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A large number of biological systems - from bacteria to sheep - can be described as ensembles of self-propelled agents (active particles) with a complex internal dynamic that controls the agent's behavior: resting, moving slow, moving fast,…

Biological Physics · Physics 2021-09-03 L. Gómez-Nava , T. Goudon , F. Peruani

Travelling wave solutions of reaction-diffusion equations are widely used to model the spatial spread of populations and other phenomena in biology and physics. In this article, we reinterpret the classical variational principle approach…

Analysis of PDEs · Mathematics 2026-03-19 Rebecca M. Crossley , Carles Falco , Ruth E. Baker

Navigating our physical environment requires changing directions and turning. Despite its ecological importance, we do not have a unified theoretical account of non-straight-line human movement. Here, we present a unified optimality…

Neurons and Cognition · Quantitative Biology 2021-11-03 Geoffrey L. Brown , Nidhi Seethapathi , Manoj Srinivasan

Chemotaxis, i.e. motion generated by chemical gradients, is a motility mode shared by many living species that has been developed by evolution to optimize certain biological processes such as foraging or immune response. In particular,…

Soft Condensed Matter · Physics 2023-05-24 Hugues Meyer , Heiko Rieger

Limbless crawling is ubiquitous in biology, from cells to organisms. We develop and analyze a model for the dynamics of one-dimensional elastic crawlers, subject to active stress and deformation-dependent friction with the substrate. We…

Soft Condensed Matter · Physics 2022-09-14 Sreejith Santhosh , Mattia Serra

Information routing is one of the main tasks in many complex networks with a communication function. Maps produced by embedding the networks in hyperbolic space can assist this task enabling the implementation of efficient navigation…

Physics and Society · Physics 2017-09-11 Elisenda Ortiz , Michele Starnini , M. Ángeles Serrano

Collective migration of eukaryotic cells is often guided by chemotaxis, and is critical in several biological processes, such as cancer metastasis, wound healing, and embryogenesis. Understanding collective chemotaxis has challenged…

Biological Physics · Physics 2024-08-12 Aditya Paspunurwar , Adrian Moure , Hector Gomez

A stochastic walker model is proposed to describe the chemotactic guidance of growth cones, i.e. the tips of developing neurites. The model accounts for the influence of both attractive and repulsive chemical cues, which are emitted by the…

Analysis of PDEs · Mathematics 2025-11-04 Noah Geltner , Ansgar Jüngel

Understanding how decision makers balance operational efficiency with environmental and ecological risks is central to vessel navigation. We model vessel speed as a control variable in a constrained optimization framework in which vessel…

Applications · Statistics 2026-05-27 Mauli Pant , Linda Fernandez , Indranil Sahoo

Continuum models of active nematic gels have proved successful to describe a number of biological systems consisting of a population of rodlike motile subunits in a fluid environment. However, in order to get a thorough understanding of the…

Soft Condensed Matter · Physics 2023-05-03 Stefano Turzi

Robust evidence suggests that humans explore their environment using a combination of topological landmarks and coarse-grained path integration. This approach relies on identifiable environmental features (topological landmarks) in tandem…

Robotics · Computer Science 2024-09-16 Daria de Tinguy , Toon van de Maele , Tim Verbelen , Bart Dhoedt

This work presents a density-based framework for safe navigation in dynamic environments characterized by time-varying obstacle sets and time-varying target regions. We propose an analytical construction of time-varying density functions…

Robotics · Computer Science 2025-06-10 Sriram S. K. S Narayanan , Joseph Moyalan , Umesh Vaidya

Collective migration -- the directed, coordinated motion of many self-propelled agents -- is a fascinating emergent behavior exhibited by active matter that has key functional implications for biological systems. Extensive studies have…

Biological Physics · Physics 2022-06-07 Tapomoy Bhattacharjee , Daniel B. Amchin , Ricard Alert , J. A. Ott , Sujit S. Datta

Microorganisms often encounter strong confinement and complex hydrodynamic flows while navigating their habitats. Combining finite-element methods and stochastic simulations, we study the interplay of active transport and heterogeneous…

Soft Condensed Matter · Physics 2025-11-05 Pallabi Das , Mirko Residori , Axel Voigt , Suvendu Mandal , Christina Kurzthaler

Motivated by a recent prediction to engineer the dispersion relation of a waveguide constructed from atomic components [arXiv:2104.08121], we explore the possibility to create directional transport in an open, collective quantum system. The…

Quantum Physics · Physics 2022-04-05 R. Gutiérrez-Jáuregui , A. Asenjo-Garcia

Bacteria can chemotactically migrate up attractant gradients by controlling run-and-tumble motility patterns. In addition to this well-known chemotactic behaviour, several soil and marine bacterial species perform chemokinesis: they adjust…

Biological Physics · Physics 2021-03-19 Theresa Jakuszeit , James Lindsey-Jones , François J. Peaudecerf , Ottavio A. Croze

Animals employ different strategies for relating sensory input to behavioral output to navigate sensory environments, but what strategy to use, when to switch and why remain unclear. In C. elegans, navigation is composed of 'steering' and…

Neurons and Cognition · Quantitative Biology 2025-08-04 Kevin S. Chen , Andrew M. Leifer , Jonathan W. Pillow

We propose two nonlinear random walk models which are suitable for the analysis of both chemotaxis and anomalous transport. We derive the balance equations for the population density for the case when the transition rate for a random walk…

Statistical Mechanics · Physics 2010-10-22 Sergei Fedotov

The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…

Cell Behavior · Quantitative Biology 2007-05-23 Radek Erban , Hans G. Othmer

Quantifying how spatial disorder affects the movement of a diffusing particle or agent is fundamental to target search studies. When diffusion occurs on a network, that is on a highly disordered environment, we lack the mathematical tools…

Statistical Mechanics · Physics 2025-08-15 Daniel Marris , Chittaranjan Hens , Subrata Ghosh , Luca Giuggioli