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This study introduces an innovative design for a Variable Stiffness 3 Degrees of Freedom actuated wrist capable of actively and continuously adjusting its overall stiffness by modulating the active length of non-linear elastic elements.…

Robotics · Computer Science 2024-12-06 Giuseppe Milazzo , Manuel Giuseppe Catalano , Antonio Bicchi , Giorgio Grioli

High-fidelity biomechanical models usually involve the mechanical characterization of biological tissues using experimental methods based on optical measurements. In most experiments, strains are evaluated based on displacements of a few…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Ondřej Lisický , Stéphane Avril , Bastien Eydan , Baptiste Pierrat , Jiří Burša

Magnetic Resonance Imaging (MRI) is highly susceptible to motion artifacts due to the extended acquisition times required for k-space sampling. These artifacts can compromise diagnostic utility, particularly for dynamic imaging. We propose…

Image and Video Processing · Electrical Eng. & Systems 2025-07-04 Frederic Wang , Jonathan I. Tamir

Optical coherence elastography allows the characterization of the mechanical properties of tissues, and can be performed through estimating local displacement maps from subsequent acquisitions of a sample under different loads. This…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi

Palpation of human tissue during Minimally Invasive Surgery is hampered due to restricted access. In this extended abstract, we present a variable stiffness and dynamic force range sensor that has the potential to address this challenge.…

Medical Physics · Physics 2024-12-16 Abu Bakar Dawood , Zhenyu Zhang , Martin Angelmahr , Alberto Arezzo , Kaspar Althoefer

Solid stress is increasingly being recognized as a key driver of tumor progression and aggressiveness, yet it has not been directly measured in patients so far. Here, we combine multifrequency magnetic resonance elastography with 3D…

Elastographic imaging is a widely used technique which can in principle be implemented on top of every imaging modality. In elastography, the specimen is exposed to a force causing local displacements in the probe, and imaging is performed…

Optimization and Control · Mathematics 2014-07-28 Thomas Glatz , Otmar Scherzer , Thomas Widlak

Background: Mammography is a specific type of breast imaging that uses low-dose X-rays to detect cancer in early stage. During the exam, the women breast is compressed between two plates in order to even out the breast thickness and to…

Medical Physics · Physics 2018-11-27 Anna Mîra , Ann-Katherine Carton , Serge Muller , Yohan Payan

Magneto-rheological elastomers (MREs) are functional materials that can be actuated by applying an external magnetic field. MREs comprise a composite of hard magnetic particles dispersed into a nonmagnetic elastomeric matrix. By applying a…

Soft Condensed Matter · Physics 2021-12-24 Tomohiko G. Sano , Matteo Pezzulla , Pedro M. Reis

Shear wave elastography (SWE) is a promising imaging modality for mechanical characterization of tissues, offering biomarkers with potential for early and precise diagnosis. While various methods have been developed to extract mechanical…

Soft Condensed Matter · Physics 2025-07-01 Yuxuan Jiang , Guo-Yang Li , Zhaoyi Zhang , Shiyu Ma , Yanping Cao , Seok-Hyun Yun

The simulation of a short fibre reinforced structure by means of the FEM requires the knowledge of the material behaviour at every Gauss point. In order to obtain such information, a representative volume element (RVE) containing…

Materials Science · Physics 2014-08-21 N. Goldberg , H. Donner , J. Ihlemann

The measurement of cellular traction forces on soft elastic substrates has become a standard tool for many labs working on mechanobiology. Here we review the basic principles and different variants of this approach. In general, the…

Quantitative Methods · Quantitative Biology 2015-06-09 Ulrich S. Schwarz , Jerome R. D. Soine

Objectives: MR elastography (MRE) offers valuable mechanical tissue characterization, however, in deep abdominal organs like the pancreas conventional single-driver, single-frequency approaches often fail. This study evaluates whether…

The paper presents an approach for the identification of elasto-static parameters of a robotic manipulator using the virtual experiments in a CAD environment. It is based on the numerical processing of the data extracted from the finite…

Robotics · Computer Science 2013-11-27 Alexandr Klimchik , Anatol Pashkevich , Damien Chablat

We have developed a novel scanning probe-based methodology to study cell biomechanics. The time dependence of the force exerted by the cell surface on a scanning probe at constant local deformation has been used to extract local…

Biological Physics · Physics 2009-04-20 Susana Moreno-Flores , Rafael Benitez , Maria dM Vivanco , Jose Luis Toca-Herrera

The aim of this paper is to establish a nonlinear variational approach to the reconstruction of moving density images from indirect dynamic measurements. Our approach is to model the dynamics as a hyperelastic deformation of an initial…

Numerical Analysis · Mathematics 2015-12-01 Martin Burger , Jan Modersitzki , Sebastian Suhr

Ultrasound elasticity images which enable the visualization of quantitative maps of tissue stiffness can be reconstructed by solving an inverse problem. Classical model-based approaches for ultrasound elastography use deterministic finite…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Narges Mohammadi , Marvin M. Doyley , Mujdat Cetin

We derive closed-form solutions for reverberant elastography in anisotropic elastic media by adapting the framework used in electromagnetic theory to treat transverse isotropic materials. Different sample-setup geometries are analyzed,…

Medical Physics · Physics 2020-11-12 Luis A. Aleman-Castaneda , Fernando Zvietcovich , Kevin J. Parker

Shear-wave elastography (SWE) measures shear-wave speed (SWS), which is related to the underlying shear modulus of soft tissue. SWE methods generally assume that soft tissue viscoelasticity is independent of mechanical loading, however,…

Medical Physics · Physics 2022-04-21 Bhaskara R. Chintada , Richard Rau , Orcun Goksel

Tissue viscoelasticity is becoming an increasingly useful biomarker beyond elasticity and can theoretically be estimated using shear wave elastography (SWE), by inverting the propagation and attenuation characteristics of shear waves.…

Biological Physics · Physics 2024-11-19 Shuvrodeb Adikary , Matthew W. Urban , Murthy N. Guddati