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The quantum approximate optimization algorithm (QAOA) is a hybrid variational quantum-classical algorithm that solves combinatorial optimization problems. While there is evidence suggesting that the fixed form of the standard QAOA ansatz is…

Recent advances in quantum computing and the increasing availability of quantum hardware have substantially enhanced the practical relevance of quantum approaches to discrete optimization. Among these, the Quadratic Unconstrained Binary…

Quantum Physics · Physics 2026-02-12 Felix P. Broesamle , Stefan Nickel

Quantum annealing approximately solves combinatorial optimization problems by leveraging the principles of adiabatic quantum systems. In this approach, the system's Hamiltonian evolves from an initial general state to a problem-specific…

The quantum approximate optimization algorithm (QAOA) is a leading candidate algorithm for solving optimization problems on quantum computers. However, the potential of QAOA to tackle classically intractable problems remains unclear. Here,…

The quantum approximate optimization algorithm (QAOA) transforms a simple many-qubit wavefunction into one which encodes a solution to a difficult classical optimization problem. It does this by optimizing the schedule according to which…

Quantum Physics · Physics 2022-06-29 Yunlong Yu , Chenfeng Cao , Carter Dewey , Xiang-Bin Wang , Nic Shannon , Robert Joynt

Quantum annealers can solve QUBO problems efficiently but struggle with continuous optimization tasks like regression due to their discrete nature. We introduce Quadratic Continuous Quantum Optimization (QCQO), an anytime algorithm that…

Quantum Physics · Physics 2026-01-01 Sascha Mücke , Thore Gerlach , Nico Piatkowski

The limited number of qubits is a major bottleneck in Quantum Approximate Optimization Algorithm (QAOA) for large-scale combinatorial optimization in the Noisy Intermediate-Scale Quantum (NISQ) era. To make progress, existing techniques…

Emerging Technologies · Computer Science 2026-04-21 Xiaoyu Ma , Fang Fang , Ximing Xie , Xianbin Wang , Lajos Hanzo

The promise of quantum computing to address complex problems requiring high computational resources has long been hindered by the intrinsic and demanding requirements of quantum hardware development. Nonetheless, the current state of…

Quantum Physics · Physics 2024-07-10 Daniel F Perez-Ramirez

To date, research in quantum computation promises potential for outperforming classical heuristics in combinatorial optimization. However, when aiming at provable optimality, one has to rely on classical exact methods like integer…

Quantum Physics · Physics 2025-03-13 Friedrich Wagner , Jonas Nüßlein , Frauke Liers

The Quadratic Unconstrained Binary Optimization problem (QUBO) has become a unifying model for representing a wide range of combinatorial optimization problems, and for linking a variety of disciplines that face these problems. A new class…

Artificial Intelligence · Computer Science 2017-05-30 Mark Lewis , Fred Glover

The task of Multiple Sequence Alignment (MSA) is a constrained combinatorial optimization problem that is generally considered a complex computational problem. In this paper, we first present a binary encoding of MSA and devise a…

Continuous-variable (CV) quantum systems offer a natural framework for continuous optimization through their infinite-dimensional Hilbert spaces. In this paper, we propose the Complex Continuous-Variable Quantum Approximate Optimization…

Quantum Physics · Physics 2026-04-30 Raneem Madani , Abdel Lisser , Zeno Toffano

In recent years, there is a growing interest in using quantum computers for solving combinatorial optimization problems. In this work, we developed a generic, machine learning-based framework for mapping continuous-space inverse design…

A black-box optimization algorithm such as Bayesian optimization finds extremum of an unknown function by alternating inference of the underlying function and optimization of an acquisition function. In a high-dimensional space, such…

Quantum Physics · Physics 2021-05-03 Syun Izawa , Koki Kitai , Shu Tanaka , Ryo Tamura , Koji Tsuda

The Quantum Approximate Optimization Algorithm (QAOA) is one of the most promising Noisy Intermediate Quantum Algorithms (NISQ) in solving combinatorial optimizations and displays potential over classical heuristic techniques.…

Quantum Physics · Physics 2024-01-18 Arul Rhik Mazumder , Anuvab Sen , Udayon Sen

Solving optimisation problems is a promising near-term application of quantum computers. Quantum variational algorithms leverage quantum superposition and entanglement to optimise over exponentially large solution spaces using an…

Quantum Physics · Physics 2022-10-13 Edric Matwiejew , Jason Pye , Jingbo B. Wang

Variational quantum algorithms offer fascinating prospects for the solution of combinatorial optimization problems using digital quantum computers. However, the achievable performance in such algorithms and the role of quantum correlations…

Quantum Physics · Physics 2024-01-10 Gopal Chandra Santra , Fred Jendrzejewski , Philipp Hauke , Daniel J. Egger

The Quantum Approximate Optimization Algorithm (QAOA) is a hybrid quantum-classical variational algorithm designed to tackle combinatorial optimization problems. Despite its promise for near-term quantum applications, not much is currently…

Quantum Physics · Physics 2020-06-26 Leo Zhou , Sheng-Tao Wang , Soonwon Choi , Hannes Pichler , Mikhail D. Lukin

Quantum approaches to combinatorial optimization problems (COPs) are often limited by the resource demands of Quadratic Unconstrained Binary Optimization (QUBO) encodings, which enlarge circuits through penalty terms and increase qubit and…

Quantum Physics · Physics 2025-11-25 Frederik Koch , Shahram Panahiyan , Rick Mukherjee , Joseph Doetsch , Dieter Jaksch

Combinatorial optimization is a promising area for achieving quantum speedup. Quantum approximate optimization algorithm (QAOA) is designed to search for low-energy states of the Ising model, which correspond to near-optimal solutions of…

Quantum Physics · Physics 2025-10-14 Tatsuhiko Shirai , Nozomu Togawa