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There is substantial interest in developing artificial intelligence systems to support radiologists across tasks ranging from segmentation to report generation. Existing computed tomography (CT) foundation models have largely focused on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Rubén Moreno-Aguado , Alba Magallón , Victor Moreno , Yingying Fang , Guang Yang

Magnetic resonance imaging (MRI) is critically important for brain mapping in both scientific research and clinical studies. Precise segmentation of brain tumors facilitates clinical diagnosis, evaluations, and surgical planning. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Rui Nian , Guoyao Zhang , Yao Sui , Yuqi Qian , Qiuying Li , Mingzhang Zhao , Jianhui Li , Ali Gholipour , Simon K. Warfield

Neural decoding, the process of understanding how brain activity corresponds to different stimuli, has been a primary objective in cognitive sciences. Over the past three decades, advances in functional Magnetic Resonance Imaging (fMRI) and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Yanchen Wang , Adam Turnbull , Tiange Xiang , Yunlong Xu , Sa Zhou , Adnan Masoud , Shekoofeh Azizi , Feng Vankee Lin , Ehsan Adeli

This paper shows that masked autoencoders (MAE) are scalable self-supervised learners for computer vision. Our MAE approach is simple: we mask random patches of the input image and reconstruct the missing pixels. It is based on two core…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Kaiming He , Xinlei Chen , Saining Xie , Yanghao Li , Piotr Dollár , Ross Girshick

Frontier artificial intelligence (AI) models, such as OpenAI's GPT-5 and Meta's DINOv3, have advanced rapidly through training on internet-scale public data, yet such systems lack access to private clinical data. Neuroimaging, in…

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

Reconstructions of visual perception from brain activity have improved tremendously, but the practical utility of such methods has been limited. This is because such models are trained independently per subject where each subject requires…

Few-shot learning has been studied to adapt models to tasks with very few samples. It holds profound significance, particularly in clinical tasks, due to the high annotation cost of medical images. Several works have explored few-shot…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Kaipeng Zheng , Weiran Huang , Lichao Sun

A cognitive map is an internal model which encodes the abstract relationships among entities in the world, giving humans and animals the flexibility to adapt to new situations, with a strong out-of-distribution (OOD) generalization that…

Machine Learning · Computer Science 2026-05-12 Victor Rambaud , Salvador Mascarenhas , Yair Lakretz

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by disruptions in brain connectivity. Functional MRI (fMRI) offers a non-invasive window into large-scale neural dynamics by measuring…

Machine Learning · Computer Science 2025-08-20 Mohammad Izadi , Mehran Safayani

Foundation models are transforming neuroscience but are often prohibitively large, data-hungry, and difficult to deploy. Here, we introduce BrainSymphony, a lightweight and parameter-efficient foundation model with plug-and-play integration…

Quantitative Methods · Quantitative Biology 2026-02-13 Moein Khajehnejad , Forough Habibollahi , Devon Stoliker , Adeel Razi

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Zelong Liu , Andrew Tieu , Nikhil Patel , Georgios Soultanidis , Louisa Deyer , Ying Wang , Sean Huver , Alexander Zhou , Yunhao Mei , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

We introduce SPECTRE, a fully transformer-based foundation model for volumetric computed tomography (CT). Our Self-Supervised & Cross-Modal Pretraining for CT Representation Extraction (SPECTRE) approach utilizes scalable 3D Vision…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Cris Claessens , Christiaan Viviers , Giacomo D'Amicantonio , Egor Bondarev , Fons van der Sommen

The limited data availability and the low signal-to-noise ratio of fMRI signals lead to the challenging task of fMRI-to-image retrieval. State-of-the-art MindEye remarkably improves fMRI-to-image retrieval performance by leveraging a large…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Zixuan Gong , Qi Zhang , Guangyin Bao , Lei Zhu , Ke Liu , Liang Hu , Duoqian Miao , Yu Zhang

Due to the prevalence of scale variance in nature images, we propose to use image scale as a self-supervised signal for Masked Image Modeling (MIM). Our method involves selecting random patches from the input image and downsampling them to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Zhiming Wang , Lin Gu , Feng Lu

Vision Transformers (ViT) become widely-adopted architectures for various vision tasks. Masked auto-encoding for feature pretraining and multi-scale hybrid convolution-transformer architectures can further unleash the potentials of ViT,…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Peng Gao , Teli Ma , Hongsheng Li , Ziyi Lin , Jifeng Dai , Yu Qiao

Capturing dynamic spatiotemporal neural activity is essential for understanding large-scale brain mechanisms. Functional magnetic resonance imaging (fMRI) provides high-resolution cortical representations that form a strong basis for…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Wanying Qu , Jianxiong Gao , Wei Wang , Yanwei Fu

Medical image challenges have played a transformative role in advancing the field, catalyzing innovation and establishing new performance benchmarks. Image registration, a foundational task in neuroimaging, has similarly advanced through…

The pre-trained transformer demonstrates remarkable generalization ability in natural image processing. However, directly transferring it to magnetic resonance images faces two key challenges: the inability to adapt to the specificity of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jingkai Li , Xiaoze Tian , Yuhang Shen , Jia Wang , Dianjie Lu , Guijuan Zhang , Zhuoran Zheng

The Masked Autoencoder (MAE) has recently demonstrated effectiveness in pre-training Vision Transformers (ViT) for analyzing natural images. By reconstructing complete images from partially masked inputs, the ViT encoder gathers contextual…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Badhan Kumar Das , Gengyan Zhao , Han Liu , Thomas J. Re , Dorin Comaniciu , Eli Gibson , Andreas Maier