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The numerical availability of statistical inference methods for a modern and robust analysis of longitudinal- and multivariate data in factorial experiments is an essential element in research and education. While existing approaches that…

Computation · Statistics 2018-01-25 Sarah Friedrich , Frank Konietschke , Markus Pauly

Despite recent progress, reinforcement learning (RL)-based fine-tuning of diffusion models often struggles with generalization, composability, and robustness against reward hacking. Recent studies have explored prompt refinement as a…

Machine Learning · Computer Science 2026-03-26 Suhyeon Lee , Jong Chul Ye

We introduce mixed model trace regression (MMTR), a mixed model linear regression extension for scalar responses and high-dimensional matrix-valued covariates. MMTR's fixed effects component is equivalent to trace regression, with an…

Methodology · Statistics 2025-03-19 Ian Hultman , Sanvesh Srivastava

To improve precision of estimation and power of testing hypothesis for an unconditional treatment effect in randomized clinical trials with binary outcomes, researchers and regulatory agencies recommend using g-computation as a reliable…

Methodology · Statistics 2023-03-29 Ting Ye , Marlena Bannick , Yanyao Yi , Jun Shao

Motivated by challenges in the analysis of biomedical data and observational studies, we develop statistical boosting for the general class of bivariate distributional copula regression with arbitrary marginal distributions, which is suited…

Methodology · Statistics 2024-03-05 Guillermo Briseño Sanchez , Nadja Klein , Hannah Klinkhammer , Andreas Mayr

Randomized experiments or randomized controlled trials (RCTs) are gold standards for causal inference, yet cost and sample-size constraints limit power. We introduce CALM (Causal Analysis leveraging Language Models), a statistical framework…

Methodology · Statistics 2025-12-09 Xinrui Ruan , Xinwei Ma , Yingfei Wang , Waverly Wei , Jingshen Wang

Covariate adjustment is an approach to improve the precision of trial analyses by adjusting for baseline variables that are prognostic of the primary endpoint. Motivated by the SEARCH Universal HIV Test-and-Treat Trial (2013-2017), we tell…

Methodology · Statistics 2025-12-16 Laura B. Balzer , Mark J. van der Laan , Maya L. Petersen

Fine-tuning pre-trained language models (PLMs), e.g., SciBERT, generally requires large numbers of annotated data to achieve state-of-the-art performance on a range of NLP tasks in the scientific domain. However, obtaining the fine-tune…

Computation and Language · Computer Science 2025-12-30 Jiawei Liu , Zi Xiong , Yi Jiang , Yongqiang Ma , Wei Lu , Yong Huang , Qikai Cheng

Recent paradigms in Random Projection Layer (RPL)-based continual representation learning have demonstrated superior performance when building upon a pre-trained model (PTM). These methods insert a randomly initialized RPL after a PTM to…

Machine Learning · Computer Science 2026-03-20 Ruilin Li , Heming Zou , Xiufeng Yan , Zheming Liang , Jie Yang , Chenliang Li , Xue Yang

We present fastrerandomize, an R package for fast, scalable rerandomization in experimental design. Rerandomization improves precision by discarding treatment assignments that fail a prespecified covariate-balance criterion, but existing…

Computation · Statistics 2026-01-09 Rebecca Goldstein , Connor T. Jerzak , Aniket Kamat , Fucheng Warren Zhu

Linear mixed models (LMMs) are used as an important tool in the data analysis of repeated measures and longitudinal studies. The most common form of LMMs utilize a normal distribution to model the random effects. Such assumptions can often…

Methodology · Statistics 2016-02-16 Hien D. Nguyen , Geoffrey J. McLachlan

Contextual sensing and delivery of digital interventions to improve health outcomes have gained significant traction in behavioral and psychiatric studies. Micro-randomized trials (MRTs) are a common experimental design for obtaining…

Methodology · Statistics 2025-04-01 Jieru Shi , Zhenke Wu , Walter Dempsey

Joint modeling has become increasingly popular for characterizing the association between one or more longitudinal biomarkers and competing risks time-to-event outcomes. However, semiparametric multivariate joint modeling for large-scale…

Methodology · Statistics 2025-06-17 Shanpeng Li , Emily Ouyang , Jin Zhou , Xinping Cui , Gang Li

Permutation methods are commonly used to test significance of regressors of interest in general linear models (GLMs) for functional (image) data sets, in particular for neuroimaging applications as they rely on mild assumptions. Permutation…

Methodology · Statistics 2021-11-23 Tomas Mrkvicka , Mari Myllymaki , Mikko Kuronen , Naveen Naidu Narisetty

In observational studies, propensity scores are commonly estimated by maxi- mum likelihood but may fail to balance high-dimensional pre-treatment covariates even after specification search. We introduce a general framework that unifies and…

Methodology · Statistics 2017-03-22 Qingyuan Zhao

Learning to rank (LTR) plays a crucial role in various Information Retrieval (IR) tasks. Although supervised LTR methods based on fine-grained relevance labels (e.g., document-level annotations) have achieved significant success, their…

Information Retrieval · Computer Science 2025-08-21 Yiteng Tu , Zhichao Xu , Tao Yang , Weihang Su , Yujia Zhou , Yiqun Liu , Fen Lin , Qin Liu , Qingyao Ai

Many applications of machine learning involve the analysis of large data frames-matrices collecting heterogeneous measurements (binary, numerical, counts, etc.) across samples-with missing values. Low-rank models, as studied by Udell et al.…

Machine Learning · Statistics 2018-12-21 Geneviève Robin , Hoi-To Wai , Julie Josse , Olga Klopp , Éric Moulines

Nonparametric covariate adjustment is considered for log-rank type tests of treatment effect with right-censored time-to-event data from clinical trials applying covariate-adaptive randomization. Our proposed covariate-adjusted log-rank…

Methodology · Statistics 2023-01-23 Ting Ye , Jun Shao , Yanyao Yi

For many high-dimensional studies, additional information on the variables, like (genomic) annotation or external p-values, is available. In the context of binary and continuous prediction, we develop a method for adaptive group-regularized…

Large language models (LLMs) have demonstrated impressive success in a wide range of natural language processing (NLP) tasks due to their extensive general knowledge of the world. Recent works discovered that the performance of LLMs is…

Computation and Language · Computer Science 2024-11-25 Yuze Liu , Tingjie Liu , Tiehua Zhang , Youhua Xia , Jinze Wang , Zhishu Shen , Jiong Jin , Fei Richard Yu