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Clinical diagnosis is time-consuming, requiring intensive interactions between patients and medical professionals. While large language models (LLMs) could ease the pre-diagnostic workload, their limited domain knowledge hinders effective…

Computation and Language · Computer Science 2026-03-03 Liwen Sun , Xiang Yu , Ming Tan , Zhuohao Chen , Anqi Cheng , Ashutosh Joshi , Chenyan Xiong

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

The advent of Large Language Models (LLMs) has significantly transformed the AI landscape, enhancing machine learning and AI capabilities. Factuality issue is a critical concern for LLMs, as they may generate factually incorrect responses.…

Computation and Language · Computer Science 2024-04-02 Xiaoze Liu , Feijie Wu , Tianyang Xu , Zhuo Chen , Yichi Zhang , Xiaoqian Wang , Jing Gao

With appropriate data selection and training techniques, Large Language Models (LLMs) have demonstrated exceptional success in various medical examinations and multiple-choice questions. However, the application of LLMs in medical dialogue…

Computation and Language · Computer Science 2024-03-12 Jiageng Wu , Xian Wu , Yefeng Zheng , Jie Yang

Large Language Models (LLMs) possess human-level cognitive and decision-making capabilities, making them a key technology for 6G. However, applying LLMs to the communication domain faces three major challenges: 1) Inadequate communication…

Information Theory · Computer Science 2025-02-27 Feibo Jiang , Wanyun Zhu , Li Dong , Kezhi Wang , Kun Yang , Cunhua Pan , Octavia A. Dobre

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose…

Computation and Language · Computer Science 2025-02-18 Alexandru Lecu , Adrian Groza , Lezan Hawizy

Clinical guidelines, typically structured as decision trees, are central to evidence-based medical practice and critical for ensuring safe and accurate diagnostic decision-making. However, it remains unclear whether Large Language Models…

Computation and Language · Computer Science 2025-05-20 Xiaomin Li , Mingye Gao , Yuexing Hao , Taoran Li , Guangya Wan , Zihan Wang , Yijun Wang

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Large Language Models (LLMs) are increasingly employed in multi-turn conversational tasks, yet their pre-training data predominantly consists of continuous prose, creating a potential mismatch between required capabilities and training…

Computation and Language · Computer Science 2025-07-09 Jing Yang Lee , Hamed Bonab , Nasser Zalmout , Ming Zeng , Sanket Lokegaonkar , Colin Lockard , Binxuan Huang , Ritesh Sarkhel , Haodong Wang

With the proliferation of large language models (LLMs) in the medical domain, there is increasing demand for improved evaluation techniques to assess their capabilities. However, traditional metrics like F1 and ROUGE, which rely on token…

Computation and Language · Computer Science 2025-05-20 Xiechi Zhang , Zetian Ouyang , Linlin Wang , Gerard de Melo , Zhu Cao , Xiaoling Wang , Ya Zhang , Yanfeng Wang , Liang He

Mental health has attracted substantial attention in recent years and LLM can be an effective technology for alleviating this problem owing to its capability in text understanding and dialogue. However, existing research in this domain…

Computation and Language · Computer Science 2024-12-09 Jinpeng Hu , Tengteng Dong , Luo Gang , Hui Ma , Peng Zou , Xiao Sun , Dan Guo , Xun Yang , Meng Wang

Knowledge graphs are widely used in industrial applications, making error detection crucial for ensuring the reliability of downstream applications. Existing error detection methods often fail to effectively utilize fine-grained subgraph…

Artificial Intelligence · Computer Science 2025-11-20 Yu Li , Yi Huang , Guilin Qi , Junlan Feng , Nan Hu , Songlin Zhai , Haohan Xue , Yongrui Chen , Ruoyan Shen , Tongtong Wu

As multimodal LLM-driven agents advance in autonomy and generalization, traditional static datasets face inherent scalability limitations and are insufficient for fully assessing their capabilities in increasingly complex and diverse tasks.…

Computation and Language · Computer Science 2026-03-06 Yurun Chen , Xavier Hu , Yuhan Liu , Ziqi Wang , Zeyi Liao , Lin Chen , Feng Wei , Yuxi Qian , Bo Zheng , Keting Yin , Shengyu Zhang

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

Computation and Language · Computer Science 2025-01-30 Vahan Arsenyan , Spartak Bughdaryan , Fadi Shaya , Kent Small , Davit Shahnazaryan

Large language models (LLMs) struggle in real-world clinical consultations. Single-turn consultation systems require patients to describe all symptoms at once, which often leads to unclear complaints and vague diagnoses. Traditional…

Computation and Language · Computer Science 2026-05-01 Yichun Feng , Jiawei Wang , Lu Zhou , Yikai Zheng , Zhen Lei , Yixue Li

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

Computation and Language · Computer Science 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Emergency management urgently requires comprehensive knowledge while having a high possibility to go beyond individuals' cognitive scope. Therefore, artificial intelligence(AI) supported decision-making under that circumstance is of vital…

Computation and Language · Computer Science 2023-11-16 Minze Chen , Zhenxiang Tao , Weitong Tang , Tingxin Qin , Rui Yang , Chunli Zhu

Recent advances in natural language processing (NLP) owe their success to pre-training language models on large amounts of unstructured data. Still, there is an increasing effort to combine the unstructured nature of LMs with structured…

Computation and Language · Computer Science 2023-12-22 Juraj Vladika , Alexander Fichtl , Florian Matthes

The recent proliferation of large language models (LLMs) holds the potential to revolutionize healthcare, with strong capabilities in diverse medical tasks. Yet, deploying LLMs in high-stakes healthcare settings requires rigorous…

Machine Learning · Computer Science 2025-12-22 Shasha Zhou , Mingyu Huang , Jack Cole , Charles Britton , Ming Yin , Jan Wolber , Ke Li

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan
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