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Modularisation, repetition, and symmetry are structural features shared by almost all biological neural networks. These features are very unlikely to be found by the means of structural evolution of artificial neural networks. This paper…

Neural and Evolutionary Computing · Computer Science 2017-01-19 Keyan Ghazi-Zahedi

ChatMOF is an autonomous Artificial Intelligence (AI) system that is built to predict and generate metal-organic frameworks (MOFs). By leveraging a large-scale language model (GPT-4 and GPT-3.5-turbo), ChatMOF extracts key details from…

Computation and Language · Computer Science 2023-08-28 Yeonghun Kang , Jihan Kim

This study proposes MCEMOL (Multi-Constrained Evolutionary Molecular Design Framework), a molecular optimization approach integrating rule-based evolution with molecular crossover. MCEMOL employs dual-layer evolution: optimizing…

Neural and Evolutionary Computing · Computer Science 2026-01-16 Shanxian Lin , Wei Xia , Yuichi Nagata , Haichuan Yang

Lots of bio-inspired research works have been conducted in self-adaptive software. They have focused on the external behavior of biological entities without their genetic material that causes this behavior and constitutes the challenge this…

Software Engineering · Computer Science 2019-04-30 Enas Nafar , Said Ghoul

Combinatorial evolution - the creation of new things through the combination of existing things - can be a powerful way to evolve rather than design technical objects such as electronic circuits. Intriguingly, this seems to be an ongoing…

Software Engineering · Computer Science 2021-11-23 Sebastian Fix , Thomas Probst , Oliver Ruggli , Thomas Hanne , Patrik Christen

One way to understand the role history plays on evolutionary trajectories is by giving ancient life a second opportunity to evolve. Our ability to empirically perform such an experiment, however, is limited by current experimental designs.…

Populations and Evolution · Quantitative Biology 2012-09-25 Betul Kacar , Eric Gaucher

The aim of this paper is two-fold. First, we propose a new computational method to investigate the particularities of evolution. Second, we apply this method to a model of gene regulatory networks (GRNs) and explore the evolution of…

Molecular Networks · Quantitative Biology 2022-01-21 Tadamune Kaneko , Macoto Kikuchi

Evolutionary algorithms (EAs) form a popular optimisation paradigm inspired by natural evolution. In recent years the field of evolutionary computation has developed a rigorous analytical theory to analyse their runtime on many illustrative…

Neural and Evolutionary Computing · Computer Science 2015-10-02 Tiago Paixão , Jorge Pérez Heredia , Dirk Sudholt , Barbora Trubenová

We show that neural networks trained by evolutionary reinforcement learning can enact efficient molecular self-assembly protocols. Presented with molecular simulation trajectories, networks learn to change temperature and chemical potential…

Statistical Mechanics · Physics 2020-06-01 Stephen Whitelam , Isaac Tamblyn

The most prominent property of life on Earth is its ability to evolve. It is often taken for granted that self-replication--the characteristic that makes life possible--implies evolvability, but many examples such as the lack of…

Populations and Evolution · Quantitative Biology 2015-11-18 Thomas LaBar , Christoph Adami , Arend Hintze

We introduce a system for experimental evolution consisting of populations of short oligonucleotides (Oli populations) evolving in a modified quantitative Polymerase Chain Reaction (qPCR). It is tractable at the genetic, genomic, phenotypic…

Populations and Evolution · Quantitative Biology 2012-11-20 Sinéad Collins , Andrew Rambaut , Stephen J. Bridgett

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…

Populations and Evolution · Quantitative Biology 2018-07-27 Jacobo Aguirre , Pablo Catalán , José A. Cuesta , Susanna Manrubia

While all organisms on Earth descend from a common ancestor, there is no consensus on whether the origin of this ancestral self-replicator was a one-off event or whether it was only the final survivor of multiple origins. Here we use the…

Populations and Evolution · Quantitative Biology 2017-01-17 Nitash C G , Thomas LaBar , Arend Hintze , Christoph Adami

The relationship between genotype and phenotype plays a crucial role in determining the function and robustness of biological systems. Here the evolution progresses through the change in genotype, whereas the selection is based on the…

Populations and Evolution · Quantitative Biology 2025-02-18 Tuan Minh Pham , Kunihiko Kaneko

Chemotaxis-driven invasions have been proposed across a broad spectrum of biological processes, from cancer to ecology. The influential system of equations introduced by Keller and Segel has proven a popular choice in the modelling of such…

Populations and Evolution · Quantitative Biology 2022-02-02 Tommaso Lorenzi , Kevin J Painter

To unveil the logic of cell from a level of chemical reaction dynamics, we need to clarify how ensemble of chemicals can autonomously produce the set of chemical, without assuming a specific external control echanism. A cell consists of a…

Molecular Networks · Quantitative Biology 2007-05-23 Kunihiko Kaneko

Understanding the evolution of complexity is an important topic in a wide variety of academic fields. Implications of better understanding complexity include increased knowledge of major evolutionary transitions and the properties of living…

Neural and Evolutionary Computing · Computer Science 2022-09-28 Alden H. Wright , Cheyenne L. Laue

Populations can become spatially organised through chemotaxis autoattraction, wherein population members release their own chemoattractant. Standard models of this process usually assume phenotypic homogeneity, but recent studies have shed…

Populations and Evolution · Quantitative Biology 2025-06-05 Tommaso Lorenzi , Kevin J. Painter

In collective robotic systems, the automatic generation of controllers for complex tasks is still a challenging problem. Open-ended evolution of complex robot behaviors can be a possible solution whereby an intrinsic driver for pattern…

Neural and Evolutionary Computing · Computer Science 2019-10-14 Tanja Katharina Kaiser , Heiko Hamann

Our understanding of the evolutionary process has gone a long way since the publication, 150 years ago, of "On the origin of species" by Charles R. Darwin. The XXth Century witnessed great efforts to embrace replication, mutation, and…

Populations and Evolution · Quantitative Biology 2012-02-02 Susanna C. Manrubia , Jose A. Cuesta