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Related papers: MedKGEval: A Knowledge Graph-Based Multi-Turn Eval…

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Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Evaluating multi-turn dialogue systems remains challenging because response quality depends not only on the current prompt, but also on previously established entities, claims, and conversational commitments. Existing automatic evaluators,…

Computation and Language · Computer Science 2026-05-19 Avijit Shil , Suman Samui

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

The transition towards patient-centric healthcare necessitates a comprehensive understanding of patient journeys, which encompass all healthcare experiences and interactions across the care spectrum. Existing healthcare data systems are…

Computation and Language · Computer Science 2025-03-24 Hassan S. Al Khatib , Sudip Mittal , Shahram Rahimi , Nina Marhamati , Sean Bozorgzad

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…

Computation and Language · Computer Science 2026-05-18 Weixin Liu , Congning Ni , Shelagh A. Mulvaney , Susannah L. Rose , Murat Kantarcioglu , Bradley A. Malin , Zhijun Yin

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

Computation and Language · Computer Science 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Answering complex real-world questions in the medical domain often requires accurate retrieval from medical Textual Knowledge Graphs (medical TKGs), as the relational path information from TKGs could enhance the inference ability of Large…

Computation and Language · Computer Science 2026-04-14 Jiatan Huang , Mingchen Li , Zonghai Yao , Dawei Li , Yuxin Zhang , Zhichao Yang , Yongkang Xiao , Feiyun Ouyang , Xiaohan Li , Shuo Han , Hong Yu

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

The rapid advancement of Large Language Models (LLMs) and conversational assistants necessitates dynamic, scalable, and configurable conversational datasets for training and evaluation. These datasets must accommodate diverse user…

Computation and Language · Computer Science 2024-08-13 Ronak Pradeep , Daniel Lee , Ali Mousavi , Jeff Pound , Yisi Sang , Jimmy Lin , Ihab Ilyas , Saloni Potdar , Mostafa Arefiyan , Yunyao Li

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

Computation and Language · Computer Science 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Current large language models (LLMs) excel at general NLP tasks but often lack domain specific precision in professional settings. Building a high quality domain specific multi turn dialogue dataset is essential for developing specialized…

Artificial Intelligence · Computer Science 2025-08-05 Yuanyuan Liang , Xiaoman Wang , Tingyu Xie , Lei Pan

With the growing use of language models (LMs) in clinical environments, there is an immediate need to evaluate the accuracy and safety of LM-generated medical text. Currently, such evaluation relies solely on manual physician review.…

Mastering medical knowledge is crucial for medical-specific LLMs. However, despite the existence of medical benchmarks like MedQA, a unified framework that fully leverages existing knowledge bases to evaluate LLMs' mastery of medical…

Computation and Language · Computer Science 2024-10-03 Yuxuan Zhou , Xien Liu , Chen Ning , Xiao Zhang , Ji Wu

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Automatic evaluation methods for large language models (LLMs) are hindered by data contamination, leading to inflated assessments of their effectiveness. Existing strategies, which aim to detect contaminated texts, focus on quantifying…

Computation and Language · Computer Science 2024-06-04 Zhuohao Yu , Chang Gao , Wenjin Yao , Yidong Wang , Wei Ye , Jindong Wang , Xing Xie , Yue Zhang , Shikun Zhang

The rapid expansion of medical literature presents growing challenges for structuring and integrating domain knowledge at scale. Knowledge Graphs (KGs) offer a promising solution by enabling efficient retrieval, automated reasoning, and…

Computation and Language · Computer Science 2025-08-20 Duzhen Zhang , Zixiao Wang , Zhong-Zhi Li , Yahan Yu , Shuncheng Jia , Jiahua Dong , Haotian Xu , Xing Wu , Yingying Zhang , Tielin Zhang , Jie Yang , Xiuying Chen , Le Song

Clinical practice guidelines (CPGs) play a pivotal role in ensuring evidence-based decision-making and improving patient outcomes. While Large Language Models (LLMs) are increasingly deployed in healthcare scenarios, it is unclear to which…

Computation and Language · Computer Science 2026-03-27 Andong Tan , Shuyu Dai , Jinglu Wang , Fengtao Zhou , Yan Lu , Xi Wang , Yingcong Chen , Can Yang , Shujie Liu , Hao Chen

Demand for mental health support through AI chatbots is surging, though current systems present several limitations, like sycophancy or overvalidation, and reinforcement of maladaptive beliefs. A core obstacle to the creation of better…

Computation and Language · Computer Science 2025-12-08 José Pombal , Maya D'Eon , Nuno M. Guerreiro , Pedro Henrique Martins , António Farinhas , Ricardo Rei
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