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Structured pruning is an effective approach for compressing large pre-trained neural networks without significantly affecting their performance. However, most current structured pruning methods do not provide any performance guarantees, and…

Machine Learning · Computer Science 2023-02-14 Marwa El Halabi , Suraj Srinivas , Simon Lacoste-Julien

Recently, integrating the local modeling capabilities of Convolutional Neural Networks (CNNs) with the global dependency strengths of Transformers has created a sensation in the semantic segmentation community. However, substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yangyang Qiu , Guoan Xu , Guangwei Gao , Zhenhua Guo , Yi Yu , Chia-Wen Lin

The integration of deep learning based systems in clinical practice is often impeded by challenges rooted in limited and heterogeneous medical datasets. In addition, the field has increasingly prioritized marginal performance gains on a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Sebastian Doerrich , Francesco Di Salvo , Julius Brockmann , Christian Ledig

Recent advances in de novo protein binder design have enabled increasing experimental validation, yet reported in silico metrics remain difficult to interpret or compare across studies due to non-standardized evaluation protocols. We…

Quantitative Methods · Quantitative Biology 2026-05-25 Cong Liu , Milong Ren , Jiaqi Guan , Chengyue Gong , Jinyuan Sun , Xinshi Chen , Wenzhi Xiao

Proteins and other macromolecules exist not in a single state but as dynamic ensembles of interconverting conformations, which are essential for catalysis, allosteric regulation, and molecular recognition. While AI-based structure…

Biomolecules · Quantitative Biology 2025-10-22 Stephanie A. Wankowicz , Massimiliano Bonomi

Diffusion models have shown strong capabilities in generating high-quality images from text prompts. However, these models often require large-scale training data and significant computational resources to train, or suffer from heavy…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Tong Shen , Jingai Yu , Dong Zhou , Dong Li , Emad Barsoum

Road segmentation is a fundamental perception task for autonomous driving and intelligent robotic systems, requiring both high accuracy and real-time inference, especially for deployment on resource-constrained edge devices. Existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Daojie Peng , Bingtao Wang , Fulong Ma , Liang Zhang , Jun Ma

The rapid growth of resource-constrained mobile platforms, including mobile robots, wearable systems, and Internet-of-Things devices, has increased the demand for computationally efficient neural network controllers (NNCs) that can operate…

Robotics · Computer Science 2025-08-12 Ganesh Sundaram , Jonas Ulmen , Amjad Haider , Daniel Görges

The multinomial probit model is a popular tool for analyzing choice behaviour as it allows for correlation between choice alternatives. Because current model specifications employ a full covariance matrix of the latent utilities for the…

Econometrics · Economics 2021-03-25 Ruben Loaiza-Maya , Didier Nibbering

For autoregressive modeling of chaotic dynamical systems over long time horizons, the stability of both training and inference is a major challenge in building scientific foundation models. We present a hybrid technique in which an…

Various imaging modalities are used in patient diagnosis, each offering unique advantages and valuable insights into anatomy and pathology. Computed Tomography (CT) is crucial in diagnostics, providing high-resolution images for precise…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Rabeya Tus Sadia , Jie Zhang , Jin Chen

Building a small-sized fast surveillance system model to fit on limited resource devices is a challenging, yet an important task. Convolutional Neural Networks (CNNs) have replaced traditional feature extraction and machine learning models…

Computer Vision and Pattern Recognition · Computer Science 2021-11-23 Ali Farouk Khalifa , Hesham N. Elmahdy , Eman Badr

Recent advances in Protein Structure Prediction Models (PPMs), such as AlphaFold2 and ESMFold, have revolutionized computational biology by achieving unprecedented accuracy in predicting three-dimensional protein folding structures.…

Hardware Architecture · Computer Science 2025-05-13 Seunghee Han , Soongyu Choi , Joo-Young Kim

In the ever-evolving era of Artificial Intelligence (AI), model performance has constituted a key metric driving innovation, leading to an exponential growth in model size and complexity. However, sustainability and energy efficiency have…

How can we design protein sequences folding into the desired structures effectively and efficiently? AI methods for structure-based protein design have attracted increasing attention in recent years; however, few methods can simultaneously…

Artificial Intelligence · Computer Science 2023-04-14 Zhangyang Gao , Cheng Tan , Pablo Chacón , Stan Z. Li

We propose a lightweight CPU network based on the MKLDNN acceleration strategy, named PP-LCNet, which improves the performance of lightweight models on multiple tasks. This paper lists technologies which can improve network accuracy while…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Cheng Cui , Tingquan Gao , Shengyu Wei , Yuning Du , Ruoyu Guo , Shuilong Dong , Bin Lu , Ying Zhou , Xueying Lv , Qiwen Liu , Xiaoguang Hu , Dianhai Yu , Yanjun Ma

With the surging popularity of edge computing, the need to efficiently perform neural network inference on battery-constrained IoT devices has greatly increased. While algorithmic developments enable neural networks to solve increasingly…

Hardware Architecture · Computer Science 2022-06-27 Maarten Molendijk , Floran de Putter , Henk Corporaal

Advanced automated AI techniques allow us to classify protein sequences and discern their biological families and functions. Conventional approaches for classifying these protein families often focus on extracting N-Gram features from the…

Quantitative Methods · Quantitative Biology 2024-10-24 Bahar Ali , Anwar Shah , Malik Niaz , Musadaq Mansoord , Sami Ullah , Muhammad Adnan

Diffusion models offer a powerful means of capturing the manifold of realistic protein structures, enabling rapid design for protein engineering tasks. However, existing approaches observe critical failure modes when precise constraints are…

Biomolecules · Quantitative Biology 2026-03-27 Jacob K. Christopher , Austin Seamann , Jingyi Cui , Sagar Khare , Ferdinando Fioretto

The fine-tuning paradigm has emerged as a prominent approach for addressing long-tail learning tasks in the era of foundation models. However, the impact of fine-tuning strategies on long-tail learning performance remains unexplored. In…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Jiang-Xin Shi , Tong Wei , Yu-Feng Li