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Diffeomorphic image registration, offering smooth transformation and topology preservation, is required in many medical image analysis tasks.Traditional methods impose certain modeling constraints on the space of admissible transformations…

Computer Vision and Pattern Recognition · Computer Science 2022-11-03 Kun Han , Shanlin sun , Xiangyi Yan , Chenyu You , Hao Tang , Junayed Naushad , Haoyu Ma , Deying Kong , Xiaohui Xie

We present an implementation of a new approach to diffeomorphic non-rigid registration of medical images. The method is based on optical flow and warps images via gradient flow with the standard $L^2$ inner product. To compute the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Daniel Grzech , Loïc le Folgoc , Mattias P. Heinrich , Bishesh Khanal , Jakub Moll , Julia A. Schnabel , Ben Glocker , Bernhard Kainz

Conventional deformable registration methods aim at solving an optimization model carefully designed on image pairs and their computational costs are exceptionally high. In contrast, recent deep learning based approaches can provide fast…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Risheng Liu , Zi Li , Xin Fan , Chenying Zhao , Hao Huang , Zhongxuan Luo

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung

The variational principle (VP) is designed to generate non-folding grids (diffeomorphisms) with prescribed Jacobian determinant (JD) and curl. Its solution pool of the original VP is based on an additive formulation and, consequently, is…

Numerical Analysis · Mathematics 2021-05-20 Zicong Zhou , Guojun Liao

Quantification of uncertainty in deep-neural-networks (DNN) based image registration algorithms plays a critical role in the deployment of image registration algorithms for clinical applications such as surgical planning, intraoperative…

Computer Vision and Pattern Recognition · Computer Science 2022-06-10 Samah Khawaled , Moti Freiman

This paper presents NimbleReg, a light-weight deep-learning (DL) framework for diffeomorphic image registration leveraging surface representation of multiple segmented anatomical regions. Deep learning has revolutionized image registration…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Antoine Legouhy , Ross Callaghan , Nolah Mazet , Vivien Julienne , Hojjat Azadbakht , Hui Zhang

Many registration problems are ill-posed in homogeneous or noisy regions, and dense voxel-wise decoders can be unnecessarily high-dimensional. A sparse control-point parameterisation provides a compact, smooth deformation representation…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Wen Yan , Qianye Yang , Yipei Wang , Shonit Punwani , Mark Emberton , Vasilis Stavrinides , Yipeng Hu , Dean Barratt

Registration is a fundamental task in medical image analysis which can be applied to several tasks including image segmentation, intra-operative tracking, multi-modal image alignment, and motion analysis. Popular registration tools such as…

Computer Vision and Pattern Recognition · Computer Science 2019-10-07 Wentao Zhu , Andriy Myronenko , Ziyue Xu , Wenqi Li , Holger Roth , Yufang Huang , Fausto Milletari , Daguang Xu

We present a diffeomorphic image registration algorithm to learn spatial transformations between pairs of images to be registered using fully convolutional networks (FCNs) under a self-supervised learning setting. The network is trained to…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Hongming Li , Yong Fan

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Ameneh Sheikhjafari , Michelle Noga , Kumaradevan Punithakumar , Nilanjan Ray

We present a postprocessing layer for deformable image registration to make a registration field more diffeomorphic by encouraging Jacobians of the transformation to be positive. Diffeomorphic image registration is important for medical…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Soumyadeep Pal , Matthew Tennant , Nilanjan Ray

We propose FlowReg, a deep learning-based framework for unsupervised image registration for neuroimaging applications. The system is composed of two architectures that are trained sequentially: FlowReg-A which affinely corrects for gross…

Computer Vision and Pattern Recognition · Computer Science 2021-09-02 Sergiu Mocanu , Alan R. Moody , April Khademi

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Data-driven deep learning approaches to image registration can be less accurate than conventional iterative approaches, especially when training data is limited. To address this whilst retaining the fast inference speed of deep learning, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Xi Jia , Alexander Thorley , Wei Chen , Huaqi Qiu , Linlin Shen , Iain B Styles , Hyung Jin Chang , Ales Leonardis , Antonio de Marvao , Declan P. O'Regan , Daniel Rueckert , Jinming Duan

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Accurate registration of medical images is vital for doctor's diagnosis and quantitative analysis. In this paper, we propose a new deformable medical image registration method based on average geometric transformations and VoxelMorph CNN…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Yongpei Zhu , Zicong Zhou , Guojun Liao , Kehong Yuan

Diffeomorphic image registration is crucial for various medical imaging applications because it can preserve the topology of the transformation. This study introduces DCCNN-LSTM-Reg, a learning framework that evolves dynamically and learns…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Jinqiu Deng , Ke Chen , Mingke Li , Daoping Zhang , Chong Chen , Alejandro F. Frangi , Jianping Zhang

Deep neural networks are increasingly used for pair-wise image registration. We propose to extend current learning-based image registration to allow simultaneous registration of multiple images. To achieve this, we build upon the pair-wise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Tycho F. A. van der Ouderaa , Ivana Išgum , Wouter B. Veldhuis , Bob D. de Vos

Image registration is the process of bringing different images into a common coordinate system - a technique widely used in various applications of computer vision, such as remote sensing, image retrieval, and, most commonly, medical…

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