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Evaluating the alignment capabilities of large Vision-Language Models (VLMs) is essential for determining their effectiveness as helpful assistants. However, existing benchmarks primarily focus on basic abilities using nonverbal methods,…

Computation and Language · Computer Science 2025-06-05 Yuhang Wu , Wenmeng Yu , Yean Cheng , Yan Wang , Xiaohan Zhang , Jiazheng Xu , Ming Ding , Yuxiao Dong

Vision-language models (VLMs) are increasingly important in medical applications; however, their evaluation in dermatology remains limited by datasets that focus primarily on image-level classification tasks such as lesion recognition.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Abdurrahim Yilmaz , Ozan Erdem , Ece Gokyayla , Ayda Acar , Burc Bugra Dagtas , Dilara Ilhan Erdil , Gulsum Gencoglan , Burak Temelkuran

As Vision-Language Models (VLMs) increasingly gain traction in medical applications, clinicians are progressively expecting AI systems not only to generate textual diagnoses but also to produce corresponding medical images that integrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Junjie Yang , Yuhao Yan , Gang Wu , Yuxuan Wang , Ruoyu Liang , Xinjie Jiang , Xiang Wan , Fenglei Fan , Yongquan Zhang , Feiwei Qin , Changmiao Wang

Recent advances in large language models (LLMs) and medical LLMs (Med-LLMs) have demonstrated strong performance on general medical benchmarks. However, their capabilities in specialized medical fields, such as dentistry which require…

Computation and Language · Computer Science 2025-08-29 Hengchuan Zhu , Yihuan Xu , Yichen Li , Zijie Meng , Zuozhu Liu

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Large Vision-Language Models (LVLMs) have achieved remarkable performance in many vision-language tasks, yet their capabilities in fine-grained visual understanding remain insufficiently evaluated. Existing benchmarks either contain limited…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Fengbin Zhu , Ziyang Liu , Xiang Yao Ng , Haohui Wu , Wenjie Wang , Fuli Feng , Chao Wang , Huanbo Luan , Tat Seng Chua

Medical question answering (QA) benchmarks often focus on multiple-choice or fact-based tasks, leaving open-ended answers to real patient questions underexplored. This gap is particularly critical in mental health, where patient questions…

Computation and Language · Computer Science 2026-05-15 Yahan Li , Jifan Yao , John Bosco S. Bunyi , Adam C. Frank , Angel Hsing-Chi Hwang , Ruishan Liu

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Spectra are a prevalent yet highly information-dense form of scientific imagery, presenting substantial challenges to multimodal large language models (MLLMs) due to their unstructured and domain-specific characteristics. Here we introduce…

Artificial Intelligence · Computer Science 2026-05-01 Jialu Shen , Han Lyu , Suyang Zhong , Hanzheng Li , Haoyi Tao , Nan Wang , Changhong Chen , Xi Fang

Vision-Language Models (VLMs) have demonstrated remarkable capabilities in general video understanding, yet they often struggle with the fine-grained comprehension crucial for real-world applications requiring nuanced interpretation of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Gueter Josmy Faure , Min-Hung Chen , Jia-Fong Yeh , Hung-Ting Su , Winston H. Hsu

Multimodal Large Language Models (MLLMs) have shown remarkable proficiency on general-purpose vision-language benchmarks, reaching or even exceeding human-level performance. However, these evaluations typically rely on standard…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Wenjin Hou , Wei Liu , Han Hu , Xiaoxiao Sun , Serena Yeung-Levy , Hehe Fan

Multimodal large language models (MLLMs) hold significant potential in medical applications, including disease diagnosis and clinical decision-making. However, these tasks require highly accurate, context-sensitive, and professionally…

Computation and Language · Computer Science 2025-09-01 Meidan Ding , Jipeng Zhang , Wenxuan Wang , Cheng-Yi Li , Wei-Chieh Fang , Hsin-Yu Wu , Haiqin Zhong , Wenting Chen , Linlin Shen

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to…

Advancements in Multimodal Large Language Models (MLLMs) have significantly improved medical task performance, such as Visual Question Answering (VQA) and Report Generation (RG). However, the fairness of these models across diverse…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Peiran Wu , Che Liu , Canyu Chen , Jun Li , Cosmin I. Bercea , Rossella Arcucci

With the rapid development of Multi-modal Large Language Models (MLLMs), a number of diagnostic benchmarks have recently emerged to evaluate the comprehension capabilities of these models. However, most benchmarks predominantly assess…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Kunchang Li , Yali Wang , Yinan He , Yizhuo Li , Yi Wang , Yi Liu , Zun Wang , Jilan Xu , Guo Chen , Ping Luo , Limin Wang , Yu Qiao

Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Alejandro Lozano , Jeffrey Nirschl , James Burgess , Sanket Rajan Gupte , Yuhui Zhang , Alyssa Unell , Serena Yeung-Levy

The robust safety of Vision-Language Large Models (VLLMs) against joint multilingual and multimodal threats remains severely underexplored. Current benchmarks typically isolate these dimensions, being either multilingual but text-only, or…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Enyi Shi , Pengyang Shao , Yanxin Zhang , Chenhang Cui , Jiayi Lyu , Xiaobo Xia , Fei Shen , Tat-Seng Chua

Multimodal/vision language models (VLMs) are increasingly being deployed in healthcare settings worldwide, necessitating robust benchmarks to ensure their safety, efficacy, and fairness. Multiple-choice question and answer (QA) datasets…

Large Multimodal Models (LMMs) exhibit major shortfalls when interpreting images and, by some measures, have poorer spatial cognition than small children or animals. Despite this, they attain high scores on many popular visual benchmarks,…