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In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

Medical question answering (QA) benchmarks often focus on multiple-choice or fact-based tasks, leaving open-ended answers to real patient questions underexplored. This gap is particularly critical in mental health, where patient questions…

Computation and Language · Computer Science 2026-05-15 Yahan Li , Jifan Yao , John Bosco S. Bunyi , Adam C. Frank , Angel Hsing-Chi Hwang , Ruishan Liu

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Information Retrieval · Computer Science 2026-04-14 Avi-ad Avraam Buskila

As large language models (LLMs) are adopted in an increasingly wide range of applications, user-model interactions have grown in both frequency and scale. Consequently, research has focused on evaluating the robustness of LLMs, an essential…

Computation and Language · Computer Science 2025-11-17 Jiahang He , Rishi Ramachandran , Neel Ramachandran , Aryan Katakam , Kevin Zhu , Sunishchal Dev , Ashwinee Panda , Aryan Shrivastava

Medical reasoning models (MRMs) achieve superior performance on medical benchmarks compared to medical LLMs; however, high accuracy alone is insufficient for practical deployment. One of such requirements for real-world application is…

Medical question-answering benchmarks predominantly evaluate single-turn exchanges, failing to capture the iterative, clarification-seeking nature of real patient consultations. We introduce ThReadMed-QA, a benchmark of 2,437 fully-answered…

Computation and Language · Computer Science 2026-03-13 Monica Munnangi , Saiph Savage

The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific…

Computation and Language · Computer Science 2025-03-11 Luyi Jiang , Jiayuan Chen , Lu Lu , Xinwei Peng , Lihao Liu , Junjun He , Jie Xu

With the increasing use of large language models (LLMs) in medical decision-support, it is essential to evaluate not only their final answers but also the reliability of their reasoning. Two key risks are Chain-of-Thought (CoT) faithfulness…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Kaiyuan Ji , Yijin Guo , Zicheng Zhang , Xiangyang Zhu , Yuan Tian , Ning Liu , Guangtao Zhai

Language models, characterized by their black-box nature, often hallucinate and display sensitivity to input perturbations, causing concerns about trust. To enhance trust, it is imperative to gain a comprehensive understanding of the…

Computation and Language · Computer Science 2025-01-03 Vatsal Gupta , Pranshu Pandya , Tushar Kataria , Vivek Gupta , Dan Roth

Multi-Turn Long-Form Question Answering (MT-LFQA) is a key application paradigm of Large Language Models (LLMs) in knowledge-intensive domains. However, existing benchmarks are limited to single-turn dialogue, while multi-turn dialogue…

Computation and Language · Computer Science 2025-09-29 Junhao Chen , Yu Huang , Siyuan Li , Rui Yao , Hanqian Li , Hanyu Zhang , Jungang Li , Jian Chen , Bowen Wang , Xuming Hu

Large Language Models (LLMs) are expected to provide helpful and harmless responses, yet they often exhibit sycophancy--conforming to user beliefs regardless of factual accuracy or ethical soundness. Prior research on sycophancy has…

Computation and Language · Computer Science 2026-03-02 Jiseung Hong , Grace Byun , Seungone Kim , Kai Shu , Jinho D. Choi

Large Language Models (LLMs), characterized by being trained on broad amounts of data in a self-supervised manner, have shown impressive performance across a wide range of tasks. Indeed, their generative abilities have aroused interest on…

Machine Learning · Computer Science 2024-07-30 Jorge García-Carrasco , Alejandro Maté , Juan Trujillo

Large Language Models (LLMs) are prone to generating fluent but incorrect content, known as confabulation, which poses increasing risks in multi-turn or agentic applications where outputs may be reused as context. In this work, we…

Computation and Language · Computer Science 2026-03-18 Tianyi Zhou , Johanne Medina , Sanjay Chawla

Large Language Models are a promising tool for automated vulnerability detection, thanks to their success in code generation and repair. However, despite widespread adoption, a critical question remains: Are LLMs truly effective at…

Cryptography and Security · Computer Science 2025-04-21 Yue Li , Xiao Li , Hao Wu , Minghui Xu , Yue Zhang , Xiuzhen Cheng , Fengyuan Xu , Sheng Zhong

Large Language Models (LLMs), already shown to ace various unstructured text comprehension tasks, have also remarkably been shown to tackle table (structured) comprehension tasks without specific training. Building on earlier studies of…

Computation and Language · Computer Science 2025-08-27 Kushal Raj Bhandari , Sixue Xing , Soham Dan , Jianxi Gao

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

Large Language Models (LLMs) should answer factual questions truthfully, grounded in objective knowledge, regardless of user context such as self-disclosed personal information, or system personalization. In this paper, we present the first…

Computation and Language · Computer Science 2025-10-16 Nil-Jana Akpinar , Chia-Jung Lee , Vanessa Murdock , Pietro Perona

Language Models (LMs) are being proposed for mental health applications where the heightened risk of adverse outcomes means predictive performance may not be a sufficient litmus test of a model's utility in clinical practice. A model that…

Artificial Intelligence · Computer Science 2024-12-05 Seyedali Mohammadi , Edward Raff , Jinendra Malekar , Vedant Palit , Francis Ferraro , Manas Gaur

Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may…

Machine Learning · Computer Science 2025-11-21 Dong Chen , Yanzhe Wei , Zonglin He , Guan-Ming Kuang , Canhua Ye , Meiru An , Huili Peng , Yong Hu , Huiren Tao , Kenneth MC Cheung

The application of large language models (LLMs) in healthcare holds significant promise for enhancing clinical decision-making, medical research, and patient care. However, their integration into real-world clinical settings raises critical…

Computers and Society · Computer Science 2025-09-18 Manar Aljohani , Jun Hou , Sindhura Kommu , Xuan Wang