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An important problem in the field of bioinformatics is to identify interactive effects among profiled variables for outcome prediction. In this paper, a logistic regression model with pairwise interactions among a set of binary covariates…

Artificial Intelligence · Computer Science 2016-12-30 Easton Li Xu , Xiaoning Qian , Tie Liu , Shuguang Cui

Hypergraphs model higher-order relations that drive real-world decisions, from drug prescriptions to recommendations. A central structural signal in such data, beyond what pairwise relations can express, is interaction compositionality:…

Machine Learning · Computer Science 2026-05-19 Kyrie Zhao , Zehong Wang , Tianyi Ma , Fang Wu , Xiangru Tang , Pietro Lio , Sheng Wang , Yanfang Ye

Topographical structures represent connections between entities and provide a comprehensive design of complex systems. Currently these structures are used to discover correlates of neuronal and haemodynamical activity. In this work, we…

Neurons and Cognition · Quantitative Biology 2022-03-08 David Calhas , Rui Henriques

The loss of limb motion arising from damage to the spinal cord is a disability that could effect people while performing their day-to-day activities. The restoration of limb movement would enable people with spinal cord injury to interact…

Human-Computer Interaction · Computer Science 2022-11-16 Saadat Ullah Khan , Muhammad Majid , Syed Muhammad Anwar

Electroencephalography (EEG) signals are resultants of extremely complex brain activity. Some details of this hidden dynamics might be accessible through e.g. joint distributions $\rho_{\Delta t}$ of signals of pairs of electrodes shifted…

Signal Processing · Electrical Eng. & Systems 2023-05-30 Jarek Duda

Electroencephalograph (EEG) timeseries signals are characterized by significant noise and coarse spatial resolution, which complicates the classification of neurodegenerative diseases. Even SOTA deep learning architectures struggle to…

Machine Learning · Computer Science 2026-05-26 Tawsik Jawad , Gowtham Atluri , Vikram Ravindra

Avoiding overfitting is a central challenge in machine learning, yet many large neural networks readily achieve zero training loss. This puzzling contradiction necessitates new approaches to the study of overfitting. Here we quantify…

Information Theory · Computer Science 2022-10-13 Vudtiwat Ngampruetikorn , David J. Schwab

Knowledge graphs (KGs) composed of users, objects, and tags are widely used in web applications ranging from E-commerce, social media sites to news portals. This paper concentrates on an attractive application which aims to predict the…

Information Retrieval · Computer Science 2020-07-17 Chenyang Li , Xu Chen , Ya Zhang , Siheng Chen , Dan Lv , Yanfeng Wang

Higher-order information theory has become a rapidly growing toolkit in computational neuroscience, motivated by the idea that multivariate dependencies can reveal aspects of neural computation and communication that are invisible to…

Neurons and Cognition · Quantitative Biology 2025-12-03 D. Rebbin , K. J. A. Down , T. F. Varley , R. Ince , A. Canales-Johnson

We study the effect of structured higher-order interactions on the collective behavior of coupled phase oscillators. By combining a hypergraph generative model with dimensionality reduction techniques, we obtain a reduced system of…

Adaptation and Self-Organizing Systems · Physics 2023-03-14 Sabina Adhikari , Juan G. Restrepo , Per Sebastian Skardal

Brain Signals, such as Electroencephalography (EEG), and human languages have been widely explored independently for many downstream tasks, however, the connection between them has not been well explored. In this study, we explore the…

Neurons and Cognition · Quantitative Biology 2024-05-07 William Han , Jielin Qiu , Jiacheng Zhu , Mengdi Xu , Douglas Weber , Bo Li , Ding Zhao

In pseudo-Boolean optimization, a variable interaction graph represents variables as vertices, and interactions between pairs of variables as edges. In black-box optimization, the variable interaction graph may be at least partially…

Artificial Intelligence · Computer Science 2024-10-03 Renato Tinós , Michal W. Przewozniczek , Darrell Whitley , Francisco Chicano

Real-world optimization problems may have a different underlying structure. In black-box optimization, the dependencies between decision variables remain unknown. However, some techniques can discover such interactions accurately. In Large…

Neural and Evolutionary Computing · Computer Science 2022-10-25 Marcin Michal Komarnicki , Michal Witold Przewozniczek , Halina Kwasnicka , Krzysztof Walkowiak

Neural control of grasping arises from nonlinear interactions across multiple brain rhythms, yet EEG-based motor decoding has largely relied on linear, second-order spectral features. Here, we examine whether higher-order cross-frequency…

Signal Processing · Electrical Eng. & Systems 2026-02-05 Sima Ghafoori , Anna Cetera , Ali Rabiee , MH Farhadi , Rahul Singh , Mariusz Furmanek , Yalda Shahriari , Reza Abiri

Electroencephalography (EEG) is widely used to study human brain dynamics, yet its quantitative information capacity remains unclear. Here, we combine information theory and synthetic forward modeling to estimate the mutual information…

Information Theory · Computer Science 2025-10-22 Ishir Rao

Electroencephalography (EEG)-based P300 brain-computer interfaces (BCIs) enable communication without physical movement by detecting stimulus-evoked neural responses. Accurate and efficient decoding remains challenging due to high…

Methodology · Statistics 2026-03-02 Guoxuan Ma , Yuan Zhong , Moyan Li , Yuxiao Nie , Jian Kang

Untapped potential for new forms of human-to-human communication can be found in the active research field of studies on the decoding of brain signals of human speech. A brain-computer interface system can be implemented using…

Human-Computer Interaction · Computer Science 2023-01-20 Soowon Kim , Ji-Won Lee , Young-Eun Lee , Seo-Hyun Lee

The standard approach to modeling the human brain as a complex system is with a network, where the basic unit of interaction is a pairwise link between two brain regions. While powerful, this approach is limited by the inability to assess…

Neurons and Cognition · Quantitative Biology 2023-01-16 Thomas F Varley , Maria Pope , Maria Grazia Puxeddu , Joshua Faskowitz , Olaf Sporns

In real-world recommendation scenarios, users typically engage with platforms through multiple types of behavioral interactions. Multi-behavior recommendation algorithms aim to leverage various auxiliary user behaviors to enhance prediction…

Information Retrieval · Computer Science 2025-07-22 Hengyu Zhang , Chunxu Shen , Xiangguo Sun , Jie Tan , Yanchao Tan , Yu Rong , Hong Cheng , Lingling Yi

We apply a recently developed technique utilizing machine learning for statistical analysis of computational nitrogen K-edge spectra of aqueous triglycine. This method, the emulator-based component analysis, identifies spectrally relevant…

Soft Condensed Matter · Physics 2024-02-14 Eemeli A. Eronen , Anton Vladyka , Florent Gerbon , Christoph. J. Sahle , Johannes Niskanen