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The Quantum Approximate Optimization Algorithm (QAOA) is a promising candidate algorithm for demonstrating quantum advantage in optimization using near-term quantum computers. However, QAOA has high requirements on gate fidelity due to the…

Quantum Physics · Physics 2023-03-20 Xiaoyuan Liu , Ruslan Shaydulin , Ilya Safro

High error rates and limited fidelity of quantum gates in near-term quantum devices are the central obstacles to successful execution of the Quantum Approximate Optimization Algorithm (QAOA). In this paper we introduce an…

Quantum Physics · Physics 2022-06-16 Ruslan Shaydulin , Alexey Galda

In this paper, we propose a quantum-native formulation of maximum likelihood detection (MLD) for overloaded multiple-input multiple-output (MIMO) systems in a random access channel, where numerous user terminals share the same channel…

Signal Processing · Electrical Eng. & Systems 2026-05-20 Hyoga Iizumi , Naoki Ishikawa , Shunsuke Uehashi , Kota Nakamura , Shusaku Umeda , Toshiaki Koike-Akino

Constrained binary optimization aims to find an optimal assignment to minimize or maximize the objective meanwhile satisfying the constraints, which is a representative NP problem in various domains, including transportation, scheduling,…

Quantum Physics · Physics 2025-08-18 Debin Xiang , Qifan Jiang , Liqiang Lu , Siwei Tan , Jianwei Yin

We present new advances towards achieving exponential quantum speedups for solving optimization problems by low-depth quantum algorithms. Specifically, we focus on families of combinatorial optimization problems that exhibit symmetry and…

Quantum Physics · Physics 2025-02-25 Ashley Montanaro , Leo Zhou

The quantum approximate optimization algorithm (QAOA) is a general-purpose algorithm for combinatorial optimization. In this paper, we analyze the performance of the QAOA on a statistical estimation problem, namely, the spiked tensor model,…

Quantum Physics · Physics 2026-02-19 Leo Zhou , Joao Basso , Song Mei

The quantum approximate optimization algorithm (QAOA) is a quantum heuristic for combinatorial optimization that has been demonstrated to scale better than state-of-the-art classical solvers for some problems. For a given problem instance,…

Quantum Physics · Physics 2026-02-23 Tianyi Hao , Zichang He , Ruslan Shaydulin , Jeffrey Larson , Marco Pistoia

Quantum devices use qubits to represent information, which allows them to exploit important properties from quantum physics, specifically superposition and entanglement. As a result, quantum computers have the potential to outperform the…

Quantum Physics · Physics 2024-02-14 Abhijeet Ghoshal , Yan Li , Syam Menon , Sumit Sarkar

The design of fast algorithms for combinatorial optimization greatly contributes to a plethora of domains such as logistics, finance, and chemistry. Quantum approximate optimization algorithms (QAOAs), which utilize the power of quantum…

Quantum Physics · Physics 2022-05-25 Zeqiao Zhou , Yuxuan Du , Xinmei Tian , Dacheng Tao

We introduce a novel quantum optimization paradigm: the Fixed-Parameter-Count Quantum Approximate Optimization Algorithm (FPC-QAOA). It is a scalable variational framework that maintains a constant number of trainable parameters regardless…

Establishing quantum advantage for variational quantum algorithms is an important direction in quantum computing. In this work, we apply the Quantum Approximate Optimisation Algorithm (QAOA) -- a popular variational quantum algorithm for…

Quantum Physics · Physics 2024-01-08 Andrew El-Kadi , Roberto Bondesan

The quantum approximate optimization algorithm (QAOA) and quantum annealing are two of the most popular quantum optimization heuristics. While QAOA is known to be able to approximate quantum annealing, the approximation requires QAOA angles…

Quantum Physics · Physics 2025-10-09 Sami Boulebnane , James Sud , Ruslan Shaydulin , Marco Pistoia

The Quantum Approximate Optimization Algorithm (QAOA) has been suggested as a promising candidate for the solution of combinatorial optimization problems. Yet, whether - or under what conditions - it may offer an advantage compared to…

Quantum Physics · Physics 2025-04-14 Vanessa Dehn , Martin Zaefferer , Gerhard Hellstern , Florentin Reiter , Thomas Wellens

The Quantum Approximate Optimization Algorithm (QAOA) has shown promise in solving combinatorial optimization problems by leveraging quantum computational power. We propose a simple approach, the Two-Step QAOA, which aims to improve the…

Quantum Physics · Physics 2025-02-25 Yuichiro Minato

We propose and study Th-QAOA (pronounced Threshold QAOA), a variation of the Quantum Alternating Operator Ansatz (QAOA) that replaces the standard phase separator operator, which encodes the objective function, with a threshold function…

Quantum Physics · Physics 2022-06-06 John Golden , Andreas Bärtschi , Daniel O'Malley , Stephan Eidenbenz

Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos

The Quantum Approximate Optimization Algorithm (QAOA) is a prominent quantum algorithm designed to find approximate solutions to combinatorial optimization problems, which are challenging for classical computers. In the current era, where…

Encoding combinatorial optimization problems into physically meaningful Hamiltonians with tractable energy landscapes forms the foundation of quantum optimization. Numerous works have studied such efficient encodings for the class of…

Quantum Physics · Physics 2026-02-12 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

Quantum Approximate Optimization Algorithm (QAOA) provides a way to solve combinatorial optimization problems using quantum computers. QAOA circuits consist of time evolution operators by the cost Hamiltonian and of state mixing operators,…

Quantum Physics · Physics 2024-05-02 Ryo Sakai , Hiromichi Matsuyama , Wai-Hong Tam , Yu Yamashiro , Keisuke Fujii

Noisy intermediate-scale quantum computers (NISQ computers) are now readily available, motivating many researchers to experiment with Variational Quantum Algorithms (VQAs). Among them, the Quantum Approximate Optimization Algorithm (QAOA)…

Optimization and Control · Mathematics 2024-08-13 Camille Grange , Michael Poss , Eric Bourreau