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Recent success in Artificial Intelligence (AI) and Machine Learning (ML) allow problem solving automatically without any human intervention. Autonomous approaches can be very convenient. However, in certain domains, e.g., in the medical…

Artificial Intelligence · Computer Science 2021-03-03 Andreas Holzinger , André Carrington , Heimo Müller

Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex,…

\textbf{Background:} Regulatory frameworks for AI in healthcare, including the EU AI Act and FDA guidance on AI/ML-based medical devices, require clinical decision support to demonstrate not only accuracy but auditability. Existing formal…

Artificial Intelligence · Computer Science 2026-04-24 Michael Bouzinier , Sergey Trifonov , Michael Chumack , Eugenia Lvova , Dmitry Etin

This paper presents a novel application of Genetic Algorithms(GAs) to quantify the performance of Platform as a Service (PaaS), a cloud service model that plays a critical role in both industry and academia. While Cloud benchmarks are not…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-08-28 Jeff Kinnison , Sekou L. Remy

Deep neural networks for medical image classification often fail to generalize consistently in clinical practice due to violations of the i.i.d. assumption and opaque decision-making. This paper examines interpretability in deep neural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Mohammad Hossein Najafi , Mohammad Morsali , Mohammadreza Pashanejad , Saman Soleimani Roudi , Mohammad Norouzi , Saeed Bagheri Shouraki

The rapid proliferation of large language model (LLM)-based agentic systems raises critical concerns regarding digital sovereignty, environmental sustainability, regulatory compliance, and ethical alignment. Whilst existing frameworks…

Artificial Intelligence (AI) is rapidly embedded in critical decision-making systems, however their foundational ``black-box'' models require eXplainable AI (XAI) solutions to enhance transparency, which are mostly oriented to experts,…

Machine Learning · Computer Science 2025-06-17 Eva Paraschou , Ioannis Arapakis , Sofia Yfantidou , Sebastian Macaluso , Athena Vakali

GraphFlow is a visual workflow system designed to improve the reliability of agentic AI automation in multi-step, mission-critical processes. In these workflows, small errors compound rapidly: under an idealized model of independent steps,…

Artificial Intelligence · Computer Science 2026-05-15 Drewry H. Morris , Luis Valles , Reza Hosseini Ghomi

As large language models are deployed in high-stakes enterprise applications, from healthcare to finance, ensuring adherence to organization-specific policies has become essential. Yet existing safety evaluations focus exclusively on…

Artificial Intelligence · Computer Science 2026-01-06 Dasol Choi , DongGeon Lee , Brigitta Jesica Kartono , Helena Berndt , Taeyoun Kwon , Joonwon Jang , Haon Park , Hwanjo Yu , Minsuk Kahng

Explainability remains a critical challenge in artificial intelligence (AI) systems, particularly in high stakes domains such as healthcare, finance, and decision support, where users must understand and trust automated reasoning.…

Human-Computer Interaction · Computer Science 2025-08-05 Rukshani Somarathna , Madhawa Perera , Tom Gedeon , Matt Adcock

Explainability is critical for the clinical adoption of medical visual question answering (VQA) systems, as physicians require transparent reasoning to trust AI-generated diagnoses. We present MedXplain-VQA, a comprehensive framework…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hai-Dang Nguyen , Minh-Anh Dang , Minh-Tan Le , Minh-Tuan Le

Comprehensive and accurate evaluation of general-purpose AI systems such as large language models allows for effective mitigation of their risks and deepened understanding of their capabilities. Current evaluation methodology, mostly based…

Artificial Intelligence · Computer Science 2024-01-01 Xiting Wang , Liming Jiang , Jose Hernandez-Orallo , David Stillwell , Luning Sun , Fang Luo , Xing Xie

Transportation safety analysis requires integrating crash records, roadway attributes, and geospatial data through GIS-based workflows, but access remains uneven across agencies and community stakeholders. Technical prerequisites create a…

Computation and Language · Computer Science 2026-05-22 Mahdi Azhdari , Eric J. Gonzales

Recent developments in Generative Artificial Intelligence (GenAI) have created significant uncertainty in education, particularly in terms of assessment practices. Against this backdrop, we present an updated version of the AI Assessment…

Computers and Society · Computer Science 2025-10-01 Mike Perkins , Jasper Roe , Leon Furze

This paper reports a case study on how explainability requirements were elicited during the development of an AI system for predicting cerebral palsy (CP) risk in infants. Over 18 months, we followed a development team and hospital…

Software Engineering · Computer Science 2026-01-06 Tor Sporsem , Stine Rasdal Finserås , Lars Adde , Inga Strümke

Objective: To assess the performance of the OpenAI GPT API in accurately and efficiently identifying relevant titles and abstracts from real-world clinical review datasets and compare its performance against ground truth labelling by two…

Computation and Language · Computer Science 2023-10-09 Eddie Guo , Mehul Gupta , Jiawen Deng , Ye-Jean Park , Mike Paget , Christopher Naugler

The rapid evolution of generative AI, from GANs to modern diffusion models, has resulted in increasingly subtle discriminative clues. These fine-grained signals are often overshadowed by dominant, high-fidelity image content (e.g., the main…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Xiaoyu Zhou , Jianwei Fei , Peipeng Yu , Jingchang Xie , Chong Cheng , Zhihua Xia

Explainability and Safety engender Trust. These require a model to exhibit consistency and reliability. To achieve these, it is necessary to use and analyze data and knowledge with statistical and symbolic AI methods relevant to the AI…

Artificial Intelligence · Computer Science 2023-12-13 Manas Gaur , Amit Sheth

What values, evidence preferences, and source trust hierarchies do AI systems actually exhibit when facing structured dilemmas? We present the first large-scale empirical mapping of AI decision-making across all three layers of the…

Artificial Intelligence · Computer Science 2026-04-14 Seulki Lee

While Large Language Models (LLMs) achieve superhuman performance on standardized medical licensing exams, these static benchmarks have become saturated and increasingly disconnected from the functional requirements of clinical workflows.…

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