mathematics 2025-02-24 Mingmei Chen , Kun Wang , Cong Xie

As a class of nonlinear partial differential equations, the Keller-Segel system is widely used to model chemotaxis in biology. In this paper, we present the construction and analysis of a decoupled linear, mass-conservative, block-centered…

Numerical Analysis · Mathematics 2025-01-24 Jie Xu , Hongfei Fu

This paper considers the Keller-Segel model coupled to stochastic Navier-Stokes equations (KS-SNS, for short), which describes the dynamics of oxygen and bacteria densities evolving within a stochastically forced 2D incompressible viscous…

Analysis of PDEs · Mathematics 2024-08-02 Lei Zhang , Bin Liu

We study the Keller-Segel model of chemotaxis and develop a composite particle-grid numerical method with adaptive time stepping which allows us to accurately resolve singular solutions. The numerical findings (in two dimensions) are then…

Analysis of PDEs · Mathematics 2013-02-20 Ibrahim Fatkullin

We introduce a multi-species diffuse interface model for tumor growth, characterized by its incorporation of essential features related to chemotaxis, angiogenesis and proliferation mechanisms. We establish the weak well-posedness of the…

Analysis of PDEs · Mathematics 2023-11-23 Abramo Agosti , Andrea Signori

Lagrangian Coherent Structures (LCS) are flow features which are defined to objectively characterize complex fluid behavior over a finite time regardless of the orientation of the observer. Fluidic applications of LCS include geophysical,…

Fluid Dynamics · Physics 2023-10-18 Tanner D. Harms , Steven L. Brunton , Beverley J. McKeon

We extend the semi-Lagrangian discontinuous Galerkin (SLDG) method of Einkemmer to velocity grids with adaptive mesh refinement (AMR) and to three-dimensional velocity space. The original SLDG formulation assumes uniform cell widths, which…

Numerical Analysis · Mathematics 2026-03-23 Mark F. Adams

Combining Gaussian processes with the expressive power of deep neural networks is commonly done nowadays through deep kernel learning (DKL). Unfortunately, due to the kernel optimization process, this often results in losing their Bayesian…

Machine Learning · Computer Science 2023-05-16 Idan Achituve , Gal Chechik , Ethan Fetaya

In this paper, we focus on the Keller-Segel chemotaxis system in a random heterogeneous domain. We assume that the corresponding diffusion and chemotaxis coefficients are given by stationary ergodic random fields and apply stochastic…

Analysis of PDEs · Mathematics 2016-09-16 Anastasios Matzavinos , Mariya Ptashnyk
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