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We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

Numerical Analysis · Mathematics 2022-08-12 Michele Bucelli , Alberto Zingaro , Pasquale Claudio Africa , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Empirical Dynamic Modeling (EDM) is a nonlinear time series causal inference framework. The latest implementation of EDM, cppEDM, has only been used for small datasets due to computational cost. With the growth of data collection…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-24 Wassapon Watanakeesuntorn , Keichi Takahashi , Kohei Ichikawa , Joseph Park , George Sugihara , Ryousei Takano , Jason Haga , Gerald M. Pao

Electrocardiogram (ECG) is a widely used diagnostic tool for detecting heart conditions. Rare cardiac diseases may be underdiagnosed using traditional ECG analysis, considering that no training dataset can exhaust all possible cardiac…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Aofan Jiang , Chaoqin Huang , Qing Cao , Shuang Wu , Zi Zeng , Kang Chen , Ya Zhang , Yanfeng Wang

We study the existence of weak solutions for a model of cell invasion into the extracellular matrix (ECM), which consists of a non-linear partial differential equation for the density of cells, coupled with an ordinary differential equation…

Analysis of PDEs · Mathematics 2025-01-20 Rebecca M. Crossley , Jan-Frederik Pietschmann , Markus Schmidtchen

Foundation models have recently gained significant attention because of their generalizability and adaptability across multiple tasks and data distributions. Although medical foundation models have emerged, solutions for cardiac imaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Sekeun Kim , Pengfei Jin , Sifan Song , Cheng Chen , Yiwei Li , Hui Ren , Xiang Li , Tianming Liu , Quanzheng Li

Cardiovascular disease is a large worldwide healthcare issue; symptoms often present suddenly with minimal warning. The electrocardiogram (ECG) is a fast, simple and reliable method of evaluating the health of the heart, by measuring…

Signal Processing · Electrical Eng. & Systems 2022-01-15 Yola Jones , Fani Deligianni , Jeff Dalton

Electrocardiogram (ECG) analysis plays a vital role in the early detection, monitoring, and management of various cardiovascular conditions. While existing models have achieved notable success in ECG interpretation, they fail to leverage…

Machine Learning · Computer Science 2026-03-05 Yuhao Xu , Xiaoda Wang , Jiaying Lu , Sirui Ding , Defu Cao , Huaxiu Yao , Yan Liu , Xiao Hu , Carl Yang

Neuronal and glial cells release diverse proteoglycans and glycoproteins, which aggregate in the extracellular space and form the extracellular matrix (ECM) that may in turn regulate major cellular functions. Brain cells also release…

Neurons and Cognition · Quantitative Biology 2018-07-18 Ivan Lazarevich , Sergey Stasenko , Maia Rozhnova , Evgeniya Pankratova , Alexander Dityatev , Victor Kazantsev

Model merging aims to integrate multiple task-specific fine-tuned models derived from a shared pre-trained checkpoint into a single multi-task model without additional training. Despite extensive research, task interference remains a major…

Machine Learning · Computer Science 2026-02-25 Longhua Li , Lei Qi , Qi Tian , Xin Geng

The high prevalence of cardiovascular diseases (CVDs) calls for accessible and cost-effective continuous cardiac monitoring tools. Despite Electrocardiography (ECG) being the gold standard, continuous monitoring remains a challenge, leading…

Signal Processing · Electrical Eng. & Systems 2023-12-29 Debaditya Shome , Pritam Sarkar , Ali Etemad

Emerging machine learning (ML) models (e.g., transformers) involve memory pin bandwidth-bound matrix-vector (MV) computation in inference. By avoiding pin crossings, processing in memory (PIM) can improve performance and energy for…

Hardware Architecture · Computer Science 2024-04-09 Mingxuan He , Mithuna Thottethodi , T. N. Vijaykumar

We present in this work the implementation of the Energy Conserving Semi-Implicit Method in a parallel code called ECsim. This new code is a three-dimensional, fully electromagnetic particle in cell (PIC) code. It is written in C/C++ and…

Computational Physics · Physics 2018-07-04 Diego Gonzalez-Herrero , Elisabetta Boella , Giovanni Lapenta

Heart disease remains a significant threat to human health. As a non-invasive diagnostic tool, the electrocardiogram (ECG) is one of the most widely used methods for cardiac screening. However, the scarcity of high-quality ECG data, driven…

Machine Learning · Computer Science 2025-07-22 Yongfan Lai , Jiabo Chen , Deyun Zhang , Yue Wang , Shijia Geng , Hongyan Li , Shenda Hong

Medical image segmentation is essential for clinical diagnosis, surgical planning, and treatment monitoring. Traditional approaches typically strive to tackle all medical image segmentation scenarios via one-time learning. However, in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Zhaori Liu , Mengyang Li , Hu Han , Enli Zhang , Shiguang Shan , Zhiming Zhao

ECGSYN, a dynamical model that faithfully reproduces the main features of the human electrocardiogram (ECG), including heart rate variability, RR intervals and QT intervals is presented. Details of the underlying algorithm and an…

Medical Physics · Physics 2007-05-23 Patrick E. McSharry , Gari D. Cifford

MiMiC is a framework for performing multiscale simulations in which loosely coupled external programs describe individual subsystems at different resolutions and levels of theory. To make it highly efficient and flexible, we adopt an…

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

Neural and Evolutionary Computing · Computer Science 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

As the leading candidate of quantum error correction codes, surface code suffers from significant overhead, such as execution time. Reducing the circuit's execution time not only enhances its execution efficiency but also improves fidelity.…

Quantum Physics · Physics 2023-12-27 Mingzheng Zhu , Hao Fu , Jun Wu , Chi Zhang , Wei Xie , Xiang-Yang Li

Image-based computer simulation of cardiac function can be used to probe the mechanisms of (patho)physiology, and guide diagnosis and personalized treatment of cardiac diseases. This paradigm requires constructing simulation-ready meshes of…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Fanwei Kong , Shawn C. Shadden