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Large-scale cell microscopy screens are used in drug discovery and molecular biology research to study the effects of millions of chemical and genetic perturbations on cells. To use these images in downstream analysis, we need models that…

Results in interpretability suggest that large vision and language models learn implicit linear encodings when models are biased by in-context prompting. However, the existence of similar linear representations in more general adaptation…

Machine Learning · Computer Science 2025-12-18 Darrin O' Brien , Dhikshith Gajulapalli , Eric Xia

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Vision Transformers have shown great promise recently for many vision tasks due to the insightful architecture design and attention mechanism. By revisiting the self-attention responses in Transformers, we empirically observe two…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Xu Ma , Huan Wang , Can Qin , Kunpeng Li , Xingchen Zhao , Jie Fu , Yun Fu

Recent advances in neuroimaging have deepened our understanding of the brain's complex functional and structural organization. Among these, functional Magnetic Resonance Imaging (fMRI) - particularly resting-state fMRI (rs-fMRI) - has…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 M. Moein Esfahani , Sepehr Salem Ghahfarokhi , Mohammed Alser , Jingyu Liu , Vince Calhoun

This survey explores the transformative impact of foundation models (FMs) in artificial intelligence, focusing on their integration with federated learning (FL) for advancing biomedical research. Foundation models such as ChatGPT, LLaMa,…

Machine Learning · Computer Science 2024-05-14 Xingyu Li , Lu Peng , Yuping Wang , Weihua Zhang

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Magnetic Resonance Imaging (MRI) is a noninvasive imaging technique that provides exquisite soft-tissue contrast without using ionizing radiation. The clinical application of MRI may be limited by long data acquisition times; therefore, MR…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Shen Zhao , Lee C. Potter , Kiryung Lee , Rizwan Ahmad

As the quality of few shot facial animation from landmarks increases, new applications become possible, such as ultra low bandwidth video chat compression with a high degree of realism. However, there are some important challenges to tackle…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Maxime Oquab , Daniel Haziza , Ludovic Schwartz , Tao Xu , Katayoun Zand , Rui Wang , Peirong Liu , Camille Couprie

The emergence of foundation models in neuroimaging is driven by the increasing availability of large-scale and heterogeneous brain imaging datasets. Recent advances in self-supervised learning, particularly reconstruction-based objectives,…

Machine Learning · Computer Science 2025-11-04 Ruthwik Reddy Doodipala , Pankaj Pandey , Carolina Torres Rojas , Manob Jyoti Saikia , Ranganatha Sitaram

Purpose: To propose a flexible and scalable imaging transformer (IT) architecture with three attention modules for multi-dimensional imaging data and apply it to MRI denoising with very low input SNR. Methods: Three independent attention…

Foundation models have revolutionized artificial intelligence across numerous domains, yet their transformative potential remains largely untapped in Extreme Multi-label Classification (XMC). Queries in XMC are associated with relevant…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Diego Ortego , Marlon Rodríguez , Mario Almagro , Kunal Dahiya , David Jiménez , Juan C. SanMiguel

Understanding functional representations within higher visual cortex is a fundamental question in computational neuroscience. While artificial neural networks pretrained on large-scale datasets exhibit striking representational alignment…

Medical imaging tasks are very challenging due to the lack of publicly available labeled datasets. Hence, it is difficult to achieve high performance with existing deep-learning models as they require a massive labeled dataset to be trained…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Anubhav Gupta , Islam Osman , Mohamed S. Shehata , John W. Braun

Masked AutoEncoders (MAE) have emerged as a robust self-supervised framework, offering remarkable performance across a wide range of downstream tasks. To increase the difficulty of the pretext task and learn richer visual representations,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Carlos Hinojosa , Shuming Liu , Bernard Ghanem

Unrolled neural networks have enabled state-of-the-art reconstruction performance and fast inference times for the accelerated magnetic resonance imaging (MRI) reconstruction task. However, these approaches depend on fully-sampled scans as…

Image and Video Processing · Electrical Eng. & Systems 2022-04-25 Beliz Gunel , Arda Sahiner , Arjun D. Desai , Akshay S. Chaudhari , Shreyas Vasanawala , Mert Pilanci , John Pauly

Large, pretrained models are commonly finetuned with imagery that is heavily augmented to mimic different conditions and scales, with the resulting models used for various tasks with imagery from a range of spatial scales. Such models…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Colorado J. Reed , Ritwik Gupta , Shufan Li , Sarah Brockman , Christopher Funk , Brian Clipp , Kurt Keutzer , Salvatore Candido , Matt Uyttendaele , Trevor Darrell

In this work, we present a novel direction to build an image tokenizer directly on top of a frozen vision foundation model, which is a largely underexplored area. Specifically, we employ a frozen vision foundation model as the encoder of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Anlin Zheng , Xin Wen , Xuanyang Zhang , Chuofan Ma , Tiancai Wang , Gang Yu , Xiangyu Zhang , Xiaojuan Qi

Magnetic Resonance Imaging (MRI) is indispensable in clinical practice but remains constrained by fragmented, multi-stage workflows encompassing acquisition, reconstruction, segmentation, detection, diagnosis, and reporting. While deep…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xingxin He , Aurora Rofena , Ruimin Feng , Haozhe Liao , Zhaoye Zhou , Albert Jang , Fang Liu

Motivation: Conventional echo planar imaging(EPI) based functional MRI(fMRI) uses the BOLD contrast to map activity changes in human brains. Introducing an efficient ZTE sequence for functional brain mapping can help address limitations of…

Medical Physics · Physics 2025-10-28 Ali Caglar Ozen , Shuai Liu , Serhat Ilbey , Michael Bock , Uzay Emir , Yen-Yu Ian Shih