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The true power of computational research typically can lay in either what it accomplishes or what it enables others to accomplish. In this work, both avenues are simultaneously embraced across several distinct efforts existing at three…

Materials Science · Physics 2024-11-06 Adam M. Krajewski

Discovering new solid-state materials requires rapidly exploring the vast space of crystal structures and locating stable regions. Generating stable materials with desired properties and compositions is extremely difficult as we search for…

Machine Learning · Computer Science 2024-11-08 Tri Minh Nguyen , Sherif Abdulkader Tawfik , Truyen Tran , Sunil Gupta , Santu Rana , Svetha Venkatesh

Consider a movie studio aiming to produce a set of new movies for summer release: What types of movies it should produce? Who would the movies appeal to? How many movies should it make? Similar issues are encountered by a variety of…

Information Retrieval · Computer Science 2018-08-06 Vinh Vo Thanh , Harold Soh

Inverse design of heterogeneous material microstructures is a fundamentally ill-posed and famously computationally expensive problem. This is exacerbated by the high-dimensional design spaces associated with finely resolved images,…

Machine Learning · Computer Science 2026-03-17 Reza T. Batley , Sourav Saha

Function in natural systems arises from one-dimensional sequences forming three-dimensional structures with specific properties. However, current generative models suffer from critical limitations: training objectives seldom target function…

Equivariant diffusion models have emerged as the prevailing approach for generating novel crystal materials due to their ability to leverage the physical symmetries of periodic material structures. However, current models do not effectively…

Machine Learning · Computer Science 2025-03-04 Kishalay Das , Subhojyoti Khastagir , Pawan Goyal , Seung-Cheol Lee , Satadeep Bhattacharjee , Niloy Ganguly

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

Artificial intelligence has shown remarkable success in materials discovery and property prediction, particularly for crystalline and polymer systems where material properties and structures are dominated by discrete graph representations.…

Machine Learning · Computer Science 2026-05-20 Xinyao Li , Hangwei Qian , Jingjing Li , Lei Zhu , Ivor Tsang

Unified multimodal models have recently shown remarkable gains in both capability and versatility, yet most leading systems are still trained from scratch and require substantial computational resources. In this paper, we show that…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zeyu Wang , Zilong Chen , Chenhui Gou , Feng Li , Chaorui Deng , Deyao Zhu , Kunchang Li , Weihao Yu , Haoqin Tu , Haoqi Fan , Cihang Xie

Understanding how living organisms spontaneously develop complex functional structures inspires innovative approaches in engineering design. Here, we introduce a decentralized generative model based on morphogenesis to autonomously grow…

Applied Physics · Physics 2025-09-15 Thomas Fromentèze , Philippe Michaud , Ali Hassny , Vincent Pateloup

Metamaterials are a new generation of advanced materials, exhibiting engineered microstructures that enable customized material properties not found in nature. The dynamics of metamaterials are particularly fascinating, promising the…

Applied Physics · Physics 2025-07-03 Charles Dorn , Vignesh Kannan , Ute Drechsler , Dennis M. Kochmann

In addition to the forward inference of materials properties using machine learning, generative deep learning techniques applied on materials science allow the inverse design of materials, i.e., assessing the…

Materials Science · Physics 2024-10-01 Teng Long , Yixuan Zhang , Hongbin Zhang

Modern generative models achieve excellent quality in a variety of tasks including image or text generation and chemical molecule modeling. However, existing methods often lack the essential ability to generate examples with requested…

While federated learning leverages distributed client resources, it faces challenges due to heterogeneous client capabilities. This necessitates allocating models suited to clients' resources and careful parameter aggregation to accommodate…

Machine Learning · Computer Science 2024-10-04 Yujin Shin , Kichang Lee , Sungmin Lee , You Rim Choi , Hyung-Sin Kim , JeongGil Ko

Amorphous materials are solids that lack long-range atomic order but possess complex short- and medium-range order. Unlike crystalline materials that can be described by unit cells containing few up to hundreds of atoms, amorphous materials…

Machine Learning · Computer Science 2026-04-01 Yan Lin , Jonas A. Finkler , Tao Du , Jilin Hu , Morten M. Smedskjaer

While DeepMind has tentatively solved protein folding, its inverse problem -- protein design which predicts protein sequences from their 3D structures -- still faces significant challenges. Particularly, the lack of large-scale standardized…

Quantitative Methods · Quantitative Biology 2022-02-15 Zhangyang Gao , Cheng Tan , Stan Z. Li

Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Izabela Horvath , Johannes C. Paetzold , Oliver Schoppe , Rami Al-Maskari , Ivan Ezhov , Suprosanna Shit , Hongwei Li , Ali Ertuerk , Bjoern H. Menze

Discovering new physical products and processes often demands enormous experimentation and expensive simulation. To design a new product with certain target characteristics, an extensive search is performed in the design space by trying out…

Machine Learning · Statistics 2018-11-16 Phuoc Nguyen , Truyen Tran , Sunil Gupta , Santu Rana , Svetha Venkatesh

To improve business efficiency and minimize costs, Artificial Intelligence (AI) practitioners have adopted a shift from formulating models from scratch towards sharing pretrained models. The pretrained models are then aggregated into a…

Neural and Evolutionary Computing · Computer Science 2025-05-12 Anthony Kiggundu , Dennis Krummacker , Hans D. Schotten

Generative models have demonstrated strong performance in conditional settings and can be viewed as a form of data compression, where the condition serves as a compact representation. However, their limited controllability and…

Machine Learning · Computer Science 2025-07-04 Xiao Li , Liangji Zhu , Anand Rangarajan , Sanjay Ranka